SARS-CoV-2 induces “cytokine storm” hyperinflammatory responses in RA patients through pyroptosis

SARS-CoV-2 induces “cytokine storm” hyperinflammatory responses in RA patients through pyroptosis

BackgroundThe coronavirus disease (COVID-19) is a pandemic disease that threatens worldwide public health, and rheumatoid arthritis (RA) is the most common autoimmune disease. COVID-19 and RA are each strong risk factors for the other, but their molecular mechanisms are unclear. This study aims to i...

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Bibliographic Details
Main Authors: Qingcong Zheng, Rongjie Lin, Yuchao Chen, Qi Lv, Jin Zhang, Jingbo Zhai, Weihong Xu, Wanming Wang
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-12-01
Series:Frontiers in Immunology
Subjects:
SARS-CoV-2
COVID-19
rheumatoid arthritis
pyroptosis
caspase-1
minocycline
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.1058884/full

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