LncRNA H19 Suppresses Osteosarcomagenesis by Regulating snoRNAs and DNA Repair Protein Complexes

LncRNA H19 Suppresses Osteosarcomagenesis by Regulating snoRNAs and DNA Repair Protein Complexes

Osteosarcoma is one of the most frequent common primary malignant tumors in childhood and adolescence. Long non-coding RNAs (lncRNAs) have been reported to regulate the initiation and progression of tumors. However, the exact molecular mechanisms involving lncRNA in osteosarcomagenesis remain largel...

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Bibliographic Details
Main Authors: An Xu, Mo-Fan Huang, Dandan Zhu, Julian A. Gingold, Danielle A. Bazer, Betty Chang, Donghui Wang, Chien-Chen Lai, Ihor R. Lemischka, Ruiying Zhao, Dung-Fang Lee
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-01-01
Series:Frontiers in Genetics
Subjects:
osteosarcoma
H19 lncRNA
iPSCs
Li-Fraumeni syndrome
snoRNA
p53
Online Access:https://www.frontiersin.org/articles/10.3389/fgene.2020.611823/full

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