Faster onset time of supraclavicular brachial plexus block using local anesthetic diluted with dextrose
Background and objectives: A high sodium concentration is known to antagonize local anesthetics when infiltrated around neural tissue. Thus, we hypothesized that the onset time for sensory and motor blockade, in supraclavicular brachial plexus block using ropivacaine diluted with dextrose would be s...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2016-07-01
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| Series: | Brazilian Journal of Anesthesiology |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S0104001415001098 |
| _version_ | 1811236761814171648 |
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| author | Hong Jin Lim Mohd Shahnaz Hasan Karuthan Chinna |
| author_facet | Hong Jin Lim Mohd Shahnaz Hasan Karuthan Chinna |
| author_sort | Hong Jin Lim |
| collection | DOAJ |
| description | Background and objectives: A high sodium concentration is known to antagonize local anesthetics when infiltrated around neural tissue. Thus, we hypothesized that the onset time for sensory and motor blockade, in supraclavicular brachial plexus block using ropivacaine diluted with dextrose would be shorter than with saline. Methods: Patients scheduled for upper limb surgery were randomized to receive ultrasound guided supraclavicular brachial plexus block with 0.5% ropivacaine. Evaluation of sensory and motor blockade was performed every 5 min for 60 min. Patients were followed-up on postoperative day 1, and between days 7 and 10 for the presence of any complications. Twenty-five patients in each group were analyzed. Results: Mean time for onset of analgesia for the dextrose group was 37.6 ± 12.9 min while the mean time for the saline group was 45.2 ± 13.9 min with a p-value of 0.05. The effect size was 0.567, which was moderate to large. No major complications were observed. Conclusion: We conclude that there was a decrease in onset time of analgesia when dextrose was used as a diluent instead of saline for ultrasound guided supraclavicular block. Resumo: Justificativa e objetivos: A alta concentração de sódio é conhecida por antagonizar anestésicos locais quando infiltrado em torno de tecido neural. Portanto, a nossa hipótese foi a de que o tempo de início para os bloqueios sensorial e motor, em bloqueio do plexo braquial supraclavicular usando ropivacaína diluída com dextrose, seria menor do que com solução salina. Métodos: Os pacientes agendados para cirurgia em membro superior foram randomizados para receber bloqueio do plexo braquial supraclavicular com ropivacaína a 0,5%g guiado por ultrassom. A avaliação dos bloqueios sensorial e motor foi realizada a cada 5 minutos durante 60 minutos. Os pacientes foram acompanhados no pós-operatório no primeiro dia e, entre os dias 7-10 para presença de qualquer complicação. Foram analisados 25 pacientes em cada grupo. Resultados: A média do tempo para o início da analgesia no grupo dextrose foi de 37,6 ± 12,9 minutos, enquanto que no grupo solução salina a média foi de 45,2 ± 13,9 minutos, com um valor-p de 0,05. O tamanho do efeito foi 0,567, o que foi de moderado a grande. Complicações maiores não foram observadas. Conclusão: Concluimos que houve uma redução do tempo de início da analgesia quando dextrose em vez de solução salina foi usada como diluente para bloqueio supraclavicular guiado por ultrassom. Keywords: Ultrasound, Supraclavicular, Brachial plexus, Block, Saline, Dextrose, Palavras-chave: Ultrassom, Supraclavicular, Plexo braquial, Bloqueio, Solução salina, Dextrose |
| first_indexed | 2024-04-12T12:13:47Z |
| format | Article |
| id | doaj.art-9e286c0f1169478182de1ff27637daf1 |
| institution | Directory Open Access Journal |
| issn | 0104-0014 |
| language | English |
| last_indexed | 2024-04-12T12:13:47Z |
| publishDate | 2016-07-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Brazilian Journal of Anesthesiology |
