Dietary sodium butyrate improves female broiler breeder performance and offspring immune function by enhancing maternal intestinal barrier and microbiota
ABSTRACT: This study aimed to investigate the effects of dietary sodium butyrate (SB) supplementation on the reproductive performance of female broiler breeders under intensive rearing conditions and to analyze antioxidant capacity, immune function, and intestinal barrier function of the female bree...
| Main Authors: | , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2023-06-01
|
| Series: | Poultry Science |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S0032579123001815 |
| _version_ | 1827940993155989504 |
|---|---|
| author | Chuanpi Xiao Li Zhang Bo Zhang Linglian Kong Xue Pan Tim Goossens Zhigang Song |
| author_facet | Chuanpi Xiao Li Zhang Bo Zhang Linglian Kong Xue Pan Tim Goossens Zhigang Song |
| author_sort | Chuanpi Xiao |
| collection | DOAJ |
| description | ABSTRACT: This study aimed to investigate the effects of dietary sodium butyrate (SB) supplementation on the reproductive performance of female broiler breeders under intensive rearing conditions and to analyze antioxidant capacity, immune function, and intestinal barrier function of the female breeders and their offspring. A total of 96,000 40-wk-old Ross308 female broiler breeders were divided into the control (CON) and SB groups, each with 6 replicates of 8,000 birds. Each house with similar production performance characteristics was considered a replicate. The experiment lasted for 20 wk, whereupon sampling took place. Results showed that SB improved the egg production performance, egg quality of broiler breeders, and hatchability (P < 0.05). Maternal supplementation with SB substantially increased serum immunoglobulin A levels in broiler breeders and offspring (both P = 0.04) and offspring immunoglobulin G (P < 0.001). The levels of interleukin-1β (P < 0.001) and interleukin-4 (P = 0.03) in the offspring were downregulated, while the total superoxide dismutase in the offspring and the eggs increased (P < 0.05). The serum biochemical components in breeders and offspring were altered by SB, as evidenced by the reduction in triglycerides, total cholesterol, and high- and low-density lipoproteins (P < 0.05). The intestinal morphology of broiler breeders and offspring also improved by the SB with the decreasing the jejunal crypt depth (P = 0.04) and increasing villus height in offspring (P = 0.03). Maternal jejunal and ileal intestinal barrier-related genes were also shown to be significantly affected by SB. Furthermore, SB altered the microbial diversity in maternal cecal contents, thus increasing the abundance of Lachnospiraceae (P = 0.004) and Ruminococcaceae (P = 0.03). Dietary SB enhanced the reproductive performance and egg quality of broiler breeders and improved the antioxidant capacity and immune function of broiler breeders and offspring, with the benefits potentially arising from the regulation of the maternal intestinal barrier and gut microbiota by SB. |
| first_indexed | 2024-03-13T09:29:22Z |
| format | Article |
| id | doaj.art-9eb056077afd480a92afae1cf5838119 |
| institution | Directory Open Access Journal |
| issn | 0032-5791 |
| language | English |
| last_indexed | 2024-03-13T09:29:22Z |
| publishDate | 2023-06-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Poultry Science |
| spelling | doaj.art-9eb056077afd480a92afae1cf58381192023-05-26T04:20:46ZengElsevierPoultry Science0032-57912023-06-011026102658Dietary sodium butyrate improves female broiler breeder performance and offspring immune function by enhancing maternal intestinal barrier and microbiotaChuanpi Xiao0Li Zhang1Bo Zhang2Linglian Kong3Xue Pan4Tim Goossens5Zhigang Song6Key Laboratory of Efficient Utilization of Non-grain Feed Resources, Department of Animal Science, Shandong Agricultural University, Taian, Shandong, China; Precision Livestock and Nutrition Unit, Gembloux Agro-Bio Tech, University of Liège, Gembloux, BelgiumKey Laboratory of Efficient Utilization of Non-grain Feed Resources, Department of Animal Science, Shandong Agricultural University, Taian, Shandong, ChinaAdisseo Life Science Products (Shanghai) Co. Ltd., Shanghai, ChinaKey Laboratory of Efficient Utilization of Non-grain Feed Resources, Department of Animal Science, Shandong Agricultural University, Taian, Shandong, ChinaKey Laboratory of Efficient Utilization of Non-grain Feed Resources, Department of Animal Science, Shandong Agricultural University, Taian, Shandong, ChinaAdisseo France, Hoogveld, Dendermonde, BelgiumKey Laboratory of Efficient Utilization of Non-grain Feed Resources, Department of Animal Science, Shandong Agricultural University, Taian, Shandong, China; Corresponding author:ABSTRACT: This study aimed to investigate the effects