Identification of B-Cell Epitopes for Eliciting Neutralizing Antibodies against the SARS-CoV-2 Spike Protein through Bioinformatics and Monoclonal Antibody Targeting

Identification of B-Cell Epitopes for Eliciting Neutralizing Antibodies against the SARS-CoV-2 Spike Protein through Bioinformatics and Monoclonal Antibody Targeting

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has caused a global public health crisis. Effective COVID-19 vaccines developed by Pfizer-BioNTech, Moderna, and Astra Zeneca have made significant impacts in controlling the COVID-19 burden, especially in reducing the transmission of SARS...

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Bibliographic Details
Main Authors: Hui Xuan Lim, Malihe Masomian, Kanwal Khalid, Asqwin Uthaya Kumar, Paul A. MacAry, Chit Laa Poh
Format: Article
Language:English
Published: MDPI AG 2022-04-01
Series:International Journal of Molecular Sciences
Subjects:
B-cell epitope
vaccine
SARS-CoV-2
spike protein
Online Access:https://www.mdpi.com/1422-0067/23/8/4341

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