Value of Prophylactic Postoperative Antibiotic Therapy after Bimaxillary Orthognathic Surgery: A Clinical Trial
Introduction: Antibiotic therapy before or after orthognathic surgery is commonly recommended by surgeons to minimize the risk of wound infection. This article evaluates the value of Prophylactic antibiotic therapy in order to diminish the incidence of postoperative wound infection after orthognathi...
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| Format: | Article |
| Language: | English |
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Mashhad University of Medical Sciences
2014-10-01
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| Series: | Iranian Journal of Otorhinolaryngology |
| Subjects: | |
| Online Access: | http://ijorl.mums.ac.ir/pdf_2867_7ee427c6073720876d47aaaa2c27eaa7.html |
| _version_ | 1811277465176244224 |
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| author | Majid Eshghpour Amin Khajavi Mahmoud Bagheri Elham Banihashemi |
| author_facet | Majid Eshghpour Amin Khajavi Mahmoud Bagheri Elham Banihashemi |
| author_sort | Majid Eshghpour |
| collection | DOAJ |
| description | Introduction: Antibiotic therapy before or after orthognathic surgery is commonly recommended by surgeons to minimize the risk of wound infection. This article evaluates the value of Prophylactic antibiotic therapy in order to diminish the incidence of postoperative wound infection after orthognathic surgery. Materials and Methods: Fifty candidates for bimaxillary orthognathic surgery were divided into cases and controls. Cefazolin (1g) was administered intravenously to all participants 30 mins prior to surgery followed by a similar dose 4 hours later. Case-group patients ingested amoxicillin (500 mg) orally for 7 days after surgery. Postoperative wound infection was assessed using clinical features, and the P-value significance was set at P Results: Both groups were similar according to gender, age, and operating time. During the follow-up period no infection was observed in either the case or control group. Conclusion: The results of this study suggest that long-term postoperative antibiotic therapy is not essential for the prevention of postoperative infection, and that application of aseptic surgical technique and hygiene instruction after surgery are sufficient. |
| first_indexed | 2024-04-13T00:17:03Z |
| format | Article |
| id | doaj.art-9e6af51b0b6f482cbea60b5de07ca192 |
| institution | Directory Open Access Journal |
| issn | 2251-7251 2251-726X |
| language | English |
| last_indexed | 2024-04-13T00:17:03Z |
| publishDate | 2014-10-01 |
| publisher | Mashhad University of Medical Sciences |
| record_format | Article |
| series | Iranian Journal of Otorhinolaryngology |
| spelling | doaj.art-9e6af51b0b6f482cbea60b5de07ca1922022-12-22T03:10:55ZengMashhad University of Medical SciencesIranian Journal of Otorhinolaryngology2251-72512251-726X2014-10-0126772072102867Value of Prophylactic Postoperative Antibiotic Therapy after Bimaxillary Orthognathic Surgery: A Clinical TrialMajid Eshghpour0Amin Khajavi1Mahmoud Bagheri2Elham Banihashemi3Dental Research Center, Mashhad University of Medical Sciences, Mashhad, Iran.General Practitioner, Mashhad, Iran.General Practitioner, Mashhad, Iran.General Practitioner, Mashhad, Iran.Introduction: Antibiotic therapy before or after orthognathic surgery is commonly recommended by surgeons to minimize the risk of wound infection. This article evaluates the value of Prophylactic antibiotic therapy in order to diminish the incidence of postoperative wound infection after orthognathic surgery. Materials and Methods: Fifty candidates for bimaxillary orthognathic surgery were divided into cases and controls. Cefazolin (1g) was administered intravenously to all participants 30 mins prior to surgery followed by a similar dose 4 hours later. Case-group patients ingested amoxicillin (500 mg) orally for 7 days after surgery. Postoperative wound infection was assessed using clinical features, and the P-value significance was set at P Results: Both groups were similar according to gender, age, and operating time. During the follow-up period no infection was observed in either the case or control group. Conclusion: The results of this study suggest that long-term postoperative antibiotic therapy is not essential for the prevention of postoperative infection, and that application of aseptic surgical technique and hygiene instruction after surgery are sufficient.http://ijorl.mums.ac.ir/pdf_2867_7ee427c6073720876d47aaaa2c27eaa7.htmlAmoxicillinAntibiotic therapyOrthognathic surgeryPost-operative wound infection |
| spellingShingle | Majid Eshghpour Amin Khajavi Mahmoud Bagheri Elham Banihashemi Value of Prophylactic Postoperative Antibiotic Therapy after Bimaxillary Orthognathic Surgery: A Clinical Trial Iranian Journal of Otorhinolaryngology Amoxicillin Antibiotic therapy Orthognathic surgery Post-operative wound infection |
| title | Value of Prophylactic Postoperative Antibiotic Therapy after Bimaxillary Orthognathic Surgery: A Clinical Trial |
| title_full | Value of Prophylactic Postoperative Antibiotic Therapy after Bimaxillary Orthognathic Surgery: A Clinical Trial |
| title_fullStr | Value of Prophylactic Postoperative Antibiotic Therapy after Bimaxillary Orthognathic Surgery: A Clinical Trial |
| title_full_unstemmed | Value of Prophylactic Postoperative Antibiotic Therapy after Bimaxillary Orthognathic Surgery: A Clinical Trial |
| title_short | Value of Prophylactic Postoperative Antibiotic Therapy after Bimaxillary Orthognathic Surgery: A Clinical Trial |
| title_sort | value of prophylactic postoperative antibiotic therapy after bimaxillary orthognathic surgery a clinical trial |
| topic | Amoxicillin Antibiotic therapy Orthognathic surgery Post-operative wound infection |
| url | http://ijorl.mums.ac.ir/pdf_2867_7ee427c6073720876d47aaaa2c27eaa7.html |
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