Clinical and Laboratory Predictors of Long-Term Outcomes after Catheter Ablation for a Ventricular Electrical Storm
Background. Ventricular electrical storm (VES) is characterized by the occurrence of multiple episodes of sustained ventricular arrhythmias (VA) over a short period of time. Radiofrequency ablation (RFA) has been reported as an effective treatment in patients with ventricular tachycardia (VT). Objec...
| Main Authors: | , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Hindawi-Wiley
2024-01-01
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| Series: | Journal of Interventional Cardiology |
| Online Access: | http://dx.doi.org/10.1155/2024/5524668 |
| _version_ | 1797316070192709632 |
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| author | Grzegorz Sławiński Maja Hawryszko Julia Dyda-Kristowska Tomasz Królak Maciej Kempa Dariusz Świetlik Dariusz Kozłowski Ludmiła Daniłowicz-Szymanowicz Ewa Lewicka |
| author_facet | Grzegorz Sławiński Maja Hawryszko Julia Dyda-Kristowska Tomasz Królak Maciej Kempa Dariusz Świetlik Dariusz Kozłowski Ludmiła Daniłowicz-Szymanowicz Ewa Lewicka |
| author_sort | Grzegorz Sławiński |
| collection | DOAJ |
| description | Background. Ventricular electrical storm (VES) is characterized by the occurrence of multiple episodes of sustained ventricular arrhythmias (VA) over a short period of time. Radiofrequency ablation (RFA) has been reported as an effective treatment in patients with ventricular tachycardia (VT). Objective. The aim of the present study was to indicate the short-term and long-term predictors of recurrent VA after RFA was performed due to VES. Methods. A retrospective, single-centre study included patients, who had undergone RFA due to VT between 2012 and 2021. In terms of the short-term (at the end of RFA) effectiveness of RFA, the following scenarios were distinguished: complete success: inability to induce any VT; partial success: absence of clinical VT; failure: inducible clinical VT. In terms of the long-term (12 months) effectiveness of RFA, the following scenarios were distinguished: effective ablation: no recurrence of any VT; partially successful ablation: VT recurrence; ineffective ablation: VES recurrence. Results. The study included 62 patients. Complete short-term RFA success was obtained in 77.4% of patients. The estimated cumulative VT-free survival and VES-free survival were, respectively, 28% and 33% at the 12-month follow-up. Ischemic cardiomyopathy and complete short-term RFA success were predictors of long-term RFA efficacy. Neutrophil to lymphocyte ratio (NLR) and GFR <60 mL/min/1.73 m2 were associated with VES recurrence. NLR ≥2.95 predicted VT and/or VES recurrence with a sensitivity of 66.7% and specificity of 72.2%. Conclusion. Ischemic cardiomyopathy and short-term complete success of RFA were predictors of no VES recurrence during the 12-month follow-up, while NLR and GFR <60 ml/min/1.73 m2 were associated with VES relapse. |
| first_indexed | 2024-03-08T03:13:58Z |
| format | Article |
| id | doaj.art-9e63876c5a0f4432b4db9578b8875f8c |
| institution | Directory Open Access Journal |
| issn | 1540-8183 |
| language | English |
| last_indexed | 2024-03-08T03:13:58Z |
| publishDate | 2024-01-01 |
| publisher | Hindawi-Wiley |
| record_format | Article |
| series | Journal of Interventional Cardiology |
| spelling | doaj.art-9e63876c5a0f4432b4db9578b8875f8c2024-02-13T00:00:01ZengHindawi-WileyJournal of Interventional Cardiology1540-81832024-01-01202410.1155/2024/5524668Clinical and Laboratory Predictors of Long-Term Outcomes after Catheter Ablation for a Ventricular Electrical StormGrzegorz Sławiński0Maja Hawryszko1Julia Dyda-Kristowska2Tomasz Królak3Maciej Kempa4Dariusz Świetlik5Dariusz Kozłowski6Ludmiła Daniłowicz-Szymanowicz7Ewa Lewicka8Department of Cardiology and ElectrotherapyDepartment of Cardiology and ElectrotherapyDepartment of Cardiology and ElectrotherapyDepartment of Cardiology and ElectrotherapyDepartment of Cardiology and ElectrotherapyDivision of Biostatistics and Neural NetworksDepartment of Cardiology and ElectrotherapyDepartment of Cardiology and ElectrotherapyDepartment of Cardiology and ElectrotherapyBackground. Ventricular electrical storm (VES) is characterized by the occurrence of multiple episodes of sustained ventricular arrhythmias (VA) over a short period of time. Radiofrequency ablation (RFA) has been reported as an effective treatment in patients with ventricular tachycardia (VT). Objective. The aim of the present study was to indicate the short-term and long-term predictors of recurrent VA after RFA was performed due to VES. Methods. A retrospective, single-centre study included patients, who had undergone RFA due to VT between 2012 and 2021. In terms of the short-term (at the end of RFA) effectiveness of RFA, the following scenarios were distinguished: complete success: inability to induce any VT; partial success: absence of clinical VT; failure: inducible clinical VT. In terms of the long-term (12 months) effectiveness of RFA, the following scenarios were distinguished: effective ablation: no recurrence of any VT; partially successful ablation: VT recurrence; ineffective ablation: VES recurrence. Results. The study included 62 patients. Complete short-term RFA success was obtained in 77.4% of patients. The estimated cumulative VT-free survival and VES-free survival were, respectively, 28% and 33% at the 12-month follow-up. Ischemic cardiomyopathy and complete short-term RFA success were predictors of long-term RFA efficacy. Neutrophil to lymphocyte ratio (NLR) and GFR <60 mL/min/1.73 m2 were associated with VES recurrence. NLR ≥2.95 predicted VT and/or VES recurrence with a sensitivity of 66.7% and specificity of 72.2%. Conclusion. Ischemic cardiomyopathy and short-term complete success of RFA were predictors of no VES recurrence during the 12-month follow-up, while NLR and GFR <60 ml/min/1.73 m2 were associated with VES relapse.http://dx.doi.org/10.1155/2024/5524668 |
| spellingShingle | Grzegorz Sławiński Maja Hawryszko Julia Dyda-Kristowska Tomasz Królak Maciej Kempa Dariusz Świetlik Dariusz Kozłowski Ludmiła Daniłowicz-Szymanowicz Ewa Lewicka Clinical and Laboratory Predictors of Long-Term Outcomes after Catheter Ablation for a Ventricular Electrical Storm Journal of Interventional Cardiology |
| title | Clinical and Laboratory Predictors of Long-Term Outcomes after Catheter Ablation for a Ventricular Electrical Storm |
| title_full | Clinical and Laboratory Predictors of Long-Term Outcomes after Catheter Ablation for a Ventricular Electrical Storm |
| title_fullStr | Clinical and Laboratory Predictors of Long-Term Outcomes after Catheter Ablation for a Ventricular Electrical Storm |
| title_full_unstemmed | Clinical and Laboratory Predictors of Long-Term Outcomes after Catheter Ablation for a Ventricular Electrical Storm |
| title_short | Clinical and Laboratory Predictors of Long-Term Outcomes after Catheter Ablation for a Ventricular Electrical Storm |
| title_sort | clinical and laboratory predictors of long term outcomes after catheter ablation for a ventricular electrical storm |
| url | http://dx.doi.org/10.1155/2024/5524668 |
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