Clinical observation of POEMS-syndrome: difficulties of diagnosis and treatment

Abstract:POEMS syndrome is a rare systemic disease that manifests with the following main symptoms: polyneuropathy, organomegaly, endocrinopathy, paraproteinemia, skin changes. A clinical case of POEMS syndrome in a 42-year-old patient is presented. The diagnosis was verified after the appearance an...

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Main Authors: T.B. Bender, Yu.N. Bykov, Yu.N. Vasiliev, A.S. Bokhna, S.V. Vasilkova, N.I. Merinova
Format: Article
Language:English
Published: Ministry of Health of the Russian Federation, Irkutsk State Medical University 2022-12-01
Series:Байкальский медицинский журнал
Subjects:
Online Access:https://www.bmjour.ru/jour/article/view/6
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author T.B. Bender
Yu.N. Bykov
Yu.N. Vasiliev
A.S. Bokhna
S.V. Vasilkova
N.I. Merinova
N.I. Merinova
author_facet T.B. Bender
Yu.N. Bykov
Yu.N. Vasiliev
A.S. Bokhna
S.V. Vasilkova
N.I. Merinova
N.I. Merinova
author_sort T.B. Bender
collection DOAJ
description Abstract:POEMS syndrome is a rare systemic disease that manifests with the following main symptoms: polyneuropathy, organomegaly, endocrinopathy, paraproteinemia, skin changes. A clinical case of POEMS syndrome in a 42-year-old patient is presented. The diagnosis was verified after the appearance and increase of extraneural symptoms, such as severe edema, respiratory failure, endocrinopathy, hepatosplenomegaly, lymphadenopathy. Additional patient examinations have been done and typical for this disease paraproteinemia has been identified. A course of specific therapy was undertaken in the hematology department, a positive effect was noted. Due to multisystem organ damage, there may be a variety of onset of the disease, which makes it difficult to correctly diagnose and prescribe appropriate therapy.
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spelling doaj.art-9e5003d21b0a4122b1be01c22dd8b0bf2024-01-01T12:18:05ZengMinistry of Health of the Russian Federation, Irkutsk State Medical UniversityБайкальский медицинский журнал2949-07152022-12-0111576310.57256/2949-0715-2022-1-57-633Clinical observation of POEMS-syndrome: difficulties of diagnosis and treatmentT.B. Bender0Yu.N. Bykov1Yu.N. Vasiliev2A.S. Bokhna3S.V. Vasilkova4N.I. Merinova5N.I. Merinova6Иркутский государственный медицинский университетИркутский государственный медицинский университетИркутский государственный медицинский университетИркутский государственный медицинский университетИркутский государственный медицинский университетИркутский государственный медицинский университетИркутский государственный медицинский университетAbstract:POEMS syndrome is a rare systemic disease that manifests with the following main symptoms: polyneuropathy, organomegaly, endocrinopathy, paraproteinemia, skin changes. A clinical case of POEMS syndrome in a 42-year-old patient is presented. The diagnosis was verified after the appearance and increase of extraneural symptoms, such as severe edema, respiratory failure, endocrinopathy, hepatosplenomegaly, lymphadenopathy. Additional patient examinations have been done and typical for this disease paraproteinemia has been identified. A course of specific therapy was undertaken in the hematology department, a positive effect was noted. Due to multisystem organ damage, there may be a variety of onset of the disease, which makes it difficult to correctly diagnose and prescribe appropriate therapy.https://www.bmjour.ru/jour/article/view/6рoems-синдромпарапротеинемияполинейропатияорганомегалия
spellingShingle T.B. Bender
Yu.N. Bykov
Yu.N. Vasiliev
A.S. Bokhna
S.V. Vasilkova
N.I. Merinova
N.I. Merinova
Clinical observation of POEMS-syndrome: difficulties of diagnosis and treatment
Байкальский медицинский журнал
рoems-синдром
парапротеинемия
полинейропатия
органомегалия
title Clinical observation of POEMS-syndrome: difficulties of diagnosis and treatment
title_full Clinical observation of POEMS-syndrome: difficulties of diagnosis and treatment
title_fullStr Clinical observation of POEMS-syndrome: difficulties of diagnosis and treatment
title_full_unstemmed Clinical observation of POEMS-syndrome: difficulties of diagnosis and treatment
title_short Clinical observation of POEMS-syndrome: difficulties of diagnosis and treatment
title_sort clinical observation of poems syndrome difficulties of diagnosis and treatment
topic рoems-синдром
парапротеинемия
полинейропатия
органомегалия
url https://www.bmjour.ru/jour/article/view/6
work_keys_str_mv AT tbbender clinicalobservationofpoemssyndromedifficultiesofdiagnosisandtreatment
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AT yunvasiliev clinicalobservationofpoemssyndromedifficultiesofdiagnosisandtreatment
AT asbokhna clinicalobservationofpoemssyndromedifficultiesofdiagnosisandtreatment
AT svvasilkova clinicalobservationofpoemssyndromedifficultiesofdiagnosisandtreatment
AT nimerinova clinicalobservationofpoemssyndromedifficultiesofdiagnosisandtreatment
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