Exploring the protective effect of Sangggua Drink against type 2 diabetes mellitus in db/db mice using a network pharmacological approach and experimental validation

Exploring the protective effect of Sangggua Drink against type 2 diabetes mellitus in db/db mice using a network pharmacological approach and experimental validation

Sanggua Drink (SGD) is an experienced formula for clinical treatment of type 2 diabetes mellitus (T2DM). Network pharmacology and experiments were combined to explore the potential mechanism of action of SGD on T2DM. The material basis and action mechanism of SGD were investigated to reveal the acti...

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Bibliographic Details
Main Authors: Yu Cai, Simin Liu, Fei Zeng, Zhiwei Rao, Chunchao Yan, Qichang Xing, Yunzhong Chen
Format: Article
Language:English
Published: Elsevier 2023-07-01
Series:Heliyon
Subjects:
Sanggua drink
T2DM
AMPK/Akt
db/db mice
Insulin resistance
Online Access:http://www.sciencedirect.com/science/article/pii/S2405844023052349

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http://www.sciencedirect.com/science/article/pii/S2405844023052349

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