Clinical observation of POEMS-syndrome: difficulties of diagnosis and treatment
Abstract:POEMS syndrome is a rare systemic disease that manifests with the following main symptoms: polyneuropathy, organomegaly, endocrinopathy, paraproteinemia, skin changes. A clinical case of POEMS syndrome in a 42-year-old patient is presented. The diagnosis was verified after the appearance an...
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| Format: | Article |
| Language: | English |
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Ministry of Health of the Russian Federation, Irkutsk State Medical University
2022-12-01
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| Series: | Байкальский медицинский журнал |
| Subjects: | |
| Online Access: | https://www.bmjour.ru/jour/article/view/6 |
| _version_ | 1826914631924318208 |
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| author | T.B. Bender Yu.N. Bykov Yu.N. Vasiliev A.S. Bokhna S.V. Vasilkova N.I. Merinova N.I. Merinova |
| author_facet | T.B. Bender Yu.N. Bykov Yu.N. Vasiliev A.S. Bokhna S.V. Vasilkova N.I. Merinova N.I. Merinova |
| author_sort | T.B. Bender |
| collection | DOAJ |
| description | Abstract:POEMS syndrome is a rare systemic disease that manifests with the following main symptoms: polyneuropathy, organomegaly, endocrinopathy, paraproteinemia, skin changes. A clinical case of POEMS syndrome in a 42-year-old patient is presented. The diagnosis was verified after the appearance and increase of extraneural symptoms, such as severe edema, respiratory failure, endocrinopathy, hepatosplenomegaly, lymphadenopathy. Additional patient examinations have been done and typical for this disease paraproteinemia has been identified. A course of specific therapy was undertaken in the hematology department, a positive effect was noted. Due to multisystem organ damage, there may be a variety of onset of the disease, which makes it difficult to correctly diagnose and prescribe appropriate therapy. |
| first_indexed | 2024-03-08T18:08:49Z |
| format | Article |
| id | doaj.art-9e5003d21b0a4122b1be01c22dd8b0bf |
| institution | Directory Open Access Journal |
| issn | 2949-0715 |
| language | English |
| last_indexed | 2025-02-17T11:48:01Z |
| publishDate | 2022-12-01 |
| publisher | Ministry of Health of the Russian Federation, Irkutsk State Medical University |
| record_format | Article |
| series | Байкальский медицинский журнал |
| spelling | doaj.art-9e5003d21b0a4122b1be01c22dd8b0bf2024-12-28T06:09:11ZengMinistry of Health of the Russian Federation, Irkutsk State Medical UniversityБайкальский медицинский журнал2949-07152022-12-0111576310.57256/2949-0715-2022-1-57-633Clinical observation of POEMS-syndrome: difficulties of diagnosis and treatmentT.B. Bender0Yu.N. Bykov1Yu.N. Vasiliev2A.S. Bokhna3S.V. Vasilkova4N.I. Merinova5N.I. Merinova6Irkutsk State Medical UniversityИркутский государственный медицинский университетIrkutsk State Medical UniversityIrkutsk Regional Clinical HospitalIrkutsk State Medical UniversityIrkutsk State Medical UniversityIrkutsk State Medical UniversityAbstract:POEMS syndrome is a rare systemic disease that manifests with the following main symptoms: polyneuropathy, organomegaly, endocrinopathy, paraproteinemia, skin changes. A clinical case of POEMS syndrome in a 42-year-old patient is presented. The diagnosis was verified after the appearance and increase of extraneural symptoms, such as severe edema, respiratory failure, endocrinopathy, hepatosplenomegaly, lymphadenopathy. Additional patient examinations have been done and typical for this disease paraproteinemia has been identified. A course of specific therapy was undertaken in the hematology department, a positive effect was noted. Due to multisystem organ damage, there may be a variety of onset of the disease, which makes it difficult to correctly diagnose and prescribe appropriate therapy.https://www.bmjour.ru/jour/article/view/6poems-syndrome, paraproteinemia, polyneuropathy, organomegaly |
| spellingShingle | T.B. Bender Yu.N. Bykov Yu.N. Vasiliev A.S. Bokhna S.V. Vasilkova N.I. Merinova N.I. Merinova Clinical observation of POEMS-syndrome: difficulties of diagnosis and treatment Байкальский медицинский журнал poems-syndrome, paraproteinemia, polyneuropathy, organomegaly |
| title | Clinical observation of POEMS-syndrome: difficulties of diagnosis and treatment |
| title_full | Clinical observation of POEMS-syndrome: difficulties of diagnosis and treatment |
| title_fullStr | Clinical observation of POEMS-syndrome: difficulties of diagnosis and treatment |
| title_full_unstemmed | Clinical observation of POEMS-syndrome: difficulties of diagnosis and treatment |
| title_short | Clinical observation of POEMS-syndrome: difficulties of diagnosis and treatment |
| title_sort | clinical observation of poems syndrome difficulties of diagnosis and treatment |
| topic | poems-syndrome, paraproteinemia, polyneuropathy, organomegaly |
| url | https://www.bmjour.ru/jour/article/view/6 |
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