Learning health systems and evidence ecosystems: a perspective on the future of evidence-based medicine and evidence-based guideline development

Abstract Despite forming the cornerstone of modern clinical practice for decades, implementation of evidence-based medicine at scale remains a crucial challenge for health systems. As a result, there has been a growing need for conceptual models to better contextualise and pragmatize the use of evid...

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Main Authors: D. Rajit, A. Johnson, E. Callander, H. Teede, J. Enticott
Format: Article
Language:English
Published: BMC 2024-01-01
Series:Health Research Policy and Systems
Subjects:
Online Access:https://doi.org/10.1186/s12961-023-01095-2
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author D. Rajit
A. Johnson
E. Callander
H. Teede
J. Enticott
author_facet D. Rajit
A. Johnson
E. Callander
H. Teede
J. Enticott
author_sort D. Rajit
collection DOAJ
description Abstract Despite forming the cornerstone of modern clinical practice for decades, implementation of evidence-based medicine at scale remains a crucial challenge for health systems. As a result, there has been a growing need for conceptual models to better contextualise and pragmatize the use of evidence-based medicine, particularly in tandem with patient-centred care. In this commentary, we highlight the emergence of the learning health system as one such model and analyse its potential role in pragmatizing both evidence-based medicine and patient-centred care. We apply the learning health system lens to contextualise the key activity of evidence-based guideline development and implementation, and highlight how current inefficiencies and bottlenecks in the evidence synthesis phase of evidence-based guideline development threaten downstream adherence. Lastly, we introduce the evidence ecosystem as a complementary model to learning health systems, and propose how innovative developments from the evidence ecosystem may be integrated with learning health systems to better enable health impact at speed and scale.
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spelling doaj.art-9e79f92a649d4d10b6b682a6340bdd772024-01-07T12:55:00ZengBMCHealth Research Policy and Systems1478-45052024-01-012211610.1186/s12961-023-01095-2Learning health systems and evidence ecosystems: a perspective on the future of evidence-based medicine and evidence-based guideline developmentD. Rajit0A. Johnson1E. Callander2H. Teede3J. Enticott4Monash Centre for Health Research and Implementation, Faculty of Medicine, Nursing, and Health Sciences, Monash UniversityMonash Partners Academic Health Sciences CentreMonash Centre for Health Research and Implementation, Faculty of Medicine, Nursing, and Health Sciences, Monash UniversityMonash Centre for Health Research and Implementation, Faculty of Medicine, Nursing, and Health Sciences, Monash UniversityMonash Centre for Health Research and Implementation, Faculty of Medicine, Nursing, and Health Sciences, Monash UniversityAbstract Despite forming the cornerstone of modern clinical practice for decades, implementation of evidence-based medicine at scale remains a crucial challenge for health systems. As a result, there has been a growing need for conceptual models to better contextualise and pragmatize the use of evidence-based medicine, particularly in tandem with patient-centred care. In this commentary, we highlight the emergence of the learning health system as one such model and analyse its potential role in pragmatizing both evidence-based medicine and patient-centred care. We apply the learning health system lens to contextualise the key activity of evidence-based guideline development and implementation, and highlight how current inefficiencies and bottlenecks in the evidence synthesis phase of evidence-based guideline development threaten downstream adherence. Lastly, we introduce the evidence ecosystem as a complementary model to learning health systems, and propose how innovative developments from the evidence ecosystem may be integrated with learning health systems to better enable health impact at speed and scale.https://doi.org/10.1186/s12961-023-01095-2Learning health systemsEvidence ecosystemsEvidence-based medicinePerson-centred careEvidence-based guidelines
spellingShingle D. Rajit
A. Johnson
E. Callander
H. Teede
J. Enticott
Learning health systems and evidence ecosystems: a perspective on the future of evidence-based medicine and evidence-based guideline development
Health Research Policy and Systems
Learning health systems
Evidence ecosystems
Evidence-based medicine
Person-centred care
Evidence-based guidelines
title Learning health systems and evidence ecosystems: a perspective on the future of evidence-based medicine and evidence-based guideline development
title_full Learning health systems and evidence ecosystems: a perspective on the future of evidence-based medicine and evidence-based guideline development
title_fullStr Learning health systems and evidence ecosystems: a perspective on the future of evidence-based medicine and evidence-based guideline development
title_full_unstemmed Learning health systems and evidence ecosystems: a perspective on the future of evidence-based medicine and evidence-based guideline development
title_short Learning health systems and evidence ecosystems: a perspective on the future of evidence-based medicine and evidence-based guideline development
title_sort learning health systems and evidence ecosystems a perspective on the future of evidence based medicine and evidence based guideline development
topic Learning health systems
Evidence ecosystems
Evidence-based medicine
Person-centred care
Evidence-based guidelines
url https://doi.org/10.1186/s12961-023-01095-2
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