| spelling | doaj.art-9e286c0f1169478182de1ff27637daf12022-12-22T03:33:30ZengElsevierBrazilian Journal of Anesthesiology0104-00142016-07-01664341345Faster onset time of supraclavicular brachial plexus block using local anesthetic diluted with dextroseHong Jin Lim0Mohd Shahnaz Hasan1Karuthan Chinna2Department of Anesthesiology, Faculty of Medicine, University of Malaya, 50603 Kuala Lumpur, MalaysiaDepartment of Anesthesiology, Faculty of Medicine, University of Malaya, 50603 Kuala Lumpur, Malaysia; Corresponding author.Julius Centre University Malaya, Department of Social and Preventive Medicine, Faculty of Medicine, University of Malaya, 50603 Kuala Lumpur, MalaysiaBackground and objectives: A high sodium concentration is known to antagonize local anesthetics when infiltrated around neural tissue. Thus, we hypothesized that the onset time for sensory and motor blockade, in supraclavicular brachial plexus block using ropivacaine diluted with dextrose would be shorter than with saline. Methods: Patients scheduled for upper limb surgery were randomized to receive ultrasound guided supraclavicular brachial plexus block with 0.5% ropivacaine. Evaluation of sensory and motor blockade was performed every 5 min for 60 min. Patients were followed-up on postoperative day 1, and between days 7 and 10 for the presence of any complications. Twenty-five patients in each group were analyzed. Results: Mean time for onset of analgesia for the dextrose group was 37.6 ± 12.9 min while the mean time for the saline group was 45.2 ± 13.9 min with a p-value of 0.05. The effect size was 0.567, which was moderate to large. No major complications were observed. Conclusion: We conclude that there was a decrease in onset time of analgesia when dextrose was used as a diluent instead of saline for ultrasound guided supraclavicular block. Resumo: Justificativa e objetivos: A alta concentração de sódio é conhecida por antagonizar anestésicos locais quando infiltrado em torno de tecido neural. Portanto, a nossa hipótese foi a de que o tempo de início para os bloqueios sensorial e motor, em bloqueio do plexo braquial supraclavicular usando ropivacaína diluída com dextrose, seria menor do que com solução salina. Métodos: Os pacientes agendados para cirurgia em membro superior foram randomizados para receber bloqueio do plexo braquial supraclavicular com ropivacaína a 0,5%g guiado por ultrassom. A avaliação dos bloqueios sensorial e motor foi realizada a cada 5 minutos durante 60 minutos. Os pacientes foram acompanhados no pós-operatório no primeiro dia e, entre os dias 7-10 para presença de qualquer complicação. Foram analisados 25 pacientes em cada grupo. Resultados: A média do tempo para o início da analgesia no grupo dextrose foi de 37,6 ± 12,9 minutos, enquanto que no grupo solução salina a média foi de 45,2 ± 13,9 minutos, com um valor-p de 0,05. O tamanho do efeito foi 0,567, o que foi de moderado a grande. Complicações maiores não foram observadas. Conclusão: Concluimos que houve uma redução do tempo de início da analgesia quando dextrose em vez de solução salina foi usada como diluente para bloqueio supraclavicular guiado por ultrassom. Keywords: Ultrasound, Supraclavicular, Brachial plexus, Block, Saline, Dextrose, Palavras-chave: Ultrassom, Supraclavicular, Plexo braquial, Bloqueio, Solução salina, Dextrosehttp://www.sciencedirect.com/science/article/pii/S0104001415001098 |
| spellingShingle | Hong Jin Lim Mohd Shahnaz Hasan Karuthan Chinna Faster onset time of supraclavicular brachial plexus block using local anesthetic diluted with dextrose Brazilian Journal of Anesthesiology |
| title | Faster onset time of supraclavicular brachial plexus block using local anesthetic diluted with dextrose |
| title_full | Faster onset time of supraclavicular brachial plexus block using local anesthetic diluted with dextrose |
| title_fullStr | Faster onset time of supraclavicular brachial plexus block using local anesthetic diluted with dextrose |
| title_full_unstemmed | Faster onset time of supraclavicular brachial plexus block using local anesthetic diluted with dextrose |
| title_short | Faster onset time of supraclavicular brachial plexus block using local anesthetic diluted with dextrose |
| title_sort | faster onset time of supraclavicular brachial plexus block using local anesthetic diluted with dextrose |
| url | http://www.sciencedirect.com/science/article/pii/S0104001415001098 |
| work_keys_str_mv | AT hongjinlim fasteronsettimeofsupraclavicularbrachialplexusblockusinglocalanestheticdilutedwithdextrose AT mohdshahnazhasan fasteronsettimeofsupraclavicularbrachialplexusblockusinglocalanestheticdilutedwithdextrose AT karuthanchinna fasteronsettimeofsupraclavicularbrachialplexusblockusinglocalanestheticdilutedwithdextrose |