TREATMENT OF CLOSTRIDIUM DIFFICILE- ASSOCIATED DISEASE
Clostridium difficile is a Gram-positive, spore-forming, anaerobic bacillus that is widely distributed in the environment, but is found as a part of a normal large bowel flora in approximately 3% of normal adults. C. difficile produces two protein exotoxins: toxin A and toxin B. Both toxins are resp...
| Main Authors: | , , , , , , , |
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| Format: | Article |
| Language: | English |
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University in Nis, Faculty of Medicine
2007-04-01
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| Series: | Acta Medica Medianae |
| Subjects: | |
| Online Access: | http://publisher.medfak.ni.ac.rs/2007-html/2-broj/TREATMENT%20OF%20CLOSTRIDIUM%20DIFFICILE....pdf |
| _version_ | 1818148754948096000 |
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| author | Snezana Antic-Mladenovic Biljana Miljkovic-Selimovic Dobrila Stankovic-Djordjevic Gordana Randjelovic Branislava Kocic Predrag Stojanovic Kristina Stojanovic Tatjana Babic |
| author_facet | Snezana Antic-Mladenovic Biljana Miljkovic-Selimovic Dobrila Stankovic-Djordjevic Gordana Randjelovic Branislava Kocic Predrag Stojanovic Kristina Stojanovic Tatjana Babic |
| author_sort | Snezana Antic-Mladenovic |
| collection | DOAJ |
| description | Clostridium difficile is a Gram-positive, spore-forming, anaerobic bacillus that is widely distributed in the environment, but is found as a part of a normal large bowel flora in approximately 3% of normal adults. C. difficile produces two protein exotoxins: toxin A and toxin B. Both toxins are responsible for causing the sings and symptoms of disease.C. difficile is now thought to be responsible for a spectrum of diseases, ranging from asymptomatic colonization to diarrhea of varying severity, life-threatening colitis, often as a consequence of long-term antibiotic exposure. This spectrum has become known as C. difficile-associated disease (CDAD).Treatment of Clostridium difficile-associated disease demand administration of effi-cient antibiotics (vancomycin, metronidazole), anion exchange resins and probiotics (Lactobacillus spp., Saccharomyces boulardii). |
| first_indexed | 2024-12-11T12:56:10Z |
| format | Article |
| id | doaj.art-9e8416df8801436aa5ef6d88e77b85f8 |
| institution | Directory Open Access Journal |
| issn | 0365-4478 |
| language | English |
| last_indexed | 2024-12-11T12:56:10Z |
| publishDate | 2007-04-01 |
| publisher | University in Nis, Faculty of Medicine |
| record_format | Article |
| series | Acta Medica Medianae |
| spelling | doaj.art-9e8416df8801436aa5ef6d88e77b85f82022-12-22T01:06:35ZengUniversity in Nis, Faculty of MedicineActa Medica Medianae0365-44782007-04-014623134TREATMENT OF CLOSTRIDIUM DIFFICILE- ASSOCIATED DISEASESnezana Antic-MladenovicBiljana Miljkovic-SelimovicDobrila Stankovic-DjordjevicGordana RandjelovicBranislava KocicPredrag StojanovicKristina StojanovicTatjana BabicClostridium difficile is a Gram-positive, spore-forming, anaerobic bacillus that is widely distributed in the environment, but is found as a part of a normal large bowel flora in approximately 3% of normal adults. C. difficile produces two protein exotoxins: toxin A and toxin B. Both toxins are responsible for causing the sings and symptoms of disease.C. difficile is now thought to be responsible for a spectrum of diseases, ranging from asymptomatic colonization to diarrhea of varying severity, life-threatening colitis, often as a consequence of long-term antibiotic exposure. This spectrum has become known as C. difficile-associated disease (CDAD).Treatment of Clostridium difficile-associated disease demand administration of effi-cient antibiotics (vancomycin, metronidazole), anion exchange resins and probiotics (Lactobacillus spp., Saccharomyces boulardii).http://publisher.medfak.ni.ac.rs/2007-html/2-broj/TREATMENT%20OF%20CLOSTRIDIUM%20DIFFICILE....pdfClostridium difficileCDADtreatment |
| spellingShingle | Snezana Antic-Mladenovic Biljana Miljkovic-Selimovic Dobrila Stankovic-Djordjevic Gordana Randjelovic Branislava Kocic Predrag Stojanovic Kristina Stojanovic Tatjana Babic TREATMENT OF CLOSTRIDIUM DIFFICILE- ASSOCIATED DISEASE Acta Medica Medianae Clostridium difficile CDAD treatment |
| title | TREATMENT OF CLOSTRIDIUM DIFFICILE- ASSOCIATED DISEASE |
| title_full | TREATMENT OF CLOSTRIDIUM DIFFICILE- ASSOCIATED DISEASE |
| title_fullStr | TREATMENT OF CLOSTRIDIUM DIFFICILE- ASSOCIATED DISEASE |
| title_full_unstemmed | TREATMENT OF CLOSTRIDIUM DIFFICILE- ASSOCIATED DISEASE |
| title_short | TREATMENT OF CLOSTRIDIUM DIFFICILE- ASSOCIATED DISEASE |
| title_sort | treatment of clostridium difficile associated disease |
| topic | Clostridium difficile CDAD treatment |
| url | http://publisher.medfak.ni.ac.rs/2007-html/2-broj/TREATMENT%20OF%20CLOSTRIDIUM%20DIFFICILE....pdf |
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