Validation of miRNAs as diagnostic and prognostic biomarkers, and possible therapeutic targets in medullary thyroid cancers

Validation of miRNAs as diagnostic and prognostic biomarkers, and possible therapeutic targets in medullary thyroid cancers

IntroductionMedullary thyroid cancer (MTC) is a rare type of neuroendocrine tumor that produces a hormone called calcitonin (CT). Thyroidectomy is the preferred treatment for MTC, as chemotherapy has been shown to have limited effectiveness. Targeted therapy approaches are currently being used for p...

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Bibliographic Details
Main Authors: Alberto Mondin, Loris Bertazza, Susi Barollo, Maria Chiara Pedron, Jacopo Manso, Ilaria Piva, Daniela Basso, Isabella Merante Boschin, Maurizio Iacobone, Raffaele Pezzani, Caterina Mian, Simona Censi
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-06-01
Series:Frontiers in Endocrinology
Subjects:
thyroid
medullary thyroid cancer
miR-21
PDCD4
miRNA silencing
Online Access:https://www.frontiersin.org/articles/10.3389/fendo.2023.1151583/full

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