Paneth Cell-Like Component in Prostate Cancer - Case Report
Prostate adenocarcinoma with Paneth cell-like neuroendocrine differentiation is a rare entity. Foci of scattered cells and small clusters are found in the majority of described cases, although cases with predominant Paneth cell-like features have also been recorded. These cells contain eosinophilic...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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Sestre Milosrdnice University hospital, Institute of Clinical Medical Research
2018-01-01
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| Series: | Acta Clinica Croatica |
| Subjects: | |
| Online Access: | https://hrcak.srce.hr/file/305419 |
| _version_ | 1827282810636861440 |
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| author | Bernardica Jurić Šoip Šoipi Monika Ulamec Božo Krušlin |
| author_facet | Bernardica Jurić Šoip Šoipi Monika Ulamec Božo Krušlin |
| author_sort | Bernardica Jurić |
| collection | DOAJ |
| description | Prostate adenocarcinoma with Paneth cell-like neuroendocrine differentiation is a rare entity. Foci of scattered cells and small clusters are found in the majority of described cases, although cases with predominant Paneth cell-like features have also been recorded. These cells contain eosinophilic cyto-plasmic inclusions and lack androgen receptors, and are consequently immune to hormone therapy. It is, therefore, important for pathologists to recognize them. According to literature, clinical outcome depends on the standard grading of the conventional prostate cancer component. We report a case of a 54 year-old patient with prostatic adenocarcinoma showing Paneth cell-like neuroendocrine differentiation. |
| first_indexed | 2024-04-24T09:24:53Z |
| format | Article |
| id | doaj.art-9e77cf3ca86e4a05bd5c3b5e776646b7 |
| institution | Directory Open Access Journal |
| issn | 0353-9466 1333-9451 |
| language | English |
| last_indexed | 2024-04-24T09:24:53Z |
| publishDate | 2018-01-01 |
| publisher | Sestre Milosrdnice University hospital, Institute of Clinical Medical Research |
| record_format | Article |
| series | Acta Clinica Croatica |
| spelling | doaj.art-9e77cf3ca86e4a05bd5c3b5e776646b72024-04-15T15:09:16ZengSestre Milosrdnice University hospital, Institute of Clinical Medical ResearchActa Clinica Croatica0353-94661333-94512018-01-0157.Supplement 1858810.20471/acc.2018.57.s1.13Paneth Cell-Like Component in Prostate Cancer - Case ReportBernardica Jurić0Šoip Šoipi1Monika Ulamec2Božo Krušlin3Ljudevit Jurak Department of Pathology and Cytology, Sestre milosrdnice University Hospital Center, Zagreb, CroatiaDepartment of Urology, Sestre milosrdnice University Hospital Center, Zagreb, CroatiaLjudevit Jurak Department of Pathology and Cytology, Sestre milosrdnice University Hospital Center, Zagreb, Croatia; Department of Pathology, School of Medicine, University of Zagreb, Zagreb, CroatiaLjudevit Jurak Department of Pathology and Cytology, Sestre milosrdnice University Hospital Center, Zagreb, Croatia; Department of Pathology, School of Medicine, University of Zagreb, Zagreb, CroatiaProstate adenocarcinoma with Paneth cell-like neuroendocrine differentiation is a rare entity. Foci of scattered cells and small clusters are found in the majority of described cases, although cases with predominant Paneth cell-like features have also been recorded. These cells contain eosinophilic cyto-plasmic inclusions and lack androgen receptors, and are consequently immune to hormone therapy. It is, therefore, important for pathologists to recognize them. According to literature, clinical outcome depends on the standard grading of the conventional prostate cancer component. We report a case of a 54 year-old patient with prostatic adenocarcinoma showing Paneth cell-like neuroendocrine differentiation.https://hrcak.srce.hr/file/305419ProstateAdenocarcinomaPaneth cells |
| spellingShingle | Bernardica Jurić Šoip Šoipi Monika Ulamec Božo Krušlin Paneth Cell-Like Component in Prostate Cancer - Case Report Acta Clinica Croatica Prostate Adenocarcinoma Paneth cells |
| title | Paneth Cell-Like Component in Prostate Cancer - Case Report |
| title_full | Paneth Cell-Like Component in Prostate Cancer - Case Report |
| title_fullStr | Paneth Cell-Like Component in Prostate Cancer - Case Report |
| title_full_unstemmed | Paneth Cell-Like Component in Prostate Cancer - Case Report |
| title_short | Paneth Cell-Like Component in Prostate Cancer - Case Report |
| title_sort | paneth cell like component in prostate cancer case report |
| topic | Prostate Adenocarcinoma Paneth cells |
| url | https://hrcak.srce.hr/file/305419 |
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