Long-term cardiovascular events in hypertensive patients: full report of the Korean Hypertension Cohort
Background/Aims This study evaluated the long-term cardiovascular complications among Korean patients with hypertension and compared them with that of controls without hypertension. Methods The Korean Hypertension Cohort (KHC) enrolled 11,043 patients with hypertension and followed them for more tha...
| Main Authors: | , , , , , , , , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
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The Korean Association of Internal Medicine
2023-01-01
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| Series: | The Korean Journal of Internal Medicine |
| Subjects: | |
| Online Access: | http://kjim.org/upload/pdf/kjim-2022-249.pdf |
| _version_ | 1797962582384967680 |
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| author | Jin Young Lee Jean Kyung Bak Mina Kim Ho-Gyun Shin Kyun-Ik Park Seung-Pyo Lee Hee-Sun Lee Ju-Yeun Lee Kwang-il Kim Si-Hyuck Kang Jang Hoon Lee Se Yong Jang Ju-Hee Lee Kye Hun Kim Jae Yeong Cho Jae-Hyeong Park Sue K. Park Hae-Young Lee |
| author_facet | Jin Young Lee Jean Kyung Bak Mina Kim Ho-Gyun Shin Kyun-Ik Park Seung-Pyo Lee Hee-Sun Lee Ju-Yeun Lee Kwang-il Kim Si-Hyuck Kang Jang Hoon Lee Se Yong Jang Ju-Hee Lee Kye Hun Kim Jae Yeong Cho Jae-Hyeong Park Sue K. Park Hae-Young Lee |
| author_sort | Jin Young Lee |
| collection | DOAJ |
| description | Background/Aims This study evaluated the long-term cardiovascular complications among Korean patients with hypertension and compared them with that of controls without hypertension. Methods The Korean Hypertension Cohort (KHC) enrolled 11,043 patients with hypertension and followed them for more than 10 years. Age- and sex-matched controls without hypertension were enrolled at a 1:10 ratio. We compared the incidence of cardiovascular events and death among patients and controls without hypertension. Results The mean age was 59 years, and 34.8% and 16.5% of the patients belonged to the high and moderate cardiovascular risk groups, respectively. During the 10-year follow-up, 1,591 cardiovascular events (14.4%) with 588 deaths (5.3%) occurred among patients with hypertension and 7,635 cardiovascular events (6.9%) with 4,826 deaths (4.4%) occurred among controls. Even the low-risk population with hypertension showed a higher cardiovascular event rate than the population without hypertension. Although blood pressure measurements in the clinic showed remarkable inaccuracy compared with those measured in the national health examinations, systolic blood pressure (SBP) ≥ 150 mmHg was significantly associated with a higher risk of cardiovascular events. Conclusions This long-term follow-up study confirmed the cardiovascular event rates among Korean hypertensive patients were substantial, reaching 15% in 10 years. SBP levels ≥ 150 mmHg were highly associated with occurrence of cardiovascular event rates. |
| first_indexed | 2024-04-11T01:15:26Z |
| format | Article |
| id | doaj.art-9e3d919767b54b22b1caba078e692b4f |
| institution | Directory Open Access Journal |
| issn | 1226-3303 2005-6648 |
| language | English |
| last_indexed | 2024-04-11T01:15:26Z |
| publishDate | 2023-01-01 |
| publisher | The Korean Association of Internal Medicine |
| record_format | Article |
| series | The Korean Journal of Internal Medicine |
| spelling | doaj.art-9e3d919767b54b22b1caba078e692b4f2023-01-04T03:50:21ZengThe Korean Association of Internal MedicineThe Korean Journal of Internal Medicine1226-33032005-66482023-01-01381566710.3904/kjim.2022.249170752Long-term cardiovascular events in hypertensive patients: full report of the Korean Hypertension CohortJin Young Lee0Jean Kyung Bak1Mina Kim2Ho-Gyun Shin3Kyun-Ik Park4Seung-Pyo Lee5Hee-Sun Lee6Ju-Yeun Lee7Kwang-il Kim8Si-Hyuck Kang9Jang Hoon Lee10Se Yong Jang11Ju-Hee Lee12Kye Hun Kim13Jae Yeong Cho14Jae-Hyeong Park15Sue K. Park16Hae-Young Lee17 Department of Applied Statistics, Chung-Ang University, Seoul, Korea National Evidence-based Healthcare Collaborating Agency (NECA), Seoul, Korea Department of Applied Statistics, Chung-Ang University, Seoul, Korea National Evidence-based Healthcare Collaborating Agency (NECA), Seoul, Korea National Evidence-based Healthcare Collaborating Agency (NECA), Seoul, Korea