IgG4-Related disease with diffuse myopericardial involvement- value of CMR: a case report and literature review of cardiac involvement
Abstract Background IgG4-related disease is a fibro-inflammatory disorder with an unknown etiology, which can affect multiple organ systems, including the cardiovascular system. While most reported cases of cardiovascular involvement are primarily associated with the aorta, there have been sporadic...
| Main Authors: | , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
BMC
2024-04-01
|
| Series: | BMC Cardiovascular Disorders |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s12872-024-03874-3 |
| _version_ | 1797220015367258112 |
|---|---|
| author | Golnaz Houshmand Najme-Sadat Moosavi Amirhossein Shahbazkhani Hamidreza Pouraliakbar |
| author_facet | Golnaz Houshmand Najme-Sadat Moosavi Amirhossein Shahbazkhani Hamidreza Pouraliakbar |
| author_sort | Golnaz Houshmand |
| collection | DOAJ |
| description | Abstract Background IgG4-related disease is a fibro-inflammatory disorder with an unknown etiology, which can affect multiple organ systems, including the cardiovascular system. While most reported cases of cardiovascular involvement are primarily associated with the aorta, there have been sporadic reports of isolated cardiac involvement. Case presentation This paper presents a documented case of IgG4-related systemic disease with symptoms indicative of restrictive cardiomyopathy. Subsequent Cardiac Magnetic Resonance imaging revealed diffuse myopericardial involvement, characterized by pericardial thickening and enhancement, accompanied by subepicardial and myocardial infiltration. Considering the rarity of cardiac involvement in our case, we conducted a thorough review of the existing literature pertaining to various patterns of cardiac involvement in IgG4-related disease, as well as the diagnostic modalities that can be employed for accurate identification and assessment. Conclusions This case report sheds light on the importance of recognizing and evaluating cardiac manifestations in IgG4-related systemic disease to facilitate timely diagnosis and appropriate management. |
| first_indexed | 2024-04-24T12:42:49Z |
| format | Article |
| id | doaj.art-9e9a140cf589491c985a5846b46d630b |
| institution | Directory Open Access Journal |
| issn | 1471-2261 |
| language | English |
| last_indexed | 2024-04-24T12:42:49Z |
| publishDate | 2024-04-01 |
| publisher | BMC |
| record_format | Article |
| series | BMC Cardiovascular Disorders |
| spelling | doaj.art-9e9a140cf589491c985a5846b46d630b2024-04-07T11:07:44ZengBMCBMC Cardiovascular Disorders1471-22612024-04-012411810.1186/s12872-024-03874-3IgG4-Related disease with diffuse myopericardial involvement- value of CMR: a case report and literature review of cardiac involvementGolnaz Houshmand0Najme-Sadat Moosavi1Amirhossein Shahbazkhani2Hamidreza Pouraliakbar3Rajaie Cardiovascular Medical and Research Centre, Iran University of Medical SciencesTehran Heart Center, Tehran University of Medical SciencesDepartment of Radiology, Shariati Hospital, Tehran University of Medical SciencesRajaie Cardiovascular Medical and Research Centre, Iran University of Medical SciencesAbstract Background IgG4-related disease is a fibro-inflammatory disorder with an unknown etiology, which can affect multiple organ systems, including the cardiovascular system. While most reported cases of cardiovascular involvement are primarily associated with the aorta, there have been sporadic reports of isolated cardiac involvement. Case presentation This paper presents a documented case of IgG4-related systemic disease with symptoms indicative of restrictive cardiomyopathy. Subsequent Cardiac Magnetic Resonance imaging revealed diffuse myopericardial involvement, characterized by pericardial thickening and enhancement, accompanied by subepicardial and myocardial infiltration. Considering the rarity of cardiac involvement in our case, we conducted a thorough review of the existing literature pertaining to various patterns of cardiac involvement in IgG4-related disease, as well as the diagnostic modalities that can be employed for accurate identification and assessment. Conclusions This case report sheds light on the importance of recognizing and evaluating cardiac manifestations in IgG4-related systemic disease to facilitate timely diagnosis and appropriate management.https://doi.org/10.1186/s12872-024-03874-3IgG4-related diseaseCardiovascular systemRestrictive cardiomyopathyConstrictive pericarditis |
| spellingShingle | Golnaz Houshmand Najme-Sadat Moosavi Amirhossein Shahbazkhani Hamidreza Pouraliakbar IgG4-Related disease with diffuse myopericardial involvement- value of CMR: a case report and literature review of cardiac involvement BMC Cardiovascular Disorders IgG4-related disease Cardiovascular system Restrictive cardiomyopathy Constrictive pericarditis |
| title | IgG4-Related disease with diffuse myopericardial involvement- value of CMR: a case report and literature review of cardiac involvement |
| title_full | IgG4-Related disease with diffuse myopericardial involvement- value of CMR: a case report and literature review of cardiac involvement |
| title_fullStr | IgG4-Related disease with diffuse myopericardial involvement- value of CMR: a case report and literature review of cardiac involvement |
| title_full_unstemmed | IgG4-Related disease with diffuse myopericardial involvement- value of CMR: a case report and literature review of cardiac involvement |
| title_short | IgG4-Related disease with diffuse myopericardial involvement- value of CMR: a case report and literature review of cardiac involvement |
| title_sort | igg4 related disease with diffuse myopericardial involvement value of cmr a case report and literature review of cardiac involvement |
| topic | IgG4-related disease Cardiovascular system Restrictive cardiomyopathy Constrictive pericarditis |
| url | https://doi.org/10.1186/s12872-024-03874-3 |
| work_keys_str_mv | AT golnazhoushmand igg4relateddiseasewithdiffusemyopericardialinvolvementvalueofcmracasereportandliteraturereviewofcardiacinvolvement AT najmesadatmoosavi igg4relateddiseasewithdiffusemyopericardialinvolvementvalueofcmracasereportandliteraturereviewofcardiacinvolvement AT amirhosseinshahbazkhani igg4relateddiseasewithdiffusemyopericardialinvolvementvalueofcmracasereportandliteraturereviewofcardiacinvolvement AT hamidrezapouraliakbar igg4relateddiseasewithdiffusemyopericardialinvolvementvalueofcmracasereportandliteraturereviewofcardiacinvolvement |