Kojic acid-derived tyrosinase inhibitors: synthesis and bioactivity

Kojic acid-derived tyrosinase inhibitors: synthesis and bioactivity

Tyrosinase is a key enzyme for melanin biosynthesis, catalyzing the oxidation of L-tyrosine to L-dopaquinone. The tyrosinase inhibition is an effective approach to control hyperpigmentation in human skin and enzymatic browning in fruits and vegetables. Kojic acid is a naturally-occurring tyrosinase...

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Bibliographic Details
Main Authors:	Seyedeh Mahdieh Hashemi, Saeed Emami
Format:	Article
Language:	English
Published:	Mazandaran University of Medical Sciences 2015-01-01
Series:	Pharmaceutical and Biomedical Research
Subjects:	Kojic acid 4H-pyran-4-one derivatives enzyme inhibitors structural modifications
Online Access:	http://pbr.mazums.ac.ir/browse.php?a_code=A-10-26-1&slc_lang=en&sid=1

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