SERUM ALKALINE PHOSPHATASE LEVEL IN TYPE - 2 DIABETES MELLITUS AND ITS RELATION WITH PERIODONTITIS
Objective: This article may be cited as: Shaheen A, Khattak S, Khattak AM, Kamal A, Jaffari SA, Sher A. Serum alkaline phosphatase level in patients with type 2 diabetes mellitus and its relation with periodontitis. KUST Med J 2009; 1(2): 51-54.To study the level of serum alkaline phosphatase in d...
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| Format: | Article |
| Language: | English |
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Khyber Medical University
2010-01-01
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| Series: | Khyber Medical University Journal |
| Online Access: | https://www.kmuj.kmu.edu.pk/article/view/4821 |
| _version_ | 1811294201911967744 |
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| author | asmat shaheen Salim Khattak Aziz Marjan Khattak Asghar Kamal S A Jaffari Alam Sher |
| author_facet | asmat shaheen Salim Khattak Aziz Marjan Khattak Asghar Kamal S A Jaffari Alam Sher |
| author_sort | asmat shaheen |
| collection | DOAJ |
| description | Objective:
This article may be cited as:
Shaheen A, Khattak S, Khattak AM, Kamal A, Jaffari SA, Sher A. Serum alkaline phosphatase level in patients with type 2 diabetes mellitus and its relation with periodontitis. KUST Med J 2009; 1(2): 51-54.To study the level of serum alkaline phosphatase in diabetic patients with periodantitis and compare to control group. Material and Methods: This study was carried out in Pathology Department Gomal Medical College Dera Ismail Khan, from Jan. 2006 to June 2007. Subjects of type-2 diabetes mellitus having periodontitis (group A), diabetics without periodontitis (group B), non-diabetics with periodontitis (group C) and control subjects (non-diabetics and without periodontitis) were included. Patients of both sexes aged between 31 and 70 years were studied. Blood samples were analysed for fasting, post-prandial sugar and serum alkaline phosphatase levels. Depth of periodontal pocket >3mm was labeled as a patient suffering from periodontitis. A WHO recommended probe gently placed to the base of the pocket and the depth of insertion was read. At least six points on each tooth; mesio-buccal, mid-buccal and distobuccal and the corresponding lingual sites were measured. Patients with other diagnosed diseases affecting ALP levels were excluded. Results: No significant difference in fasting and post prandial blood sugar level in control and the non-diabetics with periodotitis. ALP showed significant rise in both diabetics and non-diabetics with periodantitis. ALP is raised slightly in diabetics without periodantitis but significantly with periodantitis (groups A & C), however, depth of pockets was very significantly more in patients with peridontitis compared to control and diabetics without periodontitis (group B). Conclusion: Periodontitis is a debilitating disease leading to significant rise in level of ALP in subjects with type 2 diabetes mellitus as well as in non-diabetics. Key words: Periodontitis, Type 2 Diabetes Mellitus, Alkaline Phosphatase. |
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| id | doaj.art-9e81ca2812b34f89a7e7091ed597fbe9 |
| institution | Directory Open Access Journal |
| issn | 2305-2643 2305-2651 |
| language | English |
| last_indexed | 2024-04-13T05:13:53Z |
| publishDate | 2010-01-01 |
| publisher | Khyber Medical University |
| record_format | Article |
| series | Khyber Medical University Journal |
| spelling | doaj.art-9e81ca2812b34f89a7e7091ed597fbe92022-12-22T03:00:57ZengKhyber Medical UniversityKhyber Medical University Journal2305-26432305-26512010-01-011251544821SERUM ALKALINE PHOSPHATASE LEVEL IN TYPE - 2 DIABETES MELLITUS AND ITS RELATION WITH PERIODONTITISasmat shaheenSalim KhattakAziz Marjan KhattakAsghar KamalS A JaffariAlam SherObjective: This article may be cited as: Shaheen A, Khattak S, Khattak AM, Kamal A, Jaffari SA, Sher A. Serum alkaline phosphatase level in patients with type 2 diabetes mellitus and its relation with periodontitis. KUST Med J 2009; 1(2): 51-54.To study the level of serum alkaline phosphatase in diabetic patients with periodantitis and compare to control group. Material and Methods: This study was carried out in Pathology Department Gomal Medical College Dera Ismail Khan, from Jan. 2006 to June 2007. Subjects of type-2 diabetes mellitus having periodontitis (group A), diabetics without periodontitis (group B), non-diabetics with periodontitis (group C) and control subjects (non-diabetics and without periodontitis) were included. Patients of both sexes aged between 31 and 70 years were studied. Blood samples were analysed for fasting, post-prandial sugar and serum alkaline phosphatase levels. Depth of periodontal pocket >3mm was labeled as a patient suffering from periodontitis. A WHO recommended probe gently placed to the base of the pocket and the depth of insertion was read. At least six points on each tooth; mesio-buccal, mid-buccal and distobuccal and the corresponding lingual sites were measured. Patients with other diagnosed diseases affecting ALP levels were excluded. Results: No significant difference in fasting and post prandial blood sugar level in control and the non-diabetics with periodotitis. ALP showed significant rise in both diabetics and non-diabetics with periodantitis. ALP is raised slightly in diabetics without periodantitis but significantly with periodantitis (groups A & C), however, depth of pockets was very significantly more in patients with peridontitis compared to control and diabetics without periodontitis (group B). Conclusion: Periodontitis is a debilitating disease leading to significant rise in level of ALP in subjects with type 2 diabetes mellitus as well as in non-diabetics. Key words: Periodontitis, Type 2 Diabetes Mellitus, Alkaline Phosphatase.https://www.kmuj.kmu.edu.pk/article/view/4821 |
| spellingShingle | asmat shaheen Salim Khattak Aziz Marjan Khattak Asghar Kamal S A Jaffari Alam Sher SERUM ALKALINE PHOSPHATASE LEVEL IN TYPE - 2 DIABETES MELLITUS AND ITS RELATION WITH PERIODONTITIS Khyber Medical University Journal |
| title | SERUM ALKALINE PHOSPHATASE LEVEL IN TYPE - 2 DIABETES MELLITUS AND ITS RELATION WITH PERIODONTITIS |
| title_full | SERUM ALKALINE PHOSPHATASE LEVEL IN TYPE - 2 DIABETES MELLITUS AND ITS RELATION WITH PERIODONTITIS |
| title_fullStr | SERUM ALKALINE PHOSPHATASE LEVEL IN TYPE - 2 DIABETES MELLITUS AND ITS RELATION WITH PERIODONTITIS |
| title_full_unstemmed | SERUM ALKALINE PHOSPHATASE LEVEL IN TYPE - 2 DIABETES MELLITUS AND ITS RELATION WITH PERIODONTITIS |
| title_short | SERUM ALKALINE PHOSPHATASE LEVEL IN TYPE - 2 DIABETES MELLITUS AND ITS RELATION WITH PERIODONTITIS |
| title_sort | serum alkaline phosphatase level in type 2 diabetes mellitus and its relation with periodontitis |
| url | https://www.kmuj.kmu.edu.pk/article/view/4821 |
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