Antimicrobial Efficacy of 2.5% Sodium Hypochlorite, 2% Chlorhexidine, and 1.5% Hydrogen Peroxide on Enterococcus Faecalis in Pulpectomy of Necrotic Primary Teeth
Introduction: The success of the endodontic treatment is closely associated with eliminating endodontic microbiota especially bacteria like Enterococcus Faecalis (E. Faecalis). Irrigation solutions are suggested for this purpose but there are contraries regarding irrigations and their concentrations...
| Main Authors: | , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Mashhad University of Medical Sciences
2021-06-01
|
| Series: | Journal of Dental Materials and Techniques |
| Subjects: | |
| Online Access: | https://jdmt.mums.ac.ir/article_18112_6bf01baf1b7c4ae1b1c746ad9ffbbb49.pdf |
| _version_ | 1823937794475556864 |
|---|---|
| author | Iman Parisay Maryam Talebi Shamimeh Asadi Ali Sharif moghadam Mohammad Hossein Nikbakht |
| author_facet | Iman Parisay Maryam Talebi Shamimeh Asadi Ali Sharif moghadam Mohammad Hossein Nikbakht |
| author_sort | Iman Parisay |
| collection | DOAJ |
| description | Introduction: The success of the endodontic treatment is closely associated with eliminating endodontic microbiota especially bacteria like Enterococcus Faecalis (E. Faecalis). Irrigation solutions are suggested for this purpose but there are contraries regarding irrigations and their concentrations. This study aimed to compare antibacterial efficacy of irrigations including 2.5% Sodium hypochlorite (NaOCl), 2% Chlorhexidine (CHX), and 1.5% Hydrogen peroxide (H2O2). Methods: Fifty deciduous human extracted teeth were divided into 3 groups of 15 teeth, 2.5% NaOCl, 2% CHX, 1.5% H2O2, and 5 teeth in the negative control group. Later, root canals were inoculated by E. Faecalis. After cleaning and shaping, we irrigated the root canals of the teeth in each group with NaOCl, CHX, and H2O2. Samples were obtained again and sent for microbiological evaluation. Wilcoxon signed-rank test, Paired sample T-test, and Kruskal–Wallis were used to analyze data. Results: All 3 groups showed significant bacterial reduction (p <0.05). NaOCl and CHX showed no significant difference (P=0.415). But the reduction of these 2 groups was higher than H2O2 (p Conclusions: 2.5% NaOCl and 2% Chlorhexidine showed considerable efficacy against E. Faecalis while 1.5% Hydrogen peroxide was not able to eradicate all of E. Faecalis colonies. Hence, NaOCl and CHX solutions can be used for decontamination of infected root canals |
| first_indexed | 2024-12-17T02:36:02Z |
| format | Article |
| id | doaj.art-9e3892a7d8ae4243aaeb3e5d4b2f0115 |
| institution | Directory Open Access Journal |
| issn | 2322-4150 2252-0317 |
| language | English |
| last_indexed | 2024-12-17T02:36:02Z |
| publishDate | 2021-06-01 |
| publisher | Mashhad University of Medical Sciences |
| record_format | Article |
| series | Journal of Dental Materials and Techniques |
| spelling | doaj.art-9e3892a7d8ae4243aaeb3e5d4b2f01152022-12-21T22:06:50ZengMashhad University of Medical SciencesJournal of Dental Materials and Techniques2322-41502252-03172021-06-011029410110.22038/jdmt.2021.55209.142018112Antimicrobial Efficacy of 2.5% Sodium Hypochlorite, 2% Chlorhexidine, and 1.5% Hydrogen Peroxide on Enterococcus Faecalis in Pulpectomy of Necrotic Primary TeethIman Parisay0Maryam Talebi1Shamimeh Asadi2Ali Sharif moghadam3Mohammad Hossein Nikbakht4Department of Pediatric Dentistry, Faculty of Dentistry, Mashhad University of Medical Sciences, Mashhad, IranDepartment of Pediatric Dentistry, Faculty of Dentistry, Mashhad University of Medical Sciences, Mashhad, IranDental Student, Student Research Committee, Dental school, Mashhad University of Medical Sciences, Mashhad, IranDepartment of Orthodontics, Faculty of Dentistry, North Khorasan University of Medical Sciences, Bojnord, IranDental Student, Student Research Committee, Dental school, Isfahan University of Medical Sciences, Isfahan, IranIntroduction: The success of the endodontic treatment is