Loosening Neuro-Optic Structures Dosimetric Constraints Provides High 5-Year Local Recurrence-Free Survival With Acceptable Toxicity in T4 Nasopharyngeal Carcinoma Patients Treated With Intensity-Modulated Radiotherapy

Loosening Neuro-Optic Structures Dosimetric Constraints Provides High 5-Year Local Recurrence-Free Survival With Acceptable Toxicity in T4 Nasopharyngeal Carcinoma Patients Treated With Intensity-Modulated Radiotherapy

ObjectiveWhether the original dosimetric constraints of neuro-optic structures (NOS) are appropriate for patients with nasopharyngeal carcinoma (NPC) undergoing intensity-modulated radiotherapy (IMRT) remains controversial. The present study compared the survival rates and radiation-induced optic ne...

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Bibliographic Details
Main Authors: Tingting Zhang, Meng Xu, Jinglin Mi, Hui Yang, Zhengchun Liu, Lulu Huang, Kai Hu, Rensheng Wang
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-02-01
Series:Frontiers in Oncology
Subjects:
neuro-optic structures
dosimetric constraints
radiation-induced optic neuropathy
nasopharyngeal carcinoma
intensity-modulated radiotherapy
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2021.598320/full

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