PERFORMANCE OF THE JOUYBAN-ACREE MODEL FOR CORRELATING THE SOLUBILITY OF INDOMETHACIN AND ETHYLHEXYL TRIAZONE IN ETHYL ACETATE + ETHANOL MIXTURES

This work reports the experimental volumetric properties and also the saturated solubility of indomethacin and ethylhexyl triazine in ethyl acetate + ethanol mixtures at 293.15 to 313.15 K and evaluates the validity of the Jouyban-Acree (J & A) model to correlate the solubility of these compound...

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Bibliographic Details
Main Authors: Miller A. RUIDIAZ M., Sylvia J. RODRÍGUEZ D., Paula C. NEITA R., Diana M. CRISTANCHO B., Fleming MARTÍNEZ R.
Format: Article
Language:English
Published: Universidad de Antioquia 2010-11-01
Series:Vitae
Subjects:
Online Access:https://revistas.udea.edu.co/index.php/vitae/article/view/7438
Description
Summary:This work reports the experimental volumetric properties and also the saturated solubility of indomethacin and ethylhexyl triazine in ethyl acetate + ethanol mixtures at 293.15 to 313.15 K and evaluates the validity of the Jouyban-Acree (J & A) model to correlate the solubility of these compounds in ethyl acetate + ethanol solvent mixtures. The solubility correlation is studied as a function of temperature and cosolvent composition. The J & A model requires only the experimental solubility values in the pure solvents at all the temperatures under study. The calculated values by using both compounds deviate as mean in 30% from experimental solubility values.
ISSN:0121-4004
2145-2660