B21 DNA vaccine expressing ag85b, rv2029c, and rv1738 confers a robust therapeutic effect against latent Mycobacterium tuberculosis infection

B21 DNA vaccine expressing ag85b, rv2029c, and rv1738 confers a robust therapeutic effect against latent Mycobacterium tuberculosis infection

Latent tuberculosis infection (LTBI) treatment is known to accelerate the decline in TB incidence, especially in high-risk populations. Mycobacterium tuberculosis (M. tb) expression profiles differ at different growth periods, and vaccines protective and therapeutic effects may increase when they in...

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Bibliographic Details
Main Authors: Shufeng Weng, Jinyi Zhang, Huixia Ma, Jingyu Zhou, Liqiu Jia, Yanmin Wan, Peng Cui, Qiaoling Ruan, Lingyun Shao, Jing Wu, Honghai Wang, Wenhong Zhang, Ying Xu
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-12-01
Series:Frontiers in Immunology
Subjects:
DNA vaccine
immunotherapy
Mycobacterium tuberculosis
LTBI
B21 DNA
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.1025931/full

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