Metabolic ketoacidosis with normal blood glucose: A rare complication of sodium–glucose cotransporter 2 inhibitors

Ketoacidosis is a significant and often a life-threatening complication of diabetes mellitus seen mostly in type 1 diabetes mellitus as well as occasionally in type 2 diabetes mellitus. Diabetic ketoacidosis usually manifests with high blood glucose more than 250 mg/dL, but euglycemic diabetic ketoa...

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Main Authors: Saad Ullah, Noman Khan, Hassan Zeb, Hassan Tahir
Format: Article
Language:English
Published: SAGE Publishing 2016-11-01
Series:SAGE Open Medical Case Reports
Online Access:https://doi.org/10.1177/2050313X16675259
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author Saad Ullah
Noman Khan
Hassan Zeb
Hassan Tahir
author_facet Saad Ullah
Noman Khan
Hassan Zeb
Hassan Tahir
author_sort Saad Ullah
collection DOAJ
description Ketoacidosis is a significant and often a life-threatening complication of diabetes mellitus seen mostly in type 1 diabetes mellitus as well as occasionally in type 2 diabetes mellitus. Diabetic ketoacidosis usually manifests with high blood glucose more than 250 mg/dL, but euglycemic diabetic ketoacidosis is defined as ketoacidosis associated with blood glucose level less than 250 mg/dL. Normal blood glucose in such patients results in significant delay in diagnosis and management of diabetic ketoacidosis, thus increasing mortality and morbidity. We present a case of euglycemic diabetic ketoacidosis secondary to canagliflozin in a type 2 diabetic patient.
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spelling doaj.art-9e916f2987d044199c37cb29fce183ef2022-12-21T23:41:37ZengSAGE PublishingSAGE Open Medical Case Reports2050-313X2016-11-01410.1177/2050313X1667525910.1177_2050313X16675259Metabolic ketoacidosis with normal blood glucose: A rare complication of sodium–glucose cotransporter 2 inhibitorsSaad UllahNoman KhanHassan ZebHassan TahirKetoacidosis is a significant and often a life-threatening complication of diabetes mellitus seen mostly in type 1 diabetes mellitus as well as occasionally in type 2 diabetes mellitus. Diabetic ketoacidosis usually manifests with high blood glucose more than 250 mg/dL, but euglycemic diabetic ketoacidosis is defined as ketoacidosis associated with blood glucose level less than 250 mg/dL. Normal blood glucose in such patients results in significant delay in diagnosis and management of diabetic ketoacidosis, thus increasing mortality and morbidity. We present a case of euglycemic diabetic ketoacidosis secondary to canagliflozin in a type 2 diabetic patient.https://doi.org/10.1177/2050313X16675259
spellingShingle Saad Ullah
Noman Khan
Hassan Zeb
Hassan Tahir
Metabolic ketoacidosis with normal blood glucose: A rare complication of sodium–glucose cotransporter 2 inhibitors
SAGE Open Medical Case Reports
title Metabolic ketoacidosis with normal blood glucose: A rare complication of sodium–glucose cotransporter 2 inhibitors
title_full Metabolic ketoacidosis with normal blood glucose: A rare complication of sodium–glucose cotransporter 2 inhibitors
title_fullStr Metabolic ketoacidosis with normal blood glucose: A rare complication of sodium–glucose cotransporter 2 inhibitors
title_full_unstemmed Metabolic ketoacidosis with normal blood glucose: A rare complication of sodium–glucose cotransporter 2 inhibitors
title_short Metabolic ketoacidosis with normal blood glucose: A rare complication of sodium–glucose cotransporter 2 inhibitors
title_sort metabolic ketoacidosis with normal blood glucose a rare complication of sodium glucose cotransporter 2 inhibitors
url https://doi.org/10.1177/2050313X16675259
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AT nomankhan metabolicketoacidosiswithnormalbloodglucoseararecomplicationofsodiumglucosecotransporter2inhibitors
AT hassanzeb metabolicketoacidosiswithnormalbloodglucoseararecomplicationofsodiumglucosecotransporter2inhibitors
AT hassantahir metabolicketoacidosiswithnormalbloodglucoseararecomplicationofsodiumglucosecotransporter2inhibitors