Poly(butylene succinate-<i>co</i>-ε-caprolactone) Copolyesters: Enzymatic Synthesis in Bulk and Thermal Properties
This work explores for the first time the enzymatic synthesis of poly(butylene-<i>co</i>-ε-caprolactone) (PBSCL) copolyesters in bulk using commercially available monomers (dimethyl succinate (DMS), 1,4-butanediol (BD), and ε-caprolactone (CL)). A preliminary kinetic study was carried ou...
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| Format: | Article |
| Language: | English |
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MDPI AG
2021-08-01
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| Series: | Polymers |
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| Online Access: | https://www.mdpi.com/2073-4360/13/16/2679 |
| _version_ | 1797522307086811136 |
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| author | María Núñez Sebastián Muñoz-Guerra Antxon Martínez de Ilarduya |
| author_facet | María Núñez Sebastián Muñoz-Guerra Antxon Martínez de Ilarduya |
| author_sort | María Núñez |
| collection | DOAJ |
| description | This work explores for the first time the enzymatic synthesis of poly(butylene-<i>co</i>-ε-caprolactone) (PBSCL) copolyesters in bulk using commercially available monomers (dimethyl succinate (DMS), 1,4-butanediol (BD), and ε-caprolactone (CL)). A preliminary kinetic study was carried out which demonstrated the higher reactivity of DMS over CL in the condensation/ring opening polymerization reaction, catalyzed by <i>Candida antarctica</i> lipase B. PBSCL copolyesters were obtained with high molecular weights and a random microstructure, as determined by <sup>13</sup>C NMR. They were thermally stable up to 300 °C, with thermal stability increasing with the content of CL in the copolyester. All of them were semicrystalline, with melting temperatures and enthalpies decreasing up to the eutectic point observed at intermediate compositions, and glass transition temperatures decreasing with the content of CL in the copolyester. The use of CALB provided copolyesters free from toxic metallic catalyst, which is very useful if the polymer is intended to be used for biomedical applications. |
| first_indexed | 2024-03-10T08:27:32Z |
| format | Article |
| id | doaj.art-9ea10fc5ac3a45f085c896dbd8ed405f |
| institution | Directory Open Access Journal |
| issn | 2073-4360 |
| language | English |
| last_indexed | 2024-03-10T08:27:32Z |
| publishDate | 2021-08-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Polymers |
| spelling | doaj.art-9ea10fc5ac3a45f085c896dbd8ed405f2023-11-22T09:22:44ZengMDPI AGPolymers2073-43602021-08-011316267910.3390/polym13162679Poly(butylene succinate-<i>co</i>-ε-caprolactone) Copolyesters: Enzymatic Synthesis in Bulk and Thermal PropertiesMaría Núñez0Sebastián Muñoz-Guerra1Antxon Martínez de Ilarduya2Departament d’Enginyeria Química, Universitat Politècnica de Catalunya, ETSEIB, Diagonal 647, 08028 Barcelona, SpainDepartament d’Enginyeria Química, Universitat Politècnica de Catalunya, ETSEIB, Diagonal 647, 08028 Barcelona, SpainDepartament d’Enginyeria Química, Universitat Politècnica de Catalunya, ETSEIB, Diagonal 647, 08028 Barcelona, SpainThis work explores for the first time the enzymatic synthesis of poly(butylene-<i>co</i>-ε-caprolactone) (PBSCL) copolyesters in bulk using commercially available monomers (dimethyl succinate (DMS), 1,4-butanediol (BD), and ε-caprolactone (CL)). A preliminary kinetic study was carried out which demonstrated the higher reactivity of DMS over CL in the condensation/ring opening polymerization reaction, catalyzed by <i>Candida antarctica</i> lipase B. PBSCL copolyesters were obtained with high molecular weights and a random microstructure, as determined by <sup>13</sup>C NMR. They were thermally stable up to 300 °C, with thermal stability increasing with the content of CL in the copolyester. All of them were semicrystalline, with melting temperatures and enthalpies decreasing up to the eutectic point observed at intermediate compositions, and glass transition temperatures decreasing with the content of CL in the copolyester. The use of CALB provided copolyesters free from toxic metallic catalyst, which is very useful if the polymer is intended to be used for biomedical applications.https://www.mdpi.com/2073-4360/13/16/2679aliphatic polyesterspoly(butylene succinate-<i>co</i>-ε-caprolactone)enzymatic synthesisCALB lipasemolecular weightsmicrostructure |
| spellingShingle | María Núñez Sebastián Muñoz-Guerra Antxon Martínez de Ilarduya Poly(butylene succinate-<i>co</i>-ε-caprolactone) Copolyesters: Enzymatic Synthesis in Bulk and Thermal Properties Polymers aliphatic polyesters poly(butylene succinate-<i>co</i>-ε-caprolactone) enzymatic synthesis CALB lipase molecular weights microstructure |
| title | Poly(butylene succinate-<i>co</i>-ε-caprolactone) Copolyesters: Enzymatic Synthesis in Bulk and Thermal Properties |
| title_full | Poly(butylene succinate-<i>co</i>-ε-caprolactone) Copolyesters: Enzymatic Synthesis in Bulk and Thermal Properties |
| title_fullStr | Poly(butylene succinate-<i>co</i>-ε-caprolactone) Copolyesters: Enzymatic Synthesis in Bulk and Thermal Properties |
| title_full_unstemmed | Poly(butylene succinate-<i>co</i>-ε-caprolactone) Copolyesters: Enzymatic Synthesis in Bulk and Thermal Properties |
| title_short | Poly(butylene succinate-<i>co</i>-ε-caprolactone) Copolyesters: Enzymatic Synthesis in Bulk and Thermal Properties |
| title_sort | poly butylene succinate i co i ε caprolactone copolyesters enzymatic synthesis in bulk and thermal properties |
| topic | aliphatic polyesters poly(butylene succinate-<i>co</i>-ε-caprolactone) enzymatic synthesis CALB lipase molecular weights microstructure |
| url | https://www.mdpi.com/2073-4360/13/16/2679 |
| work_keys_str_mv | AT marianunez polybutylenesuccinateicoiecaprolactonecopolyestersenzymaticsynthesisinbulkandthermalproperties AT sebastianmunozguerra polybutylenesuccinateicoiecaprolactonecopolyestersenzymaticsynthesisinbulkandthermalproperties AT antxonmartinezdeilarduya polybutylenesuccinateicoiecaprolactonecopolyestersenzymaticsynthesisinbulkandthermalproperties |