(Bio)Sensing Strategies Based on Ionic Liquid-Functionalized Carbon Nanocomposites for Pharmaceuticals: Towards Greener Electrochemical Tools
The interaction of carbon-based nanomaterials and ionic liquids (ILs) has been thoroughly exploited for diverse electroanalytical solutions since the first report in 2003. This combination, either through covalent or non-covalent functionalization, takes advantage of the unique characteristics inher...
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| Format: | Article |
| Language: | English |
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MDPI AG
2022-07-01
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| Series: | Nanomaterials |
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| Online Access: | https://www.mdpi.com/2079-4991/12/14/2368 |
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| author | Álvaro Torrinha Thiago M. B. F. Oliveira Francisco W. P. Ribeiro Pedro de Lima-Neto Adriana N. Correia Simone Morais |
| author_facet | Álvaro Torrinha Thiago M. B. F. Oliveira Francisco W. P. Ribeiro Pedro de Lima-Neto Adriana N. Correia Simone Morais |
| author_sort | Álvaro Torrinha |
| collection | DOAJ |
| description | The interaction of carbon-based nanomaterials and ionic liquids (ILs) has been thoroughly exploited for diverse electroanalytical solutions since the first report in 2003. This combination, either through covalent or non-covalent functionalization, takes advantage of the unique characteristics inherent to each material, resulting in synergistic effects that are conferred to the electrochemical (bio)sensing system. From one side, carbon nanomaterials offer miniaturization capacity with enhanced electron transfer rates at a reduced cost, whereas from the other side, ILs contribute as ecological dispersing media for the nanostructures, improving conductivity and biocompatibility. The present review focuses on the use of this interesting type of nanocomposites for the development of (bio)sensors specifically for pharmaceutical detection, with emphasis on the analytical (bio)sensing features. The literature search displayed the conjugation of more than 20 different ILs and several carbon nanomaterials (MWCNT, SWCNT, graphene, carbon nanofibers, fullerene, and carbon quantum dots, among others) that were applied for a large set (about 60) of pharmaceutical compounds. This great variability causes a straightforward comparison between sensors to be a challenging task. Undoubtedly, electrochemical sensors based on the conjugation of carbon nanomaterials with ILs can potentially be established as sustainable analytical tools and viable alternatives to more traditional methods, especially concerning in situ environmental analysis. |
| first_indexed | 2024-03-09T13:16:40Z |
| format | Article |
| id | doaj.art-9ea1b26517d743459d95b02fa4210692 |
| institution | Directory Open Access Journal |
| issn | 2079-4991 |
| language | English |
| last_indexed | 2024-03-09T13:16:40Z |
| publishDate | 2022-07-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Nanomaterials |
| spelling | doaj.art-9ea1b26517d743459d95b02fa42106922023-11-30T21:35:18ZengMDPI AGNanomaterials2079-49912022-07-011214236810.3390/nano12142368(Bio)Sensing Strategies Based on Ionic Liquid-Functionalized Carbon Nanocomposites for Pharmaceuticals: Towards Greener Electrochemical ToolsÁlvaro Torrinha0Thiago M. B. F. Oliveira1Francisco W. P. Ribeiro2Pedro de Lima-Neto3Adriana N. Correia4Simone Morais5REQUIMTE-LAQV, Instituto Superior de Engenharia do Porto, Instituto Politécnico do Porto, Rua Dr. António Bernardino de Almeida, 431, 4249-015 Porto, PortugalCentro de Ciência e Tecnologia, Universidade Federal do Cariri, Av. Tenente Raimundo Rocha, 1639, Cidade Universitária, Juazeiro do Norte 63048-080, BrazilInstituto de Formação de Educadores, Universidade Federal do Cariri, Rua Olegário Emídio de Araújo, S/N, Centro, Brejo Santo 63260-000, BrazilCentro de Ciências, Departamento de Química Analítica e Físico-Química, Universidade Federal do Ceará, Bloco 940, Campus do Pici, Fortaleza 60440-900, BrazilCentro de Ciências, Departamento de Química Analítica e Físico-Química, Universidade Federal do Ceará, Bloco 940, Campus do Pici, Fortaleza 60440-900, BrazilREQUIMTE-LAQV, Instituto Superior de Engenharia do Porto, Instituto Politécnico do Porto, Rua Dr. António Bernardino de Almeida, 431, 4249-015 Porto, PortugalThe interaction of carbon-based nanomaterials and ionic liquids (ILs) has been thoroughly exploited for diverse electroanalytical solutions since the first report in 2003. This combination, either through covalent or non-covalent functionalization, takes advantage of the unique characteristics inherent to each material, resulting in synergistic effects that are conferred to the electrochemical (bio)sensing system. From one side, carbon nanomaterials offer miniaturization capacity with enhanced electron transfer rates at a reduced cost, whereas from the other side, ILs contribute as ecological dispersing media for the nanostructures, improving conductivity and biocompatibility. The present review focuses on the use of this interesting type of nanocomposites for the development of (bio)sensors specifically for pharmaceutical detection, with emphasis on the analytical (bio)sensing features. The literature search displayed the conjugation of more than 20 different ILs and several carbon nanomaterials (MWCNT, SWCNT, graphene, carbon nanofibers, fullerene, and carbon quantum dots, among others) that were applied for a large set (about 60) of pharmaceutical compounds. This great variability causes a straightforward comparison between sensors to be a challenging task. Undoubtedly, electrochemical sensors based on the conjugation of carbon nanomaterials with ILs can potentially be established as sustainable analytical tools and viable alternatives to more traditional methods, especially concerning in situ environmental analysis.https://www.mdpi.com/2079-4991/12/14/2368ionic liquidcarbon nanomaterialselectrochemical sensorspharmaceuticalselectroanalysis |
| spellingShingle | Álvaro Torrinha Thiago M. B. F. Oliveira Francisco W. P. Ribeiro Pedro de Lima-Neto Adriana N. Correia Simone Morais (Bio)Sensing Strategies Based on Ionic Liquid-Functionalized Carbon Nanocomposites for Pharmaceuticals: Towards Greener Electrochemical Tools Nanomaterials ionic liquid carbon nanomaterials electrochemical sensors pharmaceuticals electroanalysis |
| title | (Bio)Sensing Strategies Based on Ionic Liquid-Functionalized Carbon Nanocomposites for Pharmaceuticals: Towards Greener Electrochemical Tools |
| title_full | (Bio)Sensing Strategies Based on Ionic Liquid-Functionalized Carbon Nanocomposites for Pharmaceuticals: Towards Greener Electrochemical Tools |
| title_fullStr | (Bio)Sensing Strategies Based on Ionic Liquid-Functionalized Carbon Nanocomposites for Pharmaceuticals: Towards Greener Electrochemical Tools |
| title_full_unstemmed | (Bio)Sensing Strategies Based on Ionic Liquid-Functionalized Carbon Nanocomposites for Pharmaceuticals: Towards Greener Electrochemical Tools |
| title_short | (Bio)Sensing Strategies Based on Ionic Liquid-Functionalized Carbon Nanocomposites for Pharmaceuticals: Towards Greener Electrochemical Tools |
| title_sort | bio sensing strategies based on ionic liquid functionalized carbon nanocomposites for pharmaceuticals towards greener electrochemical tools |
| topic | ionic liquid carbon nanomaterials electrochemical sensors pharmaceuticals electroanalysis |
| url | https://www.mdpi.com/2079-4991/12/14/2368 |
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