Modern methods of stimulation of angiogenesis in patients with critical limb ischemia (review)

The term "critical ischemia of extremities" (critical limb ischemia) was first introduced by P.R.F. Bell in 1982 to refer to a group of diseases accompanied by pain in the legs at rest, trophic ulcers and distal necroses of the lower limbs. Critical ischemia of the lower limbs is a conditi...

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Main Authors: I. A. Kryvoruchko, S. K.-T. Goni, M. S. Antonova, M. A. Sykal, U. M. Voronaja, M. A. Alexandrov, N. V. Lola
Format: Article
Language:English
Published: Kazimierz Wielki University 2017-04-01
Series:Journal of Education, Health and Sport
Subjects:
Online Access:http://www.ojs.ukw.edu.pl/index.php/johs/article/view/4464
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author I. A. Kryvoruchko
S. K.-T. Goni
M. S. Antonova
M. A. Sykal
U. M. Voronaja
M. A. Alexandrov
N. V. Lola
author_facet I. A. Kryvoruchko
S. K.-T. Goni
M. S. Antonova
M. A. Sykal
U. M. Voronaja
M. A. Alexandrov
N. V. Lola
author_sort I. A. Kryvoruchko
collection DOAJ
description The term "critical ischemia of extremities" (critical limb ischemia) was first introduced by P.R.F. Bell in 1982 to refer to a group of diseases accompanied by pain in the legs at rest, trophic ulcers and distal necroses of the lower limbs. Critical ischemia of the lower limbs is a condition of almost complete cessation of arterial blood flow to the tissues of the lower limbs. If the arterial blood supply is not improved, limb amputation becomes inevitable for all patients. Treatment of ischemia of the lower extremities should be complex and differentiated depending on the stage and features of the course of the disease. Modern approaches to the therapy of lower limb ischemia include conservative and surgical methods of treatment, all of which are aimed at improving blood flow in the affected limbs. In the article modern methods of stimulating angiogenesis in patients with lower limb ischemia and results are shown.
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spelling doaj.art-9e6deaf7199e4c13b48f023bd7b195982022-12-21T18:19:17ZengKazimierz Wielki UniversityJournal of Education, Health and Sport2391-83062017-04-017473374510.5281/zenodo.5833144237Modern methods of stimulation of angiogenesis in patients with critical limb ischemia (review)I. A. Kryvoruchko0S. K.-T. Goni1M. S. Antonova2M. A. Sykal3U. M. Voronaja4M. A. Alexandrov5N. V. Lola6Kharkov National Medical UniversityKharkov National Medical UniversityKharkov National Medical UniversityKharkov National Medical UniversityKharkov National Medical UniversityKharkov National Medical UniversityKharkov National Medical UniversityThe term "critical ischemia of extremities" (critical limb ischemia) was first introduced by P.R.F. Bell in 1982 to refer to a group of diseases accompanied by pain in the legs at rest, trophic ulcers and distal necroses of the lower limbs. Critical ischemia of the lower limbs is a condition of almost complete cessation of arterial blood flow to the tissues of the lower limbs. If the arterial blood supply is not improved, limb amputation becomes inevitable for all patients. Treatment of ischemia of the lower extremities should be complex and differentiated depending on the stage and features of the course of the disease. Modern approaches to the therapy of lower limb ischemia include conservative and surgical methods of treatment, all of which are aimed at improving blood flow in the affected limbs. In the article modern methods of stimulating angiogenesis in patients with lower limb ischemia and results are shown.http://www.ojs.ukw.edu.pl/index.php/johs/article/view/4464critical limb ischemia, cell therapy, gene therapy, angiogenesis stimulation
spellingShingle I. A. Kryvoruchko
S. K.-T. Goni
M. S. Antonova
M. A. Sykal
U. M. Voronaja
M. A. Alexandrov
N. V. Lola
Modern methods of stimulation of angiogenesis in patients with critical limb ischemia (review)
Journal of Education, Health and Sport
critical limb ischemia, cell therapy, gene therapy, angiogenesis stimulation
title Modern methods of stimulation of angiogenesis in patients with critical limb ischemia (review)
title_full Modern methods of stimulation of angiogenesis in patients with critical limb ischemia (review)
title_fullStr Modern methods of stimulation of angiogenesis in patients with critical limb ischemia (review)
title_full_unstemmed Modern methods of stimulation of angiogenesis in patients with critical limb ischemia (review)
title_short Modern methods of stimulation of angiogenesis in patients with critical limb ischemia (review)
title_sort modern methods of stimulation of angiogenesis in patients with critical limb ischemia review
topic critical limb ischemia, cell therapy, gene therapy, angiogenesis stimulation
url http://www.ojs.ukw.edu.pl/index.php/johs/article/view/4464
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