TCF12 Deficiency Impairs the Proliferation of Glioblastoma Tumor Cells and Improves Survival

TCF12 Deficiency Impairs the Proliferation of Glioblastoma Tumor Cells and Improves Survival

Isocitrate dehydrogenase (IDH)-wild-type glioblastoma (GBM) is the most common and aggressive primary brain tumor which carries a very poor overall prognosis and is universally fatal. Understanding the transcriptional regulation of the proliferation of GBM tumor cells is critical for developing nove...

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Bibliographic Details
Main Authors: Yunong Pang, Sichang Zhou, Paul Zumbo, Doron Betel, Babacar Cisse
Format: Article
Language:English
Published: MDPI AG 2023-03-01
Series:Cancers
Subjects:
glioblastomas (GBMs)
TCF12
cell cycle and proliferation
xenograft
oligodendrocytic lineage
Online Access:https://www.mdpi.com/2072-6694/15/7/2033

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