Renal transplantation using kidneys from hepatitis C-infected donors: A review of 30-years’ experience
Kidney transplantation is the optimal therapy for end-stage kidney disease but limited by the available number of organs. Using HCV+ donors, both in HCV+ and HCV− recipients, is a rational response to the organ shortage. We review the historic experience using HCV+ donors in HCV+ recipients and asse...
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| Format: | Article |
| Language: | English |
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Elsevier
2023-03-01
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| Series: | Nefrología (English Edition) |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S201325142200178X |
| _version_ | 1797776670899306496 |
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| author | Deirdre Sawinski Russel E. Rosenblatt Jose Maria Morales |
| author_facet | Deirdre Sawinski Russel E. Rosenblatt Jose Maria Morales |
| author_sort | Deirdre Sawinski |
| collection | DOAJ |
| description | Kidney transplantation is the optimal therapy for end-stage kidney disease but limited by the available number of organs. Using HCV+ donors, both in HCV+ and HCV− recipients, is a rational response to the organ shortage. We review the historic experience using HCV+ donors in HCV+ recipients and assess long-term results. We also discuss contemporary practices, including the transplantation of HCV-viremic kidneys into HCV− recipients with different approaches to posttransplant HCV therapy. Resumen: El trasplante renal es el tratamiento óptimo de la insuficiencia renal terminal pero está limitado por el número de órganos disponibles. El uso de los riñones de los donantes VHC+, tanto en receptores VHC+ como VHC−, es una respuesta racional a la escasez de órganos. En este artículo revisamos la experiencia histórica usando riñones de donantes VHC+ en receptores VHC+ y evaluamos los resultados a largo plazo. Además, discutiremos las prácticas contemporáneas incluyendo el trasplante de órganos VHC+ virémicos en receptores VHC− con diferentes opciones de tratamiento VHC postrasplante. |
| first_indexed | 2024-03-12T22:53:14Z |
| format | Article |
| id | doaj.art-9eaa8c8c5db241be970704af4d148922 |
| institution | Directory Open Access Journal |
| issn | 2013-2514 |
| language | English |
| last_indexed | 2024-03-12T22:53:14Z |
| publishDate | 2023-03-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Nefrología (English Edition) |
| spelling | doaj.art-9eaa8c8c5db241be970704af4d1489222023-07-20T04:38:15ZengElsevierNefrología (English Edition)2013-25142023-03-01432182188Renal transplantation using kidneys from hepatitis C-infected donors: A review of 30-years’ experienceDeirdre Sawinski0Russel E. Rosenblatt1Jose Maria Morales2Division of Nephrology and Hypertension, Department of Medicine, Weill Cornell Medicine, New York, NY, USADivision of Gastroenterology and Hepatology, Department of Medicine, Weill Cornell Medicine, New York, NY, USAResearch Institute, Hospital 12 de Octubre, Madrid, Spain; Corresponding author.Kidney transplantation is the optimal therapy for end-stage kidney disease but limited by the available number of organs. Using HCV+ donors, both in HCV+ and HCV− recipients, is a rational response to the organ shortage. We review the historic experience using HCV+ donors in HCV+ recipients and assess long-term results. We also discuss contemporary practices, including the transplantation of HCV-viremic kidneys into HCV− recipients with different approaches to posttransplant HCV therapy. Resumen: El trasplante renal es el tratamiento óptimo de la insuficiencia renal terminal pero está limitado por el número de órganos disponibles. El uso de los riñones de los donantes VHC+, tanto en receptores VHC+ como VHC−, es una respuesta racional a la escasez de órganos. En este artículo revisamos la experiencia histórica usando riñones de donantes VHC+ en receptores VHC+ y evaluamos los resultados a largo plazo. Además, discutiremos las prácticas contemporáneas incluyendo el trasplante de órganos VHC+ virémicos en receptores VHC− con diferentes opciones de tratamiento VHC postrasplante.http://www.sciencedirect.com/science/article/pii/S201325142200178XVHCTrasplante renalDAA |
| spellingShingle | Deirdre Sawinski Russel E. Rosenblatt Jose Maria Morales Renal transplantation using kidneys from hepatitis C-infected donors: A review of 30-years’ experience Nefrología (English Edition) VHC Trasplante renal DAA |
| title | Renal transplantation using kidneys from hepatitis C-infected donors: A review of 30-years’ experience |
| title_full | Renal transplantation using kidneys from hepatitis C-infected donors: A review of 30-years’ experience |
| title_fullStr | Renal transplantation using kidneys from hepatitis C-infected donors: A review of 30-years’ experience |
| title_full_unstemmed | Renal transplantation using kidneys from hepatitis C-infected donors: A review of 30-years’ experience |
| title_short | Renal transplantation using kidneys from hepatitis C-infected donors: A review of 30-years’ experience |
| title_sort | renal transplantation using kidneys from hepatitis c infected donors a review of 30 years experience |
| topic | VHC Trasplante renal DAA |
| url | http://www.sciencedirect.com/science/article/pii/S201325142200178X |
| work_keys_str_mv | AT deirdresawinski renaltransplantationusingkidneysfromhepatitiscinfecteddonorsareviewof30yearsexperience AT russelerosenblatt renaltransplantationusingkidneysfromhepatitiscinfecteddonorsareviewof30yearsexperience AT josemariamorales renaltransplantationusingkidneysfromhepatitiscinfecteddonorsareviewof30yearsexperience |