Lumbar Spinal Stenosis Treatment: Is Surgery Better than Non-Surgical Treatments in Afro-Descendant Populations?
(1) Background: Limited data are available on lumbar spine stenosis management in sub-Saharan African populations and Afro-descendant patients are underrepresented in European and US clinical trials. We aimed to compare the clinical response between decompressive surgery and conservative treatments...
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| Format: | Article |
| Language: | English |
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MDPI AG
2022-12-01
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| Series: | Biomedicines |
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| Online Access: | https://www.mdpi.com/2227-9059/10/12/3144 |
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| author | Fabienne Louis-Sidney Jean-Florent Duby Aïssatou Signate Serge Arfi Michel De Bandt Benoit Suzon Philippe Cabre |
| author_facet | Fabienne Louis-Sidney Jean-Florent Duby Aïssatou Signate Serge Arfi Michel De Bandt Benoit Suzon Philippe Cabre |
| author_sort | Fabienne Louis-Sidney |
| collection | DOAJ |
| description | (1) Background: Limited data are available on lumbar spine stenosis management in sub-Saharan African populations and Afro-descendant patients are underrepresented in European and US clinical trials. We aimed to compare the clinical response between decompressive surgery and conservative treatments in a population of self-reported Afro-Caribbean patients with lumbar spine stenosis over a 2-year follow-up period. (2) Methods: Prospective cohort of 137 self-reported Afro Caribbeans with lumbar spine stenosis based on clinical and radiological criteria. Patients were assigned to decompression surgery or to conservative treatments according to their outcome after a first course of steroid epidural injection and their preferences. The primary outcome was evolution of the Oswestry disability index at 3 months (3 M), 12 M, 18 M and 24 M follow-up. (3) Results: Decrease of ODI was significantly more important in the “decompression surgery” arm compared to “conservative treatment” arm at 3 M, 12 M and 18 M: −17.36 vs. 1.03 <i>p</i> < 10<sup>−4</sup>; −16.38 vs. −1.53 <i>p</i> = 0.0059 and −19.00 vs. −4.52 <i>p</i> = 0.021, respectively. No difference was reported at 24 M. (4) Conclusions: In this first comparative study between surgery and conservative treatments in an exclusively afro-descendant lumbar spine stenosis cohort, we report long term superiority of decompression surgery versus conservative treatments over an 18-month period. |
| first_indexed | 2024-03-09T17:18:27Z |
| format | Article |
| id | doaj.art-9e38a37b7623421da838a792a04f3c8a |
| institution | Directory Open Access Journal |
| issn | 2227-9059 |
| language | English |
| last_indexed | 2024-03-09T17:18:27Z |
| publishDate | 2022-12-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Biomedicines |
| spelling | doaj.art-9e38a37b7623421da838a792a04f3c8a2023-11-24T13:27:37ZengMDPI AGBiomedicines2227-90592022-12-011012314410.3390/biomedicines10123144Lumbar Spinal Stenosis Treatment: Is Surgery Better than Non-Surgical Treatments in Afro-Descendant Populations?Fabienne Louis-Sidney0Jean-Florent Duby1Aïssatou Signate2Serge Arfi3Michel De Bandt4Benoit Suzon5Philippe Cabre6Service de Rhumatologie, CHU de Fort de France, 97200 Fort de France, FranceService de Rhumatologie, CHU de Fort de France, 97200 Fort de France, FranceService de Neurologie, CHU de Fort de France, 97200 Fort de France, FranceService de Rhumatologie, CHU de Fort de France, 97200 Fort de France, FranceService de Rhumatologie, CHU de Fort de France, 97200 Fort de France, FranceService de Médecine Interne, CHU de Fort de France, 97200 Fort de France, FranceService de Neurologie, CHU de Fort de France, 97200 Fort de France, France(1) Background: Limited data are available on lumbar spine stenosis management in sub-Saharan African populations and Afro-descendant patients are underrepresented in European and US clinical trials. We aimed to compare the clinical response between decompressive surgery and conservative treatments in a population of self-reported Afro-Caribbean patients with lumbar spine stenosis over a 2-year follow-up period. (2) Methods: Prospective cohort of 137 self-reported Afro Caribbeans with lumbar spine stenosis based on clinical and radiological criteria. Patients were assigned to decompression surgery or to conservative treatments according to their outcome after a first course of steroid epidural injection and their preferences. The primary outcome was evolution of the Oswestry disability index at 3 months (3 M), 12 M, 18 M and 24 M follow-up. (3) Results: Decrease of ODI was significantly more important in the “decompression surgery” arm compared to “conservative treatment” arm at 3 M, 12 M and 18 M: −17.36 vs. 1.03 <i>p</i> < 10<sup>−4</sup>; −16.38 vs. −1.53 <i>p</i> = 0.0059 and −19.00 vs. −4.52 <i>p</i> = 0.021, respectively. No difference was reported at 24 M. (4) Conclusions: In this first comparative study between surgery and conservative treatments in an exclusively afro-descendant lumbar spine stenosis cohort, we report long term superiority of decompression surgery versus conservative treatments over an 18-month period.https://www.mdpi.com/2227-9059/10/12/3144lumbar spine stenosissurgeryconservative treatmentsafro-descendants |
| spellingShingle | Fabienne Louis-Sidney Jean-Florent Duby Aïssatou Signate Serge Arfi Michel De Bandt Benoit Suzon Philippe Cabre Lumbar Spinal Stenosis Treatment: Is Surgery Better than Non-Surgical Treatments in Afro-Descendant Populations? Biomedicines lumbar spine stenosis surgery conservative treatments afro-descendants |
| title | Lumbar Spinal Stenosis Treatment: Is Surgery Better than Non-Surgical Treatments in Afro-Descendant Populations? |
| title_full | Lumbar Spinal Stenosis Treatment: Is Surgery Better than Non-Surgical Treatments in Afro-Descendant Populations? |
| title_fullStr | Lumbar Spinal Stenosis Treatment: Is Surgery Better than Non-Surgical Treatments in Afro-Descendant Populations? |
| title_full_unstemmed | Lumbar Spinal Stenosis Treatment: Is Surgery Better than Non-Surgical Treatments in Afro-Descendant Populations? |
| title_short | Lumbar Spinal Stenosis Treatment: Is Surgery Better than Non-Surgical Treatments in Afro-Descendant Populations? |
| title_sort | lumbar spinal stenosis treatment is surgery better than non surgical treatments in afro descendant populations |
| topic | lumbar spine stenosis surgery conservative treatments afro-descendants |
| url | https://www.mdpi.com/2227-9059/10/12/3144 |
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