Predictors of Length of Stay, Mortality and Rehospitalization in COPD Patients: A Retrospective Cohort Study
Chronic obstructive pulmonary disease (COPD) is a highly prevalent chronic lung disease that has a significant impact on individuals and healthcare systems worldwide. This study aimed to identify factors that predict the length of a hospital stay (LOHS), one-year mortality, and rehospitalization wit...
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| Format: | Article |
| Language: | English |
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MDPI AG
2023-08-01
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| Series: | Journal of Clinical Medicine |
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| Online Access: | https://www.mdpi.com/2077-0383/12/16/5322 |
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| author | Giorgia Lüthi-Corridori Maria Boesing Nicola Ottensarendt Anne Barbara Leuppi-Taegtmeyer Philipp Schuetz Joerg Daniel Leuppi |
| author_facet | Giorgia Lüthi-Corridori Maria Boesing Nicola Ottensarendt Anne Barbara Leuppi-Taegtmeyer Philipp Schuetz Joerg Daniel Leuppi |
| author_sort | Giorgia Lüthi-Corridori |
| collection | DOAJ |
| description | Chronic obstructive pulmonary disease (COPD) is a highly prevalent chronic lung disease that has a significant impact on individuals and healthcare systems worldwide. This study aimed to identify factors that predict the length of a hospital stay (LOHS), one-year mortality, and rehospitalization within 6 months in patients admitted for acute exacerbation of COPD (AECOPD). A retrospective cohort study was conducted using data from 170 patients admitted to a district general hospital in Switzerland between January 2019 and February 2020. Sociodemographic and health-related variables measured at admission were analyzed as potential predictors. Multivariable zero-truncated negative binomial and logistic regression analyses were performed to assess the risk factors for LOHS (primary endpoint), mortality, and rehospitalization. The results show that an indication for oxygen supplementation was the only significant predictor of LOHS. In the logistic regression analysis, older age, COPD severity stages GOLD III and IV, active cancer and arrhythmias were associated with higher mortality, whereas rehabilitation after discharge was associated with lower mortality. There were no significant associations regarding rehospitalization. This study identified routinely available predictors for LOHS and mortality, which may further advance our understanding of AECOPD and thereby improve patient management, discharge planning, and hospital costs. The protective effect of rehabilitation after hospitalization regarding lower mortality warrants further confirmation and may improve the comprehensive management of patients with AECOPD. |
| first_indexed | 2024-03-10T23:50:42Z |
| format | Article |
| id | doaj.art-9e89916507224b9f902aabe29c01e0d8 |
| institution | Directory Open Access Journal |
| issn | 2077-0383 |
| language | English |
| last_indexed | 2024-03-10T23:50:42Z |
| publishDate | 2023-08-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Journal of Clinical Medicine |
| spelling | doaj.art-9e89916507224b9f902aabe29c01e0d82023-11-19T01:41:31ZengMDPI AGJournal of Clinical Medicine2077-03832023-08-011216532210.3390/jcm12165322Predictors of Length of Stay, Mortality and Rehospitalization in COPD Patients: A Retrospective Cohort StudyGiorgia Lüthi-Corridori0Maria Boesing1Nicola Ottensarendt2Anne Barbara Leuppi-Taegtmeyer3Philipp Schuetz4Joerg Daniel Leuppi5University Center of Internal Medicine, Cantonal Hospital Baselland, 4410 Liestal, SwitzerlandUniversity Center of Internal Medicine, Cantonal Hospital Baselland, 4410 Liestal, SwitzerlandUniversity Center of Internal Medicine, Cantonal Hospital Baselland, 4410 Liestal, SwitzerlandUniversity Center of Internal Medicine, Cantonal Hospital Baselland, 4410 Liestal, SwitzerlandFaculty of Medicine, University of Basel, 4056 Basel, SwitzerlandUniversity Center of Internal Medicine, Cantonal Hospital Baselland, 4410 Liestal, SwitzerlandChronic obstructive pulmonary disease (COPD) is a highly prevalent chronic lung disease that has a significant impact on individuals and healthcare systems worldwide. This study aimed to identify factors that predict the length of a hospital stay (LOHS), one-year mortality, and rehospitalization within 6 months in patients admitted for acute exacerbation of COPD (AECOPD). A retrospective cohort study was conducted using data from 170 patients admitted to a district general hospital in Switzerland between January 2019 and February 2020. Sociodemographic and health-related variables measured at admission were analyzed as potential predictors. Multivariable zero-truncated negative binomial and logistic regression analyses were performed to assess the risk factors for LOHS (primary endpoint), mortality, and rehospitalization. The results show that an indication for oxygen supplementation was the only significant predictor of LOHS. In the logistic regression analysis, older age, COPD severity stages GOLD III and IV, active cancer and arrhythmias were associated with higher mortality, whereas rehabilitation after discharge was associated with lower mortality. There were no significant associations regarding rehospitalization. This study identified routinely available predictors for LOHS and mortality, which may further advance our understanding of AECOPD and thereby improve patient management, discharge planning, and hospital costs. The protective effect of rehabilitation after hospitalization regarding lower mortality warrants further confirmation and may improve the comprehensive management of patients with AECOPD.https://www.mdpi.com/2077-0383/12/16/5322AECOPDLOHSrehospitalizationmortality |
| spellingShingle | Giorgia Lüthi-Corridori Maria Boesing Nicola Ottensarendt Anne Barbara Leuppi-Taegtmeyer Philipp Schuetz Joerg Daniel Leuppi Predictors of Length of Stay, Mortality and Rehospitalization in COPD Patients: A Retrospective Cohort Study Journal of Clinical Medicine AECOPD LOHS rehospitalization mortality |
| title | Predictors of Length of Stay, Mortality and Rehospitalization in COPD Patients: A Retrospective Cohort Study |
| title_full | Predictors of Length of Stay, Mortality and Rehospitalization in COPD Patients: A Retrospective Cohort Study |
| title_fullStr | Predictors of Length of Stay, Mortality and Rehospitalization in COPD Patients: A Retrospective Cohort Study |
| title_full_unstemmed | Predictors of Length of Stay, Mortality and Rehospitalization in COPD Patients: A Retrospective Cohort Study |
| title_short | Predictors of Length of Stay, Mortality and Rehospitalization in COPD Patients: A Retrospective Cohort Study |
| title_sort | predictors of length of stay mortality and rehospitalization in copd patients a retrospective cohort study |
| topic | AECOPD LOHS rehospitalization mortality |
| url | https://www.mdpi.com/2077-0383/12/16/5322 |
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