Prevalence of upper digestive endoscopy and gastric histopathology findings in morbidly obese patients
CONTEXT: The prevalence of obesity has been increasing in modern society. Roux-en-y gastric bypass is a bariatric surgery that involves the exclusion of significant part of the stomach. Atrophy, intestinal metaplasia and gastric cancer have been associated with infection by Helicobacter pylori. OBJE...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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Instituto Brasileiro de Estudos e Pesquisas de Gastroenterologia (IBEPEGE)
2012-03-01
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| Series: | Arquivos de Gastroenterologia |
| Subjects: | |
| Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0004-28032012000100009&lng=en&tlng=en |
| _version_ | 1819264931858481152 |
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| author | Judite Dietz Jane Maria Ulbrich-Kulcynski Katia Elisabete Pires Souto Nelson Guardiola Meinhardt |
| author_facet | Judite Dietz Jane Maria Ulbrich-Kulcynski Katia Elisabete Pires Souto Nelson Guardiola Meinhardt |
| author_sort | Judite Dietz |
| collection | DOAJ |
| description | CONTEXT: The prevalence of obesity has been increasing in modern society. Roux-en-y gastric bypass is a bariatric surgery that involves the exclusion of significant part of the stomach. Atrophy, intestinal metaplasia and gastric cancer have been associated with infection by Helicobacter pylori. OBJECTIVES: To evaluate the presence of endoscopy findings and histological changes in morbid obese patients for the presence of inflammatory cells, inflammatory activity, lymphoid hyperplasia, H. pylori infection, atrophy and intestinal metaplasia in the gastric mucosa. METHODS: Upper digestive endoscopy and gastric histopathological were studied in 126 obese patients in the preoperative evaluation for bariatric surgery. RESULTS: Upper digestive endoscopy abnormalities were diagnosed in 73/126 (57.9%) patients. In three patients (2.4%) the upper gastrointestinal endoscopy diagnosed gastric ulcer and one patient (0.8%) had duodenal ulcer. The histopathological from gastric biopsies of these obese patients showed 65.1% of mucosa inflammation, inflammatory activity in 50.0%, infection by H. pylori in 53.2%, lymphoid hyperplasia in 50.0% and atrophy and/or intestinal metaplasia in 16.7%. CONCLUSIONS: In present study, with routine preoperative upper gastrointestinal endoscopy and histopathological examination, were detected 57.9% patients with endoscopy abnormalities, high prevalence of infection by H. pylori (53%) and 16.7% of gastric atrophy and/or intestinal metaplasia. |
| first_indexed | 2024-12-23T20:37:20Z |
| format | Article |
| id | doaj.art-9e3ee67634da4bf681a60d0fefc07441 |
| institution | Directory Open Access Journal |
| issn | 1678-4219 |
| language | English |
| last_indexed | 2024-12-23T20:37:20Z |
| publishDate | 2012-03-01 |
| publisher | Instituto Brasileiro de Estudos e Pesquisas de Gastroenterologia (IBEPEGE) |
| record_format | Article |
| series | Arquivos de Gastroenterologia |
| spelling | doaj.art-9e3ee67634da4bf681a60d0fefc074412022-12-21T17:32:03ZengInstituto Brasileiro de Estudos e Pesquisas de Gastroenterologia (IBEPEGE)Arquivos de Gastroenterologia1678-42192012-03-01491525510.1590/S0004-28032012000100009S0004-28032012000100009Prevalence of upper digestive endoscopy and gastric histopathology findings in morbidly obese patientsJudite Dietz0Jane Maria Ulbrich-Kulcynski1Katia Elisabete Pires Souto2Nelson Guardiola Meinhardt3HNSCUniversidade Federal do Rio Grande do SulHNSCHNSCCONTEXT: The prevalence of obesity has been increasing in modern society. Roux-en-y gastric bypass is a bariatric surgery that involves the exclusion of significant part of the stomach. Atrophy, intestinal metaplasia and gastric cancer have been associated with infection by Helicobacter pylori. OBJECTIVES: To evaluate the presence of endoscopy findings and histological changes in morbid obese patients for the presence of inflammatory cells, inflammatory activity, lymphoid hyperplasia, H. pylori infection, atrophy and intestinal metaplasia in the gastric mucosa. METHODS: Upper digestive endoscopy and gastric histopathological were studied in 126 obese patients in the preoperative evaluation for bariatric surgery. RESULTS: Upper digestive endoscopy abnormalities were diagnosed in 73/126 (57.9%) patients. In three patients (2.4%) the upper gastrointestinal endoscopy diagnosed gastric ulcer and one patient (0.8%) had duodenal ulcer. The histopathological from gastric biopsies of these obese patients showed 65.1% of mucosa inflammation, inflammatory activity in 50.0%, infection by H. pylori in 53.2%, lymphoid hyperplasia in 50.0% and atrophy and/or intestinal metaplasia in 16.7%. CONCLUSIONS: In present study, with routine preoperative upper gastrointestinal endoscopy and histopathological examination, were detected 57.9% patients with endoscopy abnormalities, high prevalence of infection by H. pylori (53%) and 16.7% of gastric atrophy and/or intestinal metaplasia.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0004-28032012000100009&lng=en&tlng=enObesidade mórbidaDerivação gástricaEndoscopia gastrointestinalInfecções por helicobacter |
| spellingShingle | Judite Dietz Jane Maria Ulbrich-Kulcynski Katia Elisabete Pires Souto Nelson Guardiola Meinhardt Prevalence of upper digestive endoscopy and gastric histopathology findings in morbidly obese patients Arquivos de Gastroenterologia Obesidade mórbida Derivação gástrica Endoscopia gastrointestinal Infecções por helicobacter |
| title | Prevalence of upper digestive endoscopy and gastric histopathology findings in morbidly obese patients |
| title_full | Prevalence of upper digestive endoscopy and gastric histopathology findings in morbidly obese patients |
| title_fullStr | Prevalence of upper digestive endoscopy and gastric histopathology findings in morbidly obese patients |
| title_full_unstemmed | Prevalence of upper digestive endoscopy and gastric histopathology findings in morbidly obese patients |
| title_short | Prevalence of upper digestive endoscopy and gastric histopathology findings in morbidly obese patients |
| title_sort | prevalence of upper digestive endoscopy and gastric histopathology findings in morbidly obese patients |
| topic | Obesidade mórbida Derivação gástrica Endoscopia gastrointestinal Infecções por helicobacter |
| url | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0004-28032012000100009&lng=en&tlng=en |
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