Oncostatin M Receptor Type II Knockout Mitigates Inflammation and Improves Survival from Sepsis in Mice
Sepsis remains one of the leading causes of death worldwide. Oncostatin M (OSM), an interleukin (IL)-6 family cytokine, can be found at high levels in septic patients. However, little is known about its role in sepsis. This study aimed to determine if the genetic knockout of OSM receptor (OSMR) type...
Main Authors: | Saad Y. Salim, Nour AlMalki, Kimberly F. Macala, Alyssa Wiedemeyer, Thomas F. Mueller, Thomas A. Churchill, Stephane L. Bourque, Rachel G. Khadaroo |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2023-02-01
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Series: | Biomedicines |
Subjects: | |
Online Access: | https://www.mdpi.com/2227-9059/11/2/483 |
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