Scientific Opinion on Flavouring Group Evaluation 210 Revision 2 (FGE.210Rev2): Consideration of genotoxic potential for α,β‐unsaturated alicyclic ketones and precursors from chemical subgroup 2.4 of FGE.19
Abstract Safety Authority was requested to evaluate the genotoxic potential of 14 flavouring substances in Flavouring Group Evaluation 210 (FGE.210). In FGE.210, the Panel concluded that the genotoxic potential could not be ruled out for any of the flavouring substances. In FGE.210 Revision1, the Pa...
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| Format: | Article |
| Language: | English |
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Wiley
2015-07-01
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| Series: | EFSA Journal |
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| Online Access: | https://doi.org/10.2903/j.efsa.2015.4172 |
| _version_ | 1818948721732222976 |
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| author | EFSA Panel on Food Contact Materials, Enzymes, Flavourings and Processing Aids (CEF) |
| author_facet | EFSA Panel on Food Contact Materials, Enzymes, Flavourings and Processing Aids (CEF) |
| author_sort | EFSA Panel on Food Contact Materials, Enzymes, Flavourings and Processing Aids (CEF) |
| collection | DOAJ |
| description | Abstract Safety Authority was requested to evaluate the genotoxic potential of 14 flavouring substances in Flavouring Group Evaluation 210 (FGE.210). In FGE.210, the Panel concluded that the genotoxic potential could not be ruled out for any of the flavouring substances. In FGE.210 Revision1, the Panel concluded that the concern for genotoxic potential is ruled out for eight substances [FL‐no: 02.105, 07.007, 07.009, 07.011, 07.036, 07.088, 07.091 and 07.170] while for allyl a‐ionone [FL‐no: 07.061], for a‐damascone [FL‐no: 07.134] and four structurally related substances [FL‐no: 07.130, 07.225, 07.226 and 07.231] the concern for genotoxicity remains and additional data were requested. The Flavour Industry has submitted additional genotoxicity data for allyl a‐ionone [FL‐no: 07.061], that are evaluated in the present revision of FGE.210 (Revision 2). Based on these new data the Panel concluded that the genotoxicity concern for allyl a‐ionone [FL‐no: 07.061] can be ruled out. For a‐damascone [FL‐no: 07.134] and the four structurally related substances [FL‐no: 07.130, 07.225, 07.226 and 07.231] additional genotoxicity data are still required. |
| first_indexed | 2024-12-20T08:51:18Z |
| format | Article |
| id | doaj.art-9e63a7b6dd69449c8389c604936d48d3 |
| institution | Directory Open Access Journal |
| issn | 1831-4732 |
| language | English |
| last_indexed | 2024-12-20T08:51:18Z |
| publishDate | 2015-07-01 |
| publisher | Wiley |
| record_format | Article |
| series | EFSA Journal |
| spelling | doaj.art-9e63a7b6dd69449c8389c604936d48d32022-12-21T19:46:07ZengWileyEFSA Journal1831-47322015-07-01137n/an/a10.2903/j.efsa.2015.4172Scientific Opinion on Flavouring Group Evaluation 210 Revision 2 (FGE.210Rev2): Consideration of genotoxic potential for α,β‐unsaturated alicyclic ketones and precursors from chemical subgroup 2.4 of FGE.19EFSA Panel on Food Contact Materials, Enzymes, Flavourings and Processing Aids (CEF)Abstract Safety Authority was requested to evaluate the genotoxic potential of 14 flavouring substances in Flavouring Group Evaluation 210 (FGE.210). In FGE.210, the Panel concluded that the genotoxic potential could not be ruled out for any of the flavouring substances. In FGE.210 Revision1, the Panel concluded that the concern for genotoxic potential is ruled out for eight substances [FL‐no: 02.105, 07.007, 07.009, 07.011, 07.036, 07.088, 07.091 and 07.170] while for allyl a‐ionone [FL‐no: 07.061], for a‐damascone [FL‐no: 07.134] and four structurally related substances [FL‐no: 07.130, 07.225, 07.226 and 07.231] the concern for genotoxicity remains and additional data were requested. The Flavour Industry has submitted additional genotoxicity data for allyl a‐ionone [FL‐no: 07.061], that are evaluated in the present revision of FGE.210 (Revision 2). Based on these new data the Panel concluded that the genotoxicity concern for allyl a‐ionone [FL‐no: 07.061] can be ruled out. For a‐damascone [FL‐no: 07.134] and the four structurally related substances [FL‐no: 07.130, 07.225, 07.226 and 07.231] additional genotoxicity data are still required.https://doi.org/10.2903/j.efsa.2015.4172αβ‐unsaturated alicyclic ketonesflavouring substancessafety evaluationFGE.210subgroup 2.4 |
| spellingShingle | EFSA Panel on Food Contact Materials, Enzymes, Flavourings and Processing Aids (CEF) Scientific Opinion on Flavouring Group Evaluation 210 Revision 2 (FGE.210Rev2): Consideration of genotoxic potential for α,β‐unsaturated alicyclic ketones and precursors from chemical subgroup 2.4 of FGE.19 EFSA Journal α β‐unsaturated alicyclic ketones flavouring substances safety evaluation FGE.210 subgroup 2.4 |
| title | Scientific Opinion on Flavouring Group Evaluation 210 Revision 2 (FGE.210Rev2): Consideration of genotoxic potential for α,β‐unsaturated alicyclic ketones and precursors from chemical subgroup 2.4 of FGE.19 |
| title_full | Scientific Opinion on Flavouring Group Evaluation 210 Revision 2 (FGE.210Rev2): Consideration of genotoxic potential for α,β‐unsaturated alicyclic ketones and precursors from chemical subgroup 2.4 of FGE.19 |
| title_fullStr | Scientific Opinion on Flavouring Group Evaluation 210 Revision 2 (FGE.210Rev2): Consideration of genotoxic potential for α,β‐unsaturated alicyclic ketones and precursors from chemical subgroup 2.4 of FGE.19 |
| title_full_unstemmed | Scientific Opinion on Flavouring Group Evaluation 210 Revision 2 (FGE.210Rev2): Consideration of genotoxic potential for α,β‐unsaturated alicyclic ketones and precursors from chemical subgroup 2.4 of FGE.19 |
| title_short | Scientific Opinion on Flavouring Group Evaluation 210 Revision 2 (FGE.210Rev2): Consideration of genotoxic potential for α,β‐unsaturated alicyclic ketones and precursors from chemical subgroup 2.4 of FGE.19 |
| title_sort | scientific opinion on flavouring group evaluation 210 revision 2 fge 210rev2 consideration of genotoxic potential for α β unsaturated alicyclic ketones and precursors from chemical subgroup 2 4 of fge 19 |
| topic | α β‐unsaturated alicyclic ketones flavouring substances safety evaluation FGE.210 subgroup 2.4 |
| url | https://doi.org/10.2903/j.efsa.2015.4172 |
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