Perioperative adjuvant corticosteroids for post-operative analgesia in elective knee surgery – A systematic review
Abstract Background Elective knee surgery is performed to reduce chronic pain and improve function in degenerate knees. Treatment of acute post-operative pain is suboptimal in 75% of patients despite multimodal analgesic approaches resulting in higher post-operative opiate consumption. The effect of...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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BMC
2017-04-01
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| Series: | Systematic Reviews |
| Subjects: | |
| Online Access: | http://link.springer.com/article/10.1186/s13643-017-0485-8 |
| _version_ | 1818827729011736576 |
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| author | Hasan Raza Mohammad Marialena Trivella Thomas W. Hamilton Louise Strickland David Murray Hemant Pandit |
| author_facet | Hasan Raza Mohammad Marialena Trivella Thomas W. Hamilton Louise Strickland David Murray Hemant Pandit |
| author_sort | Hasan Raza Mohammad |
| collection | DOAJ |
| description | Abstract Background Elective knee surgery is performed to reduce chronic pain and improve function in degenerate knees. Treatment of acute post-operative pain is suboptimal in 75% of patients despite multimodal analgesic approaches resulting in higher post-operative opiate consumption. The effect of corticosteroids as an adjunct for post-operative pain control remains undefined. Methods The databases MEDLINE, EMBASE and CENTRAL (Cochrane library) will be searched from their inception to present using broad search criteria for eligible randomised/quasi-randomised controlled trials investigating perioperative corticosteroid adjunctive use in elective knee surgery. Meta-analyses will be conducted according to the recommendations from the Cochrane Handbook for Systematic Reviews of Interventions. Discussion This systematic review of the perioperative adjunctive use of corticosteroids will assess the analgesic effects, post-operative nausea and vomiting, opiate consumption, infection rates and time till discharge and assess whether adjunctive corticosteroids should be encouraged in elective knee surgery. Systematic review registration PROPSERO CRD42016049336 |
| first_indexed | 2024-12-19T00:48:11Z |
| format | Article |
| id | doaj.art-9eabbac9fb4344c3b396c629c8aa7d36 |
| institution | Directory Open Access Journal |
| issn | 2046-4053 |
| language | English |
| last_indexed | 2024-12-19T00:48:11Z |
| publishDate | 2017-04-01 |
| publisher | BMC |
| record_format | Article |
| series | Systematic Reviews |
| spelling | doaj.art-9eabbac9fb4344c3b396c629c8aa7d362022-12-21T20:44:12ZengBMCSystematic Reviews2046-40532017-04-01611810.1186/s13643-017-0485-8Perioperative adjuvant corticosteroids for post-operative analgesia in elective knee surgery – A systematic reviewHasan Raza Mohammad0Marialena Trivella1Thomas W. Hamilton2Louise Strickland3David Murray4Hemant Pandit5Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences (NDORMS), University of OxfordCentre for Statistics in Medicine, University of OxfordNuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences (NDORMS), University of OxfordNuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences (NDORMS), University of OxfordNuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences (NDORMS), University of OxfordNuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences (NDORMS), University of OxfordAbstract Background Elective knee surgery is performed to reduce chronic pain and improve function in degenerate knees. Treatment of acute post-operative pain is suboptimal in 75% of patients despite multimodal analgesic approaches resulting in higher post-operative opiate consumption. The effect of corticosteroids as an adjunct for post-operative pain control remains undefined. Methods The databases MEDLINE, EMBASE and CENTRAL (Cochrane library) will be searched from their inception to present using broad search criteria for eligible randomised/quasi-randomised controlled trials investigating perioperative corticosteroid adjunctive use in elective knee surgery. Meta-analyses will be conducted according to the recommendations from the Cochrane Handbook for Systematic Reviews of Interventions. Discussion This systematic review of the perioperative adjunctive use of corticosteroids will assess the analgesic effects, post-operative nausea and vomiting, opiate consumption, infection rates and time till discharge and assess whether adjunctive corticosteroids should be encouraged in elective knee surgery. Systematic review registration PROPSERO CRD42016049336http://link.springer.com/article/10.1186/s13643-017-0485-8AnalgesiaCorticosteroidsKneePerioperativeSurgery |
| spellingShingle | Hasan Raza Mohammad Marialena Trivella Thomas W. Hamilton Louise Strickland David Murray Hemant Pandit Perioperative adjuvant corticosteroids for post-operative analgesia in elective knee surgery – A systematic review Systematic Reviews Analgesia Corticosteroids Knee Perioperative Surgery |
| title | Perioperative adjuvant corticosteroids for post-operative analgesia in elective knee surgery – A systematic review |
| title_full | Perioperative adjuvant corticosteroids for post-operative analgesia in elective knee surgery – A systematic review |
| title_fullStr | Perioperative adjuvant corticosteroids for post-operative analgesia in elective knee surgery – A systematic review |
| title_full_unstemmed | Perioperative adjuvant corticosteroids for post-operative analgesia in elective knee surgery – A systematic review |
| title_short | Perioperative adjuvant corticosteroids for post-operative analgesia in elective knee surgery – A systematic review |
| title_sort | perioperative adjuvant corticosteroids for post operative analgesia in elective knee surgery a systematic review |
| topic | Analgesia Corticosteroids Knee Perioperative Surgery |
| url | http://link.springer.com/article/10.1186/s13643-017-0485-8 |
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