Effects of verapamil combinations with enalapril or indapamide on plasma, vascular and platelet hemostasis and biochemical markers of endothelial dysfunction in patients with arterial hypertension and metabolic syndrome

The combination of verapamil retard and enalapril, or verapamil retard and indapamide SR similarly and significantly increased high-density lipoprotein cholesterol and stable NO2 metabolite levels, reducing platelet aggregation in patients with metabolic syndrome (MS). Compared to the combination of...

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Main Authors: N. M. Krasnova, T. P. Kalashnikova, A. I. Vengerovsky, E. M. Idrisova, I. V. Kulagina, T. E. Suslova, O. V. Gruzdeva, S. V. Kremeno, N. M. Zheltonogova, A. A. Shishkina, R. S. Karpov
Format: Article
Language:Russian
Published: «FIRMA «SILICEA» LLC 2008-06-01
Series:Российский кардиологический журнал
Subjects:
Online Access:https://russjcardiol.elpub.ru/jour/article/view/1572
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author N. M. Krasnova
T. P. Kalashnikova
A. I. Vengerovsky
E. M. Idrisova
I. V. Kulagina
T. E. Suslova
O. V. Gruzdeva
S. V. Kremeno
N. M. Zheltonogova
A. A. Shishkina
R. S. Karpov
author_facet N. M. Krasnova
T. P. Kalashnikova
A. I. Vengerovsky
E. M. Idrisova
I. V. Kulagina
T. E. Suslova
O. V. Gruzdeva
S. V. Kremeno
N. M. Zheltonogova
A. A. Shishkina
R. S. Karpov
author_sort N. M. Krasnova
collection DOAJ
description The combination of verapamil retard and enalapril, or verapamil retard and indapamide SR similarly and significantly increased high-density lipoprotein cholesterol and stable NO2 metabolite levels, reducing platelet aggregation in patients with metabolic syndrome (MS). Compared to the combination of verapamil retard and indapamide SR, the combination of verapamil retard and enalapril significantly reduced atherogenicity coefficient, glycated hemoglobin, glucose and soluble fibrin-monomer complex levels, increasing nitrite concentration and activating plasminogen.
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spelling doaj.art-9e6fe648cdf64d249e81f9bdf98ebe162023-03-29T21:23:15Zrus«FIRMA «SILICEA» LLCРоссийский кардиологический журнал1560-40712618-76202008-06-010349541351Effects of verapamil combinations with enalapril or indapamide on plasma, vascular and platelet hemostasis and biochemical markers of endothelial dysfunction in patients with arterial hypertension and metabolic syndromeN. M. Krasnova0T. P. Kalashnikova1A. I. Vengerovsky2E. M. Idrisova3I. V. Kulagina4T. E. Suslova5O. V. Gruzdeva6S. V. Kremeno7N. M. Zheltonogova8A. A. Shishkina9R. S. Karpov10Сибирский государственный медицинский университет Федерального агентства по здравоохранению и социальному развитиюСибирский государственный медицинский университет Федерального агентства по здравоохранению и социальному развитиюСибирский государственный медицинский университет Федерального агентства по здравоохранению и социальному развитиюСибирский государственный медицинский университет Федерального агентства по здравоохранению и социальному развитиюНИИ кардиологии Томского научного центра Сибирского отделения РАМННИИ кардиологии Томского научного центра Сибирского отделения РАМННИИ кардиологии Томского научного центра Сибирского отделения РАМННИИ кардиологии Томского научного центра Сибирского отделения РАМННИИ кардиологии Томского научного центра Сибирского отделения РАМНСибирский государственный медицинский университет Федерального агентства по здравоохранению и социальному развитиюНИИ кардиологии Томского научного центра Сибирского отделения РАМНThe combination of verapamil retard and enalapril, or verapamil retard and indapamide SR similarly and significantly increased high-density lipoprotein cholesterol and stable NO2 metabolite levels, reducing platelet aggregation in patients with metabolic syndrome (MS). Compared to the combination of verapamil retard and indapamide SR, the combination of verapamil retard and enalapril significantly reduced atherogenicity coefficient, glycated hemoglobin, glucose and soluble fibrin-monomer complex levels, increasing nitrite concentration and activating plasminogen.https://russjcardiol.elpub.ru/jour/article/view/1572metabolic syndromearterial hypertensionplatelet aggregationwillebrand factorno2verapamilenalaprilindapamide
spellingShingle N. M. Krasnova
T. P. Kalashnikova
A. I. Vengerovsky
E. M. Idrisova
I. V. Kulagina
T. E. Suslova
O. V. Gruzdeva
S. V. Kremeno
N. M. Zheltonogova
A. A. Shishkina
R. S. Karpov
Effects of verapamil combinations with enalapril or indapamide on plasma, vascular and platelet hemostasis and biochemical markers of endothelial dysfunction in patients with arterial hypertension and metabolic syndrome
Российский кардиологический журнал
metabolic syndrome
arterial hypertension
platelet aggregation
willebrand factor
no2
verapamil
enalapril
indapamide
title Effects of verapamil combinations with enalapril or indapamide on plasma, vascular and platelet hemostasis and biochemical markers of endothelial dysfunction in patients with arterial hypertension and metabolic syndrome
title_full Effects of verapamil combinations with enalapril or indapamide on plasma, vascular and platelet hemostasis and biochemical markers of endothelial dysfunction in patients with arterial hypertension and metabolic syndrome
title_fullStr Effects of verapamil combinations with enalapril or indapamide on plasma, vascular and platelet hemostasis and biochemical markers of endothelial dysfunction in patients with arterial hypertension and metabolic syndrome
title_full_unstemmed Effects of verapamil combinations with enalapril or indapamide on plasma, vascular and platelet hemostasis and biochemical markers of endothelial dysfunction in patients with arterial hypertension and metabolic syndrome
title_short Effects of verapamil combinations with enalapril or indapamide on plasma, vascular and platelet hemostasis and biochemical markers of endothelial dysfunction in patients with arterial hypertension and metabolic syndrome
title_sort effects of verapamil combinations with enalapril or indapamide on plasma vascular and platelet hemostasis and biochemical markers of endothelial dysfunction in patients with arterial hypertension and metabolic syndrome
topic metabolic syndrome
arterial hypertension
platelet aggregation
willebrand factor
no2
verapamil
enalapril
indapamide
url https://russjcardiol.elpub.ru/jour/article/view/1572
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