Department of Internal Medicine, Seoul National University Hospital, Seoul, Korea Department of Internal Medicine, Seoul National University Hospital, Seoul, Korea College of Pharmacy, Seoul National University, Seoul, Korea Department of Internal Medicine, Seoul National University College of Medicine, Seoul, Korea Department of Internal Medicine, Seoul National University College of Medicine, Seoul, Korea Department of Internal Medicine, Kyungpook National University Hospital, School of Medicine, Kyungpook National University, Daegu, Korea Department of Internal Medicine, Kyungpook National University Hospital, School of Medicine, Kyungpook National University, Daegu, Korea Division of Cardiology, Department of Internal Medicine, Chungbuk National University Hospital, Chungbuk National University College of Medicine, Cheongju, Korea Department of Cardiovascular Medicine, Chonnam National University Hospital, Chonnam National University Medical School, Gwangju, Korea Department of Internal Medicine, Chungnam National University College of Medicine, Daejeon, Korea Department of Internal Medicine, Chungnam National University College of Medicine, Daejeon, Korea Department of Preventive Medicine, Seoul National University College of Medicine, Seoul, Korea Department of Internal Medicine, Seoul National University Hospital, Seoul, KoreaBackground/Aims This study evaluated the long-term cardiovascular complications among Korean patients with hypertension and compared them with that of controls without hypertension. Methods The Korean Hypertension Cohort (KHC) enrolled 11,043 patients with hypertension and followed them for more than 10 years. Age- and sex-matched controls without hypertension were enrolled at a 1:10 ratio. We compared the incidence of cardiovascular events and death among patients and controls without hypertension. Results The mean age was 59 years, and 34.8% and 16.5% of the patients belonged to the high and moderate cardiovascular risk groups, respectively. During the 10-year follow-up, 1,591 cardiovascular events (14.4%) with 588 deaths (5.3%) occurred among patients with hypertension and 7,635 cardiovascular events (6.9%) with 4,826 deaths (4.4%) occurred among controls. Even the low-risk population with hypertension showed a higher cardiovascular event rate than the population without hypertension. Although blood pressure measurements in the clinic showed remarkable inaccuracy compared with those measured in the national health examinations, systolic blood pressure (SBP) ≥ 150 mmHg was significantly associated with a higher risk of cardiovascular events. Conclusions This long-term follow-up study confirmed the cardiovascular event rates among Korean hypertensive patients were substantial, reaching 15% in 10 years. SBP levels ≥ 150 mmHg were highly associated with occurrence of cardiovascular event rates.http://kjim.org/upload/pdf/kjim-2022-249.pdfhypertensionblood pressurecardiovascular diseases |
| spellingShingle | Jin Young Lee Jean Kyung Bak Mina Kim Ho-Gyun Shin Kyun-Ik Park Seung-Pyo Lee Hee-Sun Lee Ju-Yeun Lee Kwang-il Kim Si-Hyuck Kang Jang Hoon Lee Se Yong Jang Ju-Hee Lee Kye Hun Kim Jae Yeong Cho Jae-Hyeong Park Sue K. Park Hae-Young Lee Long-term cardiovascular events in hypertensive patients: full report of the Korean Hypertension Cohort The Korean Journal of Internal Medicine hypertension blood pressure cardiovascular diseases |
| title | Long-term cardiovascular events in hypertensive patients: full report of the Korean Hypertension Cohort |
| title_full | Long-term cardiovascular events in hypertensive patients: full report of the Korean Hypertension Cohort |
| title_fullStr | Long-term cardiovascular events in hypertensive patients: full report of the Korean Hypertension Cohort |
| title_full_unstemmed | Long-term cardiovascular events in hypertensive patients: full report of the Korean Hypertension Cohort |
| title_short | Long-term cardiovascular events in hypertensive patients: full report of the Korean Hypertension Cohort |
| title_sort | long term cardiovascular events in hypertensive patients full report of the korean hypertension cohort |
| topic | hypertension blood pressure cardiovascular diseases |
| url | http://kjim.org/upload/pdf/kjim-2022-249.pdf |
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