The link between airway reflux and non-acid reflux in children: a review
Objective: Airway reflux, a member of extra-esophageal reflux, has been linked to countless respiratory pathologies amongst children. The advent of novel instrumentation has enabled the discovery of non-acid reflux which was postulated as the main culprit of airway reflux. The objective of this revi...
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| Format: | Article |
| Language: | English |
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Elsevier
2023-03-01
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| Series: | Brazilian Journal of Otorhinolaryngology |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S1808869422000738 |
| _version_ | 1827978361954107392 |
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| author | Jeyasakthy Saniasiaya Jeyanthi Kulasegarah |
| author_facet | Jeyasakthy Saniasiaya Jeyanthi Kulasegarah |
| author_sort | Jeyasakthy Saniasiaya |
| collection | DOAJ |
| description | Objective: Airway reflux, a member of extra-esophageal reflux, has been linked to countless respiratory pathologies amongst children. The advent of novel instrumentation has enabled the discovery of non-acid reflux which was postulated as the main culprit of airway reflux. The objective of this review is to outline the association between non-acid reflux and airway reflux in children. Methods: A comprehensive review of recent literature on non-acid reflux and airway reflux in children was conducted. Studies ranged from January 2010 till November 2021 were searched over a period of a month: December 2021. Results: A total of eleven studies were identified. All studies included in this review revealed a strong link between non-acid reflux and airway reflux in children. 6 of the included studies are prospective studies, 3 retrospective studies, 1 cross-section study, and type of study was not mentioned in 1 study. The most common reported respiratory manifestation of non-acid reflux in children was chronic cough (7 studies). Predominant non-acid reflux was noted in 4 studies. The total number of children in each study ranges from 21 to 150 patients. MII-pH study was carried out in all studies included as a diagnostic tool for reflux investigation. Conclusion: Non-acid reflux is the culprit behind airway reflux as well as other myriads of extra-esophageal manifestations in children. Multicentre international studies with a standardized protocol could improve scientific knowledge in managing non-acid reflux in airway reflux amongst children. |
| first_indexed | 2024-04-09T21:20:48Z |
| format | Article |
| id | doaj.art-9e62f603ec694ce28e06d4987ffcf3fc |
| institution | Directory Open Access Journal |
| issn | 1808-8694 |
| language | English |
| last_indexed | 2024-04-09T21:20:48Z |
| publishDate | 2023-03-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Brazilian Journal of Otorhinolaryngology |
| spelling | doaj.art-9e62f603ec694ce28e06d4987ffcf3fc2023-03-28T06:45:31ZengElsevierBrazilian Journal of Otorhinolaryngology1808-86942023-03-01892329338The link between airway reflux and non-acid reflux in children: a reviewJeyasakthy Saniasiaya0Jeyanthi Kulasegarah1Corresponding author.; University of Malaya, Faculty of Medicine, Department of Otorhinolaryngology, Wilayah Persekutuan Kuala Lumpur, MalaysiaUniversity of Malaya, Faculty of Medicine, Department of Otorhinolaryngology, Wilayah Persekutuan Kuala Lumpur, MalaysiaObjective: Airway reflux, a member of extra-esophageal reflux, has been linked to countless respiratory pathologies amongst children. The advent of novel instrumentation has enabled the discovery of non-acid reflux which was postulated as the main culprit of airway reflux. The objective of this review is to outline the association between non-acid reflux and airway reflux in children. Methods: A comprehensive review of recent literature on non-acid reflux and airway reflux in children was conducted. Studies ranged from January 2010 till November 2021 were searched over a period of a month: December 2021. Results: A total of eleven studies were identified. All studies included in this review revealed a strong link between non-acid reflux and airway reflux in children. 6 of the included studies are prospective studies, 3 retrospective studies, 1 cross-section study, and type of study was not mentioned in 1 study. The most common reported respiratory manifestation of non-acid reflux in children was chronic cough (7 studies). Predominant non-acid reflux was noted in 4 studies. The total number of children in each study ranges from 21 to 150 patients. MII-pH study was carried out in all studies included as a diagnostic tool for reflux investigation. Conclusion: Non-acid reflux is the culprit behind airway reflux as well as other myriads of extra-esophageal manifestations in children. Multicentre international studies with a standardized protocol could improve scientific knowledge in managing non-acid reflux in airway reflux amongst children.http://www.sciencedirect.com/science/article/pii/S1808869422000738Gastroesophageal refluxLaryngopharyngeal refluxAirway refluxNon-acid refluxChildren |
| spellingShingle | Jeyasakthy Saniasiaya Jeyanthi Kulasegarah The link between airway reflux and non-acid reflux in children: a review Brazilian Journal of Otorhinolaryngology Gastroesophageal reflux Laryngopharyngeal reflux Airway reflux Non-acid reflux Children |
| title | The link between airway reflux and non-acid reflux in children: a review |
| title_full | The link between airway reflux and non-acid reflux in children: a review |
| title_fullStr | The link between airway reflux and non-acid reflux in children: a review |
| title_full_unstemmed | The link between airway reflux and non-acid reflux in children: a review |
| title_short | The link between airway reflux and non-acid reflux in children: a review |
| title_sort | link between airway reflux and non acid reflux in children a review |
| topic | Gastroesophageal reflux Laryngopharyngeal reflux Airway reflux Non-acid reflux Children |
| url | http://www.sciencedirect.com/science/article/pii/S1808869422000738 |
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