of dietary sodium butyrate (SB) supplementation on the reproductive performance of female broiler breeders under intensive rearing conditions and to analyze antioxidant capacity, immune function, and intestinal barrier function of the female breeders and their offspring. A total of 96,000 40-wk-old Ross308 female broiler breeders were divided into the control (CON) and SB groups, each with 6 replicates of 8,000 birds. Each house with similar production performance characteristics was considered a replicate. The experiment lasted for 20 wk, whereupon sampling took place. Results showed that SB improved the egg production performance, egg quality of broiler breeders, and hatchability (P < 0.05). Maternal supplementation with SB substantially increased serum immunoglobulin A levels in broiler breeders and offspring (both P = 0.04) and offspring immunoglobulin G (P < 0.001). The levels of interleukin-1β (P < 0.001) and interleukin-4 (P = 0.03) in the offspring were downregulated, while the total superoxide dismutase in the offspring and the eggs increased (P < 0.05). The serum biochemical components in breeders and offspring were altered by SB, as evidenced by the reduction in triglycerides, total cholesterol, and high- and low-density lipoproteins (P < 0.05). The intestinal morphology of broiler breeders and offspring also improved by the SB with the decreasing the jejunal crypt depth (P = 0.04) and increasing villus height in offspring (P = 0.03). Maternal jejunal and ileal intestinal barrier-related genes were also shown to be significantly affected by SB. Furthermore, SB altered the microbial diversity in maternal cecal contents, thus increasing the abundance of Lachnospiraceae (P = 0.004) and Ruminococcaceae (P = 0.03). Dietary SB enhanced the reproductive performance and egg quality of broiler breeders and improved the antioxidant capacity and immune function of broiler breeders and offspring, with the benefits potentially arising from the regulation of the maternal intestinal barrier and gut microbiota by SB.http://www.sciencedirect.com/science/article/pii/S0032579123001815broiler breedergut microbiotaoffspringreproductive performancesodium butyrate |
| spellingShingle | Chuanpi Xiao Li Zhang Bo Zhang Linglian Kong Xue Pan Tim Goossens Zhigang Song Dietary sodium butyrate improves female broiler breeder performance and offspring immune function by enhancing maternal intestinal barrier and microbiota Poultry Science broiler breeder gut microbiota offspring reproductive performance sodium butyrate |
| title | Dietary sodium butyrate improves female broiler breeder performance and offspring immune function by enhancing maternal intestinal barrier and microbiota |
| title_full | Dietary sodium butyrate improves female broiler breeder performance and offspring immune function by enhancing maternal intestinal barrier and microbiota |
| title_fullStr | Dietary sodium butyrate improves female broiler breeder performance and offspring immune function by enhancing maternal intestinal barrier and microbiota |
| title_full_unstemmed | Dietary sodium butyrate improves female broiler breeder performance and offspring immune function by enhancing maternal intestinal barrier and microbiota |
| title_short | Dietary sodium butyrate improves female broiler breeder performance and offspring immune function by enhancing maternal intestinal barrier and microbiota |
| title_sort | dietary sodium butyrate improves female broiler breeder performance and offspring immune function by enhancing maternal intestinal barrier and microbiota |
| topic | broiler breeder gut microbiota offspring reproductive performance sodium butyrate |
| url | http://www.sciencedirect.com/science/article/pii/S0032579123001815 |
| work_keys_str_mv | AT chuanpixiao dietarysodiumbutyrateimprovesfemalebroilerbreederperformanceandoffspringimmunefunctionbyenhancingmaternalintestinalbarrierandmicrobiota AT lizhang dietarysodiumbutyrateimprovesfemalebroilerbreederperformanceandoffspringimmunefunctionbyenhancingmaternalintestinalbarrierandmicrobiota AT bozhang dietarysodiumbutyrateimprovesfemalebroilerbreederperformanceandoffspringimmunefunctionbyenhancingmaternalintestinalbarrierandmicrobiota AT lingliankong dietarysodiumbutyrateimprovesfemalebroilerbreederperformanceandoffspringimmunefunctionbyenhancingmaternalintestinalbarrierandmicrobiota AT xuepan dietarysodiumbutyrateimprovesfemalebroilerbreederperformanceandoffspringimmunefunctionbyenhancingmaternalintestinalbarrierandmicrobiota AT timgoossens dietarysodiumbutyrateimprovesfemalebroilerbreederperformanceandoffspringimmunefunctionbyenhancingmaternalintestinalbarrierandmicrobiota AT zhigangsong dietarysodiumbutyrateimprovesfemalebroilerbreederperformanceandoffspringimmunefunctionbyenhancingmaternalintestinalbarrierandmicrobiota |