Management of neurogenic bladder dysfunction in children update and recommendations on medical treatment
ABSTRACT Introduction: Defective closure of the neural tube affects different systems and generates sequelae, such as neurogenic bladder (NB). Myelomeningocele (MMC) represents the most frequent and most severe cause of NB in children. Damage of the renal parenchyma in children with NB acquired in...
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| Format: | Article |
| Language: | English |
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Sociedade Brasileira de Urologia
2022-01-01
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| Series: | International Brazilian Journal of Urology |
| Subjects: | |
| Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1677-55382022000100031&tlng=en |
| _version_ | 1819243578582368256 |
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| author | Cristian Sager Ubirajara Barroso Jr. José Murillo B. Netto Gabriela Retamal Edurne Ormaechea |
| author_facet | Cristian Sager Ubirajara Barroso Jr. José Murillo B. Netto Gabriela Retamal Edurne Ormaechea |
| author_sort | Cristian Sager |
| collection | DOAJ |
| description | ABSTRACT Introduction: Defective closure of the neural tube affects different systems and generates sequelae, such as neurogenic bladder (NB). Myelomeningocele (MMC) represents the most frequent and most severe cause of NB in children. Damage of the renal parenchyma in children with NB acquired in postnatal stages is preventable given adequate evaluation, follow-up and proactive management. The aim of this document is to update issues on medical management of neurogenic bladder in children. Materials and Methods: Five Pediatric Urologists joined a group of experts and reviewed all important issues on “Spina Bifida, Neurogenic Bladder in Children” and elaborated a draft of the document. All the members of the group focused on the same system of classification of the levels of evidence (GRADE system) in order to assess the literature and the recommendations. During the year 2020 the panel of experts has met virtually to review, discuss and write a consensus document. Results and Discussion: The panel addressed recommendations on up to date choice of diagnosis evaluation and therapies. Clean intermittent catheterization (CIC) should be implemented during the first days of life, and antimuscarinic drugs should be indicated upon results of urodynamic studies. When the patient becomes refractory to first-line therapy, receptor-selective pharmacotherapy is available nowadays, which leads to a reduction in reconstructive procedures, such as augmentation cystoplasty. |
| first_indexed | 2024-12-23T14:57:56Z |
| format | Article |
| id | doaj.art-9e6d18715404492380e3648ec94efdbc |
| institution | Directory Open Access Journal |
| issn | 1677-6119 |
| language | English |
| last_indexed | 2024-12-23T14:57:56Z |
| publishDate | 2022-01-01 |
| publisher | Sociedade Brasileira de Urologia |
| record_format | Article |
| series | International Brazilian Journal of Urology |
| spelling | doaj.art-9e6d18715404492380e3648ec94efdbc2022-12-21T17:42:42ZengSociedade Brasileira de UrologiaInternational Brazilian Journal of Urology1677-61192022-01-01481315110.1590/s1677-5538.ibju.2020.0989Management of neurogenic bladder dysfunction in children update and recommendations on medical treatmentCristian Sagerhttps://orcid.org/0000-0002-6884-8898Ubirajara Barroso Jr.José Murillo B. NettoGabriela RetamalEdurne OrmaecheaABSTRACT Introduction: Defective closure of the neural tube affects different systems and generates sequelae, such as neurogenic bladder (NB). Myelomeningocele (MMC) represents the most frequent and most severe cause of NB in children. Damage of the renal parenchyma in children with NB acquired in postnatal stages is preventable given adequate evaluation, follow-up and proactive management. The aim of this document is to update issues on medical management of neurogenic bladder in children. Materials and Methods: Five Pediatric Urologists joined a group of experts and reviewed all important issues on “Spina Bifida, Neurogenic Bladder in Children” and elaborated a draft of the document. All the members of the group focused on the same system of classification of the levels of evidence (GRADE system) in order to assess the literature and the recommendations. During the year 2020 the panel of experts has met virtually to review, discuss and write a consensus document. Results and Discussion: The panel addressed recommendations on up to date choice of diagnosis evaluation and therapies. Clean intermittent catheterization (CIC) should be implemented during the first days of life, and antimuscarinic drugs should be indicated upon results of urodynamic studies. When the patient becomes refractory to first-line therapy, receptor-selective pharmacotherapy is available nowadays, which leads to a reduction in reconstructive procedures, such as augmentation cystoplasty.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1677-55382022000100031&tlng=enUrinary Bladder, Neurogenictherapy [Subheading]Child |
| spellingShingle | Cristian Sager Ubirajara Barroso Jr. José Murillo B. Netto Gabriela Retamal Edurne Ormaechea Management of neurogenic bladder dysfunction in children update and recommendations on medical treatment International Brazilian Journal of Urology Urinary Bladder, Neurogenic therapy [Subheading] Child |
| title | Management of neurogenic bladder dysfunction in children update and recommendations on medical treatment |
| title_full | Management of neurogenic bladder dysfunction in children update and recommendations on medical treatment |
| title_fullStr | Management of neurogenic bladder dysfunction in children update and recommendations on medical treatment |
| title_full_unstemmed | Management of neurogenic bladder dysfunction in children update and recommendations on medical treatment |
| title_short | Management of neurogenic bladder dysfunction in children update and recommendations on medical treatment |
| title_sort | management of neurogenic bladder dysfunction in children update and recommendations on medical treatment |
| topic | Urinary Bladder, Neurogenic therapy [Subheading] Child |
| url | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1677-55382022000100031&tlng=en |
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