Restricted Blood Flow Exercise in Sedentary, Overweight African-American Females May Increase Muscle Strength and Decrease Endothelial Function and Vascular Autoregulation
Objectives: Exercise with partially restricted blood flow is a low-load, low-intensity resistance training regimen which may have the potential to increase muscle strength in the obese, elderly and frail who are unable to do high-load training. Restricted blood flow exercise has also been shown to a...
| Main Authors: | , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Korean Pharmacopuncture Institute
2017-03-01
|
| Series: | Journal of Pharmacopuncture |
| Subjects: | |
| Online Access: | http://dx.doi.org/10.3831/KPI.2017.20.002 |
| _version_ | 1811289056909197312 |
|---|---|
| author | Vernon Bond Bryan Heath Curry Krishna Kumar Sudhakar Pemminati Vasavi Rakesh Gorantla Kishan Kadur Richard Mark Millis |
| author_facet | Vernon Bond Bryan Heath Curry Krishna Kumar Sudhakar Pemminati Vasavi Rakesh Gorantla Kishan Kadur Richard Mark Millis |
| author_sort | Vernon Bond |
| collection | DOAJ |
| description | Objectives: Exercise with partially restricted blood flow is a low-load, low-intensity resistance training regimen which may have the potential to increase muscle strength in the obese, elderly and frail who are unable to do high-load training. Restricted blood flow exercise has also been shown to affect blood vessel function variably and can, therefore, contribute to blood vessel dysfunction. This pilot study tests the hypothesis that unilateral resistance training of the leg extensors with partially restricted blood flow increases muscle strength and decreases vascular autoregulation. Methods: The subjects were nine normotensive, overweight, young adult African-Americans with low cardiorespiratory fitness who underwent unilateral training of the quadriceps’ femoris muscles with partially restricted blood flow at 30% of the 1-repetition maximum (1-RM) load for 3 weeks. The 1-RM load and post-occlusion blood flow to the lower leg (calf) were measured during reactive hyperemia. Results: The 1-RM load increased in the trained legs from 77 ± 3 to 84 ± 4 kg (P < 0.05) in the absence of a significant effect on the 1-RM load in the contralateral untrained legs (P > 0.1). Post-occlusion blood flow decreased significantly in the trained legs from 19 ± 2 to 13 ± 2 mL· min-1· dL-1 (P < 0.05) and marginally in the contralateral untrained legs from 18 ± 2 to 16 ± 1 mL· min-1· dL-1 (P = 0.09). Changes in post-occlusion blood flow to the skin overlying the trained and the contralateral untrained muscles were not significant. Conclusion: These results demonstrate that restricted blood flow exercise, which results in significant gains in muscle strength, may produce decrements in endothelial dysfunction and vascular autoregulation. Future studies should determine whether pharmacopuncture plays a role in treatments for such blood vessel dysfunction. |
| first_indexed | 2024-04-13T03:48:14Z |
| format | Article |
| id | doaj.art-9e68b901c8b847e59ef80cd57ee868cf |
| institution | Directory Open Access Journal |
| issn | 2093-6966 2234-6856 |
| language | English |
| last_indexed | 2024-04-13T03:48:14Z |
| publishDate | 2017-03-01 |
| publisher | Korean Pharmacopuncture Institute |
| record_format | Article |
| series | Journal of Pharmacopuncture |
| spelling | doaj.art-9e68b901c8b847e59ef80cd57ee868cf2022-12-22T03:03:56ZengKorean Pharmacopuncture InstituteJournal of Pharmacopuncture2093-69662234-68562017-03-01201232810.3831/KPI.2017.20.002DHOCBS_2017_v20n1_23Restricted Blood Flow Exercise in Sedentary, Overweight African-American Females May Increase Muscle Strength and Decrease Endothelial Function and Vascular AutoregulationVernon Bond0Bryan Heath Curry1Krishna Kumar2Sudhakar Pemminati3Vasavi Rakesh Gorantla4Kishan Kadur5Richard Mark Millis6Department of Recreation, Human Performance & Leisure Studies and Exercise Science & Human Nutrition Laboratory, Howard University Cancer Centre, Washington DC, United States of AmericaDepartment of Medicine, Division of Cardiology, Howard College of Medicine & Howard University Hospital, Washington DC, United States of AmericaDepartment of Pharmaceutical Sciences, Howard University Hospital, Washington DC, United States of AmericaDepartment of Medical Pharmacology, AUA College of Medicine & Manipal University, Antigua and BarbudaDepartment of Behavioural Sciences and Neuroscience, AUA College of Medicine, Antigua and BarbudaDepartment of Medical Physiology, AUA College of Medicine, Antigua and BarbudaDepartment of Medical Physiology, AUA College of Medicine, Antigua and BarbudaObjectives: Exercise with partially restricted blood flow is a low-load, low-intensity