4-Phenylbutyric Acid Increases GLUT4 Gene Expression through Suppression of HDAC5 but not Endoplasmic Reticulum Stress
Background: The chemical chaperone 4-phenylbutyric acid (4-PBA) has been shown to relieve endoplasmic reticulum (ER) stress. Therefore, it improves insulin sensitivity and promotes glucose metabolism in skeletal muscle. Glucose transporter type 4 (GLUT4), as a major glucose transporter protein, play...
Main Authors: | Hailong Hu, Li Li, Changlin Wang, Hongjuan He, Ke Mao, Xiao Ma, Ruoyu Shi, Yuri Oh, FengWei Zhang, Ying Lu, Qiong Wu, Ning Gu |
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格式: | 文件 |
语言: | English |
出版: |
Cell Physiol Biochem Press GmbH & Co KG
2014-06-01
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丛编: | Cellular Physiology and Biochemistry |
主题: | |
在线阅读: | http://www.karger.com/Article/FullText/362967 |
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