closely associated with eliminating endodontic microbiota especially bacteria like Enterococcus Faecalis (E. Faecalis). Irrigation solutions are suggested for this purpose but there are contraries regarding irrigations and their concentrations. This study aimed to compare antibacterial efficacy of irrigations including 2.5% Sodium hypochlorite (NaOCl), 2% Chlorhexidine (CHX), and 1.5% Hydrogen peroxide (H2O2). Methods: Fifty deciduous human extracted teeth were divided into 3 groups of 15 teeth, 2.5% NaOCl, 2% CHX, 1.5% H2O2, and 5 teeth in the negative control group. Later, root canals were inoculated by E. Faecalis. After cleaning and shaping, we irrigated the root canals of the teeth in each group with NaOCl, CHX, and H2O2. Samples were obtained again and sent for microbiological evaluation. Wilcoxon signed-rank test, Paired sample T-test, and Kruskal–Wallis were used to analyze data. Results: All 3 groups showed significant bacterial reduction (p <0.05). NaOCl and CHX showed no significant difference (P=0.415). But the reduction of these 2 groups was higher than H2O2 (p Conclusions: 2.5% NaOCl and 2% Chlorhexidine showed considerable efficacy against E. Faecalis while 1.5% Hydrogen peroxide was not able to eradicate all of E. Faecalis colonies. Hence, NaOCl and CHX solutions can be used for decontamination of infected root canalshttps://jdmt.mums.ac.ir/article_18112_6bf01baf1b7c4ae1b1c746ad9ffbbb49.pdfsodium hypochloritechlorhexidinehydrogen peroxideprimary teethpulpectomyenterococcus faecalis |
| spellingShingle | Iman Parisay Maryam Talebi Shamimeh Asadi Ali Sharif moghadam Mohammad Hossein Nikbakht Antimicrobial Efficacy of 2.5% Sodium Hypochlorite, 2% Chlorhexidine, and 1.5% Hydrogen Peroxide on Enterococcus Faecalis in Pulpectomy of Necrotic Primary Teeth Journal of Dental Materials and Techniques sodium hypochlorite chlorhexidine hydrogen peroxide primary teeth pulpectomy enterococcus faecalis |
| title | Antimicrobial Efficacy of 2.5% Sodium Hypochlorite, 2% Chlorhexidine, and 1.5% Hydrogen Peroxide on Enterococcus Faecalis in Pulpectomy of Necrotic Primary Teeth |
| title_full | Antimicrobial Efficacy of 2.5% Sodium Hypochlorite, 2% Chlorhexidine, and 1.5% Hydrogen Peroxide on Enterococcus Faecalis in Pulpectomy of Necrotic Primary Teeth |
| title_fullStr | Antimicrobial Efficacy of 2.5% Sodium Hypochlorite, 2% Chlorhexidine, and 1.5% Hydrogen Peroxide on Enterococcus Faecalis in Pulpectomy of Necrotic Primary Teeth |
| title_full_unstemmed | Antimicrobial Efficacy of 2.5% Sodium Hypochlorite, 2% Chlorhexidine, and 1.5% Hydrogen Peroxide on Enterococcus Faecalis in Pulpectomy of Necrotic Primary Teeth |
| title_short | Antimicrobial Efficacy of 2.5% Sodium Hypochlorite, 2% Chlorhexidine, and 1.5% Hydrogen Peroxide on Enterococcus Faecalis in Pulpectomy of Necrotic Primary Teeth |
| title_sort | antimicrobial efficacy of 2 5 sodium hypochlorite 2 chlorhexidine and 1 5 hydrogen peroxide on enterococcus faecalis in pulpectomy of necrotic primary teeth |
| topic | sodium hypochlorite chlorhexidine hydrogen peroxide primary teeth pulpectomy enterococcus faecalis |
| url | https://jdmt.mums.ac.ir/article_18112_6bf01baf1b7c4ae1b1c746ad9ffbbb49.pdf |
| work_keys_str_mv | AT imanparisay antimicrobialefficacyof25sodiumhypochlorite2chlorhexidineand15hydrogenperoxideonenterococcusfaecalisinpulpectomyofnecroticprimaryteeth AT maryamtalebi antimicrobialefficacyof25sodiumhypochlorite2chlorhexidineand15hydrogenperoxideonenterococcusfaecalisinpulpectomyofnecroticprimaryteeth AT shamimehasadi antimicrobialefficacyof25sodiumhypochlorite2chlorhexidineand15hydrogenperoxideonenterococcusfaecalisinpulpectomyofnecroticprimaryteeth AT alisharifmoghadam antimicrobialefficacyof25sodiumhypochlorite2chlorhexidineand15hydrogenperoxideonenterococcusfaecalisinpulpectomyofnecroticprimaryteeth AT mohammadhosseinnikbakht antimicrobialefficacyof25sodiumhypochlorite2chlorhexidineand15hydrogenperoxideonenterococcusfaecalisinpulpectomyofnecroticprimaryteeth |