resistance training regimen which may have the potential to increase muscle strength in the obese, elderly and frail who are unable to do high-load training. Restricted blood flow exercise has also been shown to affect blood vessel function variably and can, therefore, contribute to blood vessel dysfunction. This pilot study tests the hypothesis that unilateral resistance training of the leg extensors with partially restricted blood flow increases muscle strength and decreases vascular autoregulation. Methods: The subjects were nine normotensive, overweight, young adult African-Americans with low cardiorespiratory fitness who underwent unilateral training of the quadriceps’ femoris muscles with partially restricted blood flow at 30% of the 1-repetition maximum (1-RM) load for 3 weeks. The 1-RM load and post-occlusion blood flow to the lower leg (calf) were measured during reactive hyperemia. Results: The 1-RM load increased in the trained legs from 77 ± 3 to 84 ± 4 kg (P < 0.05) in the absence of a significant effect on the 1-RM load in the contralateral untrained legs (P > 0.1). Post-occlusion blood flow decreased significantly in the trained legs from 19 ± 2 to 13 ± 2 mL· min-1· dL-1 (P < 0.05) and marginally in the contralateral untrained legs from 18 ± 2 to 16 ± 1 mL· min-1· dL-1 (P = 0.09). Changes in post-occlusion blood flow to the skin overlying the trained and the contralateral untrained muscles were not significant. Conclusion: These results demonstrate that restricted blood flow exercise, which results in significant gains in muscle strength, may produce decrements in endothelial dysfunction and vascular autoregulation. Future studies should determine whether pharmacopuncture plays a role in treatments for such blood vessel dysfunction.http://dx.doi.org/10.3831/KPI.2017.20.002Kaatsuquadriceps femorisresistance trainingskeletal muscle |
| spellingShingle | Vernon Bond Bryan Heath Curry Krishna Kumar Sudhakar Pemminati Vasavi Rakesh Gorantla Kishan Kadur Richard Mark Millis Restricted Blood Flow Exercise in Sedentary, Overweight African-American Females May Increase Muscle Strength and Decrease Endothelial Function and Vascular Autoregulation Journal of Pharmacopuncture Kaatsu quadriceps femoris resistance training skeletal muscle |
| title | Restricted Blood Flow Exercise in Sedentary, Overweight African-American Females May Increase Muscle Strength and Decrease Endothelial Function and Vascular Autoregulation |
| title_full | Restricted Blood Flow Exercise in Sedentary, Overweight African-American Females May Increase Muscle Strength and Decrease Endothelial Function and Vascular Autoregulation |
| title_fullStr | Restricted Blood Flow Exercise in Sedentary, Overweight African-American Females May Increase Muscle Strength and Decrease Endothelial Function and Vascular Autoregulation |
| title_full_unstemmed | Restricted Blood Flow Exercise in Sedentary, Overweight African-American Females May Increase Muscle Strength and Decrease Endothelial Function and Vascular Autoregulation |
| title_short | Restricted Blood Flow Exercise in Sedentary, Overweight African-American Females May Increase Muscle Strength and Decrease Endothelial Function and Vascular Autoregulation |
| title_sort | restricted blood flow exercise in sedentary overweight african american females may increase muscle strength and decrease endothelial function and vascular autoregulation |
| topic | Kaatsu quadriceps femoris resistance training skeletal muscle |
| url | http://dx.doi.org/10.3831/KPI.2017.20.002 |
| work_keys_str_mv | AT vernonbond restrictedbloodflowexerciseinsedentaryoverweightafricanamericanfemalesmayincreasemusclestrengthanddecreaseendothelialfunctionandvascularautoregulation AT bryanheathcurry restrictedbloodflowexerciseinsedentaryoverweightafricanamericanfemalesmayincreasemusclestrengthanddecreaseendothelialfunctionandvascularautoregulation AT krishnakumar restrictedbloodflowexerciseinsedentaryoverweightafricanamericanfemalesmayincreasemusclestrengthanddecreaseendothelialfunctionandvascularautoregulation AT sudhakarpemminati restrictedbloodflowexerciseinsedentaryoverweightafricanamericanfemalesmayincreasemusclestrengthanddecreaseendothelialfunctionandvascularautoregulation AT vasavirakeshgorantla restrictedbloodflowexerciseinsedentaryoverweightafricanamericanfemalesmayincreasemusclestrengthanddecreaseendothelialfunctionandvascularautoregulation AT kishankadur restrictedbloodflowexerciseinsedentaryoverweightafricanamericanfemalesmayincreasemusclestrengthanddecreaseendothelialfunctionandvascularautoregulation AT richardmarkmillis restrictedbloodflowexerciseinsedentaryoverweightafricanamericanfemalesmayincreasemusclestrengthanddecreaseendothelialfunctionandvascularautoregulation |