Integrated smoking cessation and mood management following acute coronary syndrome: Protocol for the post-acute cardiac event smoking (PACES) trial
Abstract Background Approximately 400,000 people who smoke cigarettes survive Acute Coronary Syndrome (ACS; unstable angina, ST and non-ST elevation myocardial infarction) each year in the US. Continued smoking following ACS is an independent predictor of mortality. Depressed mood post-ACS is also p...
| Main Authors: | , , , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
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BMC
2023-05-01
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| Series: | Addiction Science & Clinical Practice |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s13722-023-00388-9 |
| _version_ | 1797827389427810304 |
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| author | Melissa Adkins-Hempel Sandra J. Japuntich Michelle Chrastek Shira Dunsiger Christopher E. Breault Woubeshet Ayenew Susan A. Everson-Rose Prabhjot S. Nijjar Beth C. Bock Wen-Chih Wu Michael D. Miedema Brett M. Carlson Andrew M. Busch |
| author_facet | Melissa Adkins-Hempel Sandra J. Japuntich Michelle Chrastek Shira Dunsiger Christopher E. Breault Woubeshet Ayenew Susan A. Everson-Rose Prabhjot S. Nijjar Beth C. Bock Wen-Chih Wu Michael D. Miedema Brett M. Carlson Andrew M. Busch |
| author_sort | Melissa Adkins-Hempel |
| collection | DOAJ |
| description | Abstract Background Approximately 400,000 people who smoke cigarettes survive Acute Coronary Syndrome (ACS; unstable angina, ST and non-ST elevation myocardial infarction) each year in the US. Continued smoking following ACS is an independent predictor of mortality. Depressed mood post-ACS is also predictive of mortality, and smokers with depressed mood are less likely to abstain from smoking following an ACS. A single, integrated treatment targeting depressed mood and smoking could be effective in reducing post-ACS mortality. Method/design The overall aim of the current study is to conduct a fully powered efficacy trial enrolling 324 smokers with ACS and randomizing them to 12 weeks of an integrated smoking cessation and mood management treatment [Behavioral Activation Treatment for Cardiac Smokers (BAT-CS)] or control (smoking cessation and general health education). Both groups will be offered 8 weeks of the nicotine patch if medically cleared. Counseling in both arms will be provided by tobacco treatment specialists. Follow-up assessments will be conducted at end-of-treatment (12-weeks) and 6, 9, and 12 months after hospital discharge. We will track major adverse cardiac events and all-cause mortality for 36 months post-discharge. Primary outcomes are depressed mood and biochemically validated 7-day point prevalence abstinence from smoking over 12 months. Discussion Results of this study will inform smoking cessation treatments post-ACS and provide unique data on the impact of depressed mood on success of post-ACS health behavior change attempts. Trial registration ClinicalTrials.gov, NCT03413423. Registered 29 January 2018. https://beta.clinicaltrials.gov/study/NCT03413423 . |
| first_indexed | 2024-04-09T12:47:29Z |
| format | Article |
| id | doaj.art-9e3c7f9c51de4221a7baabfaf6f7d1ca |
| institution | Directory Open Access Journal |
| issn | 1940-0640 |
| language | English |
| last_indexed | 2024-04-09T12:47:29Z |
| publishDate | 2023-05-01 |
| publisher | BMC |
| record_format | Article |
| series | Addiction Science & Clinical Practice |
| spelling | doaj.art-9e3c7f9c51de4221a7baabfaf6f7d1ca2023-05-14T11:23:53ZengBMCAddiction Science & Clinical Practice1940-06402023-05-0118111610.1186/s13722-023-00388-9Integrated smoking cessation and mood management following acute coronary syndrome: Protocol for the post-acute cardiac event smoking (PACES) trialMelissa Adkins-Hempel0Sandra J. Japuntich1Michelle Chrastek2Shira Dunsiger3Christopher E. Breault4Woubeshet Ayenew5Susan A. Everson-Rose6Prabhjot S. Nijjar7Beth C. Bock8Wen-Chih Wu9Michael D. Miedema10Brett M. Carlson11Andrew M. Busch12Behavioral Health Equity Research Group, Hennepin Healthcare Research InstituteBehavioral Health Equity Research Group, Hennepin Healthcare Research InstituteBehavioral Health Equity Research Group, Hennepin Healthcare Research InstituteDepartment of Behavioral and Social