1. ARTERIAL STIFFNESS IN MASKED HYPERTENSION AND TRUE HYPERTENSION

Background: Masked hypertension (MH) has been drawing attention recently because this condition is often seen in untreated and treated individuals and is associated with target organ damage and a poor cardiovascular prognosis. Arterial stiffness is associated with organ damage in patients with prima...

Full description

Bibliographic Details
Main Authors: Young-Soo Lee, Kee Sik Kim, Myung Jun Seung, Jung Hyun Kim, So-Yeon Kim, Jin-Bae Lee, Jae-Kean Ryu, Ji-Yong Choi, Kee-Sik Kim, Sung-Gug Chang
Format: Article
Language:English
Published: BMC 2009-10-01
Series:Artery Research
Online Access:https://www.atlantis-press.com/article/125925778/view
_version_ 1828802254939881472
author Young-Soo Lee
Kee Sik Kim
Myung Jun Seung
Jung Hyun Kim
So-Yeon Kim
Jin-Bae Lee
Jae-Kean Ryu
Ji-Yong Choi
Kee-Sik Kim
Sung-Gug Chang
author_facet Young-Soo Lee
Kee Sik Kim
Myung Jun Seung
Jung Hyun Kim
So-Yeon Kim
Jin-Bae Lee
Jae-Kean Ryu
Ji-Yong Choi
Kee-Sik Kim
Sung-Gug Chang
author_sort Young-Soo Lee
collection DOAJ
description Background: Masked hypertension (MH) has been drawing attention recently because this condition is often seen in untreated and treated individuals and is associated with target organ damage and a poor cardiovascular prognosis. Arterial stiffness is associated with organ damage in patients with primary hypertension. The aim of this study was to evaluate pulse wave velocity (PWV) in MH and true hypertension (TH). Methods: We enrolled 146 patients (mean age 47.9±13.9 yrs, male 78 (53.4 %)), who was recently diagnosed as hypertension. MH was defined as office normotension (systolic blood pressure(SBP)<140mmHg or diastolic blood pressure(DBP)<90mmHg)and ambulatory hypertension (daytime average SBP≥135 mmHg or DBP≥85 mmHg), and TH was defined as office hypertension (SBP≥140 mmHg or DBP≥90 mmHg) and ambulatory hypertension. We compared carotid-femoral, carotid-radial PWV and femoral-ankle PWV(cf/cr/faPWV), left ventricular mass index(LVMI) and left atrial volume index (LAVI) among normal control, MH and TH. Results: The MH group was the oldest. The crPWV, cfPWV and faPWV in TH and MH were significantly more increased compared it in normal control (p<0.0001). Also, the LVMI in MH was significantly higher compared to it in normal control (145.8±35.8mg vs 121.5±14.5mg, respectively)(p<0.05). Conclusion: The masked hypertension might be decreased arterial stiffness, which was similar to true hypertension. However, further larger study might be needed.
first_indexed 2024-12-12T07:00:48Z
format Article
id doaj.art-9e5be903d42c438cb227592534f3552a
institution Directory Open Access Journal
issn 1876-4401
language English
last_indexed 2024-12-12T07:00:48Z
publishDate 2009-10-01
publisher BMC
record_format Article
series Artery Research
spelling doaj.art-9e5be903d42c438cb227592534f3552a2022-12-22T00:33:51ZengBMCArtery Research1876-44012009-10-013310.1016/j.artres.2009.06.0131. ARTERIAL STIFFNESS IN MASKED HYPERTENSION AND TRUE HYPERTENSIONYoung-Soo LeeKee Sik KimMyung Jun SeungJung Hyun KimSo-Yeon KimJin-Bae LeeJae-Kean RyuJi-Yong ChoiKee-Sik KimSung-Gug ChangBackground: Masked hypertension (MH) has been drawing attention recently because this condition is often seen in untreated and treated individuals and is associated with target organ damage and a poor cardiovascular prognosis. Arterial stiffness is associated with organ damage in patients with primary hypertension. The aim of this study was to evaluate pulse wave velocity (PWV) in MH and true hypertension (TH). Methods: We enrolled 146 patients (mean age 47.9±13.9 yrs, male 78 (53.4 %)), who was recently diagnosed as hypertension. MH was defined as office normotension (systolic blood pressure(SBP)<140mmHg or diastolic blood pressure(DBP)<90mmHg)and ambulatory hypertension (daytime average SBP≥135 mmHg or DBP≥85 mmHg), and TH was defined as office hypertension (SBP≥140 mmHg or DBP≥90 mmHg) and ambulatory hypertension. We compared carotid-femoral, carotid-radial PWV and femoral-ankle PWV(cf/cr/faPWV), left ventricular mass index(LVMI) and left atrial volume index (LAVI) among normal control, MH and TH. Results: The MH group was the oldest. The crPWV, cfPWV and faPWV in TH and MH were significantly more increased compared it in normal control (p<0.0001). Also, the LVMI in MH was significantly higher compared to it in normal control (145.8±35.8mg vs 121.5±14.5mg, respectively)(p<0.05). Conclusion: The masked hypertension might be decreased arterial stiffness, which was similar to true hypertension. However, further larger study might be needed.https://www.atlantis-press.com/article/125925778/view
spellingShingle Young-Soo Lee
Kee Sik Kim
Myung Jun Seung
Jung Hyun Kim
So-Yeon Kim
Jin-Bae Lee
Jae-Kean Ryu
Ji-Yong Choi
Kee-Sik Kim
Sung-Gug Chang
1. ARTERIAL STIFFNESS IN MASKED HYPERTENSION AND TRUE HYPERTENSION
Artery Research
title 1. ARTERIAL STIFFNESS IN MASKED HYPERTENSION AND TRUE HYPERTENSION
title_full 1. ARTERIAL STIFFNESS IN MASKED HYPERTENSION AND TRUE HYPERTENSION
title_fullStr 1. ARTERIAL STIFFNESS IN MASKED HYPERTENSION AND TRUE HYPERTENSION
title_full_unstemmed 1. ARTERIAL STIFFNESS IN MASKED HYPERTENSION AND TRUE HYPERTENSION
title_short 1. ARTERIAL STIFFNESS IN MASKED HYPERTENSION AND TRUE HYPERTENSION
title_sort 1 arterial stiffness in masked hypertension and true hypertension
url https://www.atlantis-press.com/article/125925778/view
work_keys_str_mv AT youngsoolee 1arterialstiffnessinmaskedhypertensionandtruehypertension
AT keesikkim 1arterialstiffnessinmaskedhypertensionandtruehypertension
AT myungjunseung 1arterialstiffnessinmaskedhypertensionandtruehypertension
AT junghyunkim 1arterialstiffnessinmaskedhypertensionandtruehypertension
AT soyeonkim 1arterialstiffnessinmaskedhypertensionandtruehypertension
AT jinbaelee 1arterialstiffnessinmaskedhypertensionandtruehypertension
AT jaekeanryu 1arterialstiffnessinmaskedhypertensionandtruehypertension
AT jiyongchoi 1arterialstiffnessinmaskedhypertensionandtruehypertension
AT keesikkim 1arterialstiffnessinmaskedhypertensionandtruehypertension
AT sunggugchang 1arterialstiffnessinmaskedhypertensionandtruehypertension