Protein Disulphide Isomerase A1 Is Involved in the Regulation of Breast Cancer Cell Adhesion and Transmigration via Lung Microvascular Endothelial Cells

Protein Disulphide Isomerase A1 Is Involved in the Regulation of Breast Cancer Cell Adhesion and Transmigration via Lung Microvascular Endothelial Cells

Cancer cell cross-talk with the host endothelium plays a crucial role in metastasis, but the underlying mechanisms are still not fully understood. We studied the involvement of protein disulphide isomerase A1 (PDIA1) in human breast cancer cell (MCF-7 and MDA-MB-231) adhesion and transendothelial mi...

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Bibliographic Details
Main Authors: Marta Stojak, Magdalena Milczarek, Anna Kurpinska, Joanna Suraj-Prazmowska, Patrycja Kaczara, Kamila Wojnar-Lason, Joanna Banach, Martyna Stachowicz-Suhs, Joanna Rossowska, Ivars Kalviņš, Joanna Wietrzyk, Stefan Chlopicki
Format: Article
Language:English
Published: MDPI AG 2020-10-01
Series:Cancers
Subjects:
protein disulphide isomerase A1
adhesion
transendothelial migration
disulphide exchange
Online Access:https://www.mdpi.com/2072-6694/12/10/2850

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