Genome instability and loss of protein homeostasis: converging paths to neurodegeneration?

Genome instability and loss of protein homeostasis are hallmark events of age-related diseases that include neurodegeneration. Several neurodegenerative diseases, such as Alzheimer's disease, Parkinson's disease, Huntington's disease and amyotrophic lateral sclerosis are characterized...

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Bibliographic Details
Main Authors: Anna Ainslie, Wouter Huiting, Lara Barazzuol, Steven Bergink
Format: Article
Language:English
Published: The Royal Society 2021-04-01
Series:Open Biology
Subjects:
Online Access:https://royalsocietypublishing.org/doi/10.1098/rsob.200296