Sciences, Center for Health Promotion and Health Equity, School of Public Health, Brown UniversityCenter for Behavioral and Preventative Medicine, LifespanDivision of Cardiology, Department of Medicine, Hennepin HealthcareDivision of General Internal Medicine, Department of Medicine, University of MinnesotaCardiovascular Division, Department of Medicine, University of Minnesota Medical SchoolCenter for Behavioral and Preventative Medicine, LifespanDepartment of Epidemiology, School of Public Health, Brown UniversityMinneapolis Heart Institute and Minneapolis Heart Institute FoundationNorth Memorial Health Heart and Vascular CenterBehavioral Health Equity Research Group, Hennepin Healthcare Research InstituteAbstract Background Approximately 400,000 people who smoke cigarettes survive Acute Coronary Syndrome (ACS; unstable angina, ST and non-ST elevation myocardial infarction) each year in the US. Continued smoking following ACS is an independent predictor of mortality. Depressed mood post-ACS is also predictive of mortality, and smokers with depressed mood are less likely to abstain from smoking following an ACS. A single, integrated treatment targeting depressed mood and smoking could be effective in reducing post-ACS mortality. Method/design The overall aim of the current study is to conduct a fully powered efficacy trial enrolling 324 smokers with ACS and randomizing them to 12 weeks of an integrated smoking cessation and mood management treatment [Behavioral Activation Treatment for Cardiac Smokers (BAT-CS)] or control (smoking cessation and general health education). Both groups will be offered 8 weeks of the nicotine patch if medically cleared. Counseling in both arms will be provided by tobacco treatment specialists. Follow-up assessments will be conducted at end-of-treatment (12-weeks) and 6, 9, and 12 months after hospital discharge. We will track major adverse cardiac events and all-cause mortality for 36 months post-discharge. Primary outcomes are depressed mood and biochemically validated 7-day point prevalence abstinence from smoking over 12 months. Discussion Results of this study will inform smoking cessation treatments post-ACS and provide unique data on the impact of depressed mood on success of post-ACS health behavior change attempts. Trial registration ClinicalTrials.gov, NCT03413423. Registered 29 January 2018. https://beta.clinicaltrials.gov/study/NCT03413423 .https://doi.org/10.1186/s13722-023-00388-9SmokingDepressionBehavioral activationSecondary preventionAcute coronary syndromeCardiovascular disease |
| spellingShingle | Melissa Adkins-Hempel Sandra J. Japuntich Michelle Chrastek Shira Dunsiger Christopher E. Breault Woubeshet Ayenew Susan A. Everson-Rose Prabhjot S. Nijjar Beth C. Bock Wen-Chih Wu Michael D. Miedema Brett M. Carlson Andrew M. Busch Integrated smoking cessation and mood management following acute coronary syndrome: Protocol for the post-acute cardiac event smoking (PACES) trial Addiction Science & Clinical Practice Smoking Depression Behavioral activation Secondary prevention Acute coronary syndrome Cardiovascular disease |
| title | Integrated smoking cessation and mood management following acute coronary syndrome: Protocol for the post-acute cardiac event smoking (PACES) trial |
| title_full | Integrated smoking cessation and mood management following acute coronary syndrome: Protocol for the post-acute cardiac event smoking (PACES) trial |
| title_fullStr | Integrated smoking cessation and mood management following acute coronary syndrome: Protocol for the post-acute cardiac event smoking (PACES) trial |
| title_full_unstemmed | Integrated smoking cessation and mood management following acute coronary syndrome: Protocol for the post-acute cardiac event smoking (PACES) trial |
| title_short | Integrated smoking cessation and mood management following acute coronary syndrome: Protocol for the post-acute cardiac event smoking (PACES) trial |
| title_sort | integrated smoking cessation and mood management following acute coronary syndrome protocol for the post acute cardiac event smoking paces trial |
| topic | Smoking Depression Behavioral activation Secondary prevention Acute coronary syndrome Cardiovascular disease |
| url | https://doi.org/10.1186/s13722-023-00388-9 |
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