A Case Presentation of Gastrointestinal Stromal Tumor of Duodenum
A gastrointestinal stromal tumor (GIST) is the most common mesenchymal tumor of the gastrointestinal tract. It is caused by the mutation in KIT and PDGFRα genes. It constitutes <1% of all gastrointestinal tumors. Duodenal GISTs constitute 4.5% of all GISTs. We report a 61-year-old lady, presented...
| Main Authors: | , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Codon Publications
2021-06-01
|
| Series: | Journal of Renal and Hepatic Disorders |
| Subjects: | |
| Online Access: | http://jrenhep.com/index.php/jrenhep/article/view/112 |
| _version_ | 1818405281871167488 |
|---|---|
| author | Aamir Ghazanfar Afifa Asghar Farrukh Zaman Hassan Mumtaz Shahzeb Habib Shahzaib Ahmad |
| author_facet | Aamir Ghazanfar Afifa Asghar Farrukh Zaman Hassan Mumtaz Shahzeb Habib Shahzaib Ahmad |
| author_sort | Aamir Ghazanfar |
| collection | DOAJ |
| description | A gastrointestinal stromal tumor (GIST) is the most common mesenchymal tumor of the gastrointestinal tract. It is caused by the mutation in KIT and PDGFRα genes. It constitutes <1% of all gastrointestinal tumors. Duodenal GISTs constitute 4.5% of all GISTs. We report a 61-year-old lady, presented with generalized abdominal pain, vomiting, abdominal distension, and nausea for the last 3 years. Physical exam-ination showed a pallor and on abdominal examination, a large palpable mass was extending from the pelvis to the right upper quadrant of the abdomen. The CT scan showed a large heterogeneously echogenic mass in the abdomen and pelvis with no lymphadenopathy and distant metastasis in this region. Laparotomy showed a large globular mass extending from the pelvis to the right upper quadrant of the abdomen adherent to the wall of a third part of the duodenum. Complete surgical resection of tumor done with an intact capsule. Microscopic examination showed neoplastic spindle cells with tumor necrosis. An immunohistochemical study confirmed GIST. |
| first_indexed | 2024-12-14T08:53:34Z |
| format | Article |
| id | doaj.art-9e8a4ab2058b44e48ceb43c85100be97 |
| institution | Directory Open Access Journal |
| issn | 2207-3744 |
| language | English |
| last_indexed | 2024-12-14T08:53:34Z |
| publishDate | 2021-06-01 |
| publisher | Codon Publications |
| record_format | Article |
| series | Journal of Renal and Hepatic Disorders |
| spelling | doaj.art-9e8a4ab2058b44e48ceb43c85100be972022-12-21T23:09:00ZengCodon PublicationsJournal of Renal and Hepatic Disorders2207-37442021-06-015110.15586/jrenhep.v5i1.112A Case Presentation of Gastrointestinal Stromal Tumor of DuodenumAamir Ghazanfar0Afifa Asghar1Farrukh Zaman2Hassan Mumtaz3Shahzeb Habib4Shahzaib Ahmad 5KRL Hospital IslamabadKRL Hospital IslamabadKRL Hospital IslamabadKRL Hospital, Islamabad, PakistanKRL Hospital Islamabad PakistanKing Edward Medical University LahoreA gastrointestinal stromal tumor (GIST) is the most common mesenchymal tumor of the gastrointestinal tract. It is caused by the mutation in KIT and PDGFRα genes. It constitutes <1% of all gastrointestinal tumors. Duodenal GISTs constitute 4.5% of all GISTs. We report a 61-year-old lady, presented with generalized abdominal pain, vomiting, abdominal distension, and nausea for the last 3 years. Physical exam-ination showed a pallor and on abdominal examination, a large palpable mass was extending from the pelvis to the right upper quadrant of the abdomen. The CT scan showed a large heterogeneously echogenic mass in the abdomen and pelvis with no lymphadenopathy and distant metastasis in this region. Laparotomy showed a large globular mass extending from the pelvis to the right upper quadrant of the abdomen adherent to the wall of a third part of the duodenum. Complete surgical resection of tumor done with an intact capsule. Microscopic examination showed neoplastic spindle cells with tumor necrosis. An immunohistochemical study confirmed GIST.http://jrenhep.com/index.php/jrenhep/article/view/112cancer interventionduodenumtumor surgery |
| spellingShingle | Aamir Ghazanfar Afifa Asghar Farrukh Zaman Hassan Mumtaz Shahzeb Habib Shahzaib Ahmad A Case Presentation of Gastrointestinal Stromal Tumor of Duodenum Journal of Renal and Hepatic Disorders cancer intervention duodenum tumor surgery |
| title | A Case Presentation of Gastrointestinal Stromal Tumor of Duodenum |
| title_full | A Case Presentation of Gastrointestinal Stromal Tumor of Duodenum |
| title_fullStr | A Case Presentation of Gastrointestinal Stromal Tumor of Duodenum |
| title_full_unstemmed | A Case Presentation of Gastrointestinal Stromal Tumor of Duodenum |
| title_short | A Case Presentation of Gastrointestinal Stromal Tumor of Duodenum |
| title_sort | case presentation of gastrointestinal stromal tumor of duodenum |
| topic | cancer intervention duodenum tumor surgery |
| url | http://jrenhep.com/index.php/jrenhep/article/view/112 |
| work_keys_str_mv | AT aamirghazanfar acasepresentationofgastrointestinalstromaltumorofduodenum AT afifaasghar acasepresentationofgastrointestinalstromaltumorofduodenum AT farrukhzaman acasepresentationofgastrointestinalstromaltumorofduodenum AT hassanmumtaz acasepresentationofgastrointestinalstromaltumorofduodenum AT shahzebhabib acasepresentationofgastrointestinalstromaltumorofduodenum AT shahzaibahmad acasepresentationofgastrointestinalstromaltumorofduodenum AT aamirghazanfar casepresentationofgastrointestinalstromaltumorofduodenum AT afifaasghar casepresentationofgastrointestinalstromaltumorofduodenum AT farrukhzaman casepresentationofgastrointestinalstromaltumorofduodenum AT hassanmumtaz casepresentationofgastrointestinalstromaltumorofduodenum AT shahzebhabib casepresentationofgastrointestinalstromaltumorofduodenum AT shahzaibahmad casepresentationofgastrointestinalstromaltumorofduodenum |