Synaptic Ribbon Active Zones in Cone Photoreceptors Operate Independently from One Another

Synaptic Ribbon Active Zones in Cone Photoreceptors Operate Independently from One Another

Cone photoreceptors depolarize in darkness to release glutamate-laden synaptic vesicles. Essential to release is the synaptic ribbon, a structure that helps organize active zones by clustering vesicles near proteins that mediate exocytosis, including voltage-gated Ca2+ channels. Cone terminals have...

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Bibliographic Details
Main Authors: Justin J. Grassmeyer, Wallace B. Thoreson
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-07-01
Series:Frontiers in Cellular Neuroscience
Subjects:
ribbon synapse
retina
exocytosis
calcium imaging
cone photoreceptor
active zone
Online Access:https://www.frontiersin.org/article/10.3389/fncel.2017.00198/full

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