Local treatment of a bone graft by soaking in zoledronic acid inhibits bone resorption and bone formation. A bone chamber study in rats

Local treatment of a bone graft by soaking in zoledronic acid inhibits bone resorption and bone formation. A bone chamber study in rats

<p>Abstract</p> <p>Background</p> <p>Bone grafts are frequently used in orthopaedic surgery. Graft remodelling is advantageous but can occur too quickly, and premature bone resorption might lead to decreased mechanical integrity of the graft. Bisphosphonates delay osteo...

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Bibliographic Details
Main Authors: Belfrage Ola, Isaksson Hanna, Tägil Magnus
Format: Article
Language:English
Published: BMC 2012-12-01
Series:BMC Musculoskeletal Disorders
Subjects:
Zoledronic acid
Bisphosphonates
Allograft
Local treatment
Bone remodelling
Online Access:http://www.biomedcentral.com/1471-2474/13/240

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