Activation of Neuroprotective Microglia and Astrocytes at the Lesion Site and in the Adjacent Segments Is Crucial for Spontaneous Locomotor Recovery after Spinal Cord Injury

Activation of Neuroprotective Microglia and Astrocytes at the Lesion Site and in the Adjacent Segments Is Crucial for Spontaneous Locomotor Recovery after Spinal Cord Injury

Microglia and astrocytes play an important role in the regulation of immune responses under various pathological conditions. To detect environmental cues associated with the transformation of reactive microglia (M1) and astrocytes (A1) into their polarization states (anti-inflammatory M2 and A2 phen...

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Bibliographic Details
Main Authors: Alexandra Kisucká, Katarína Bimbová, Mária Bačová, Ján Gálik, Nadežda Lukáčová
Format: Article
Language:English
Published: MDPI AG 2021-07-01
Series:Cells
Subjects:
microglia/macrophages
microglial phenotypes: M1
M2a and M2c
A1 and A2 reactive astrocytes
Th9 compression
gene expression
Online Access:https://www.mdpi.com/2073-4409/10/8/1943

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