Suppressive IL-17A+Foxp3+ and ex-Th17 IL-17AnegFoxp3+ Treg cells are a source of tumour-associated Treg cells
Th17 cells can transdifferentiate into regulatory T (Treg) cells. Here the authors characterize tumour-driven Th17-to-Tregcell transdifferentiation and identify potential cancer therapy targets.
| Main Authors: | , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2017-03-01
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| Series: | Nature Communications |
| Online Access: | https://doi.org/10.1038/ncomms14649 |
| Summary: | Th17 cells can transdifferentiate into regulatory T (Treg) cells. Here the authors characterize tumour-driven Th17-to-Tregcell transdifferentiation and identify potential cancer therapy targets. |
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| ISSN: | 2041-1723 |