Processing Oscillatory Signals by Incoherent Feedforward Loops.
From the timing of amoeba development to the maintenance of stem cell pluripotency, many biological signaling pathways exhibit the ability to differentiate between pulsatile and sustained signals in the regulation of downstream gene expression. While the networks underlying this signal decoding are...
Main Authors: | Carolyn Zhang, Ryan Tsoi, Feilun Wu, Lingchong You |
---|---|
Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2016-09-01
|
Series: | PLoS Computational Biology |
Online Access: | http://europepmc.org/articles/PMC5021367?pdf=render |
Similar Items
-
An incoherent feedforward loop facilitates adaptive tuning of gene expression
by: Jungeui Hong, et al.
Published: (2018-04-01) -
The role of incoherent microRNA-mediated feedforward loops in noise buffering.
by: Matteo Osella, et al.
Published: (2011-03-01) -
The engineering principles of combining a transcriptional incoherent feedforward loop with negative feedback
by: Gregory T. Reeves
Published: (2019-07-01) -
An incoherent feedforward loop interprets NFκB/RelA dynamics to determine TNF‐induced necroptosis decisions
by: Marie Oliver Metzig, et al.
Published: (2020-12-01) -
Synthetic incoherent feedforward circuits show adaptation to the amount of their genetic template
by: Bleris, Leonidas, et al.
Published: (2013)