Exploring the protective effect of Sangggua Drink against type 2 diabetes mellitus in db/db mice using a network pharmacological approach and experimental validation
Sanggua Drink (SGD) is an experienced formula for clinical treatment of type 2 diabetes mellitus (T2DM). Network pharmacology and experiments were combined to explore the potential mechanism of action of SGD on T2DM. The material basis and action mechanism of SGD were investigated to reveal the acti...
Main Authors: | Yu Cai, Simin Liu, Fei Zeng, Zhiwei Rao, Chunchao Yan, Qichang Xing, Yunzhong Chen |
---|---|
Format: | Article |
Language: | English |
Published: |
Elsevier
2023-07-01
|
Series: | Heliyon |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2405844023052349 |
Similar Items
-
Antidiabetic Effect of Tibetan Medicine Tang-Kang-Fu-San in db/db Mice via Activation of PI3K/Akt and AMPK Pathways
by: Bailu Duan, et al.
Published: (2017-08-01) -
Salidroside Affects Gut Microbiota Structure in db/db Mice by Affecting Insulin, Blood Glucose and Body Weight
by: Zhao Q, et al.
Published: (2022-08-01) -
Antidiabetic Effect of Artemether in Db/Db Mice Involves Regulation of AMPK and PI3K/Akt Pathways
by: Xiaolin Bai, et al.
Published: (2020-09-01) -
Bark of Passiflora edulis Treatment Stimulates Antioxidant Capacity, and Reduces Dyslipidemia and Body Fat in db/db Mice
by: Marielle Fernanda Panelli, et al.
Published: (2018-09-01) -
Oral ingestion of Shiikuwasha extract suppresses diabetes progression in db/db mice by preserving β-cell mass
by: Megumi Kaji, et al.
Published: (2024-01-01)