Verteporfin-Loaded Mesoporous Silica Nanoparticles’ Topical Applications Inhibit Mouse Melanoma Lymphangiogenesis and Micrometastasis In Vivo

Verteporfin-Loaded Mesoporous Silica Nanoparticles’ Topical Applications Inhibit Mouse Melanoma Lymphangiogenesis and Micrometastasis In Vivo

Photodynamic therapy (PDT) has been pointed out as a candidate for improving melanoma treatment. Nanotechnology application in PDT has increased its efficacy by reducing side effects. Herein, mesoporous silica nanoparticles (MSNs) conjugated with verteporfin (Ver-MSNs), in use with PDT, were adminis...

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Bibliographic Details
Main Authors: Nausicaa Clemente, Ivana Miletto, Enrica Gianotti, Maurizio Sabbatini, Marco Invernizzi, Leonardo Marchese, Umberto Dianzani, Filippo Renò
Format: Article
Language:English
Published: MDPI AG 2021-12-01
Series:International Journal of Molecular Sciences
Subjects:
melanoma
lymphoangiogenesis
micrometastasis
photodynamic therapy
verteporfin
mesoporous silica nanoparticles
Online Access:https://www.mdpi.com/1422-0067/22/